sstr1
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  • Official Full Name
  • somatostatin receptor 1
  • Background
  • Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.
  • Synonyms
  • SSTR1; somatostatin receptor 1; somatostatin receptor type 1; G-protein coupled receptor; SS1R; SS1-R; SRIF-2; SS-1-R
Cat.#:SSTR1-2970HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SSTR1, GST-tagged
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Cat.#:SSTR1-16042MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SSTR1 Protein
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Cat.#:SSTR1-5760RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SSTR1 Protein
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Cat.#:SSTR1-3796CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SSTR1
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Cat.#:SSTR1-1453HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SSTR1 293 Cell Lysate
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Cat.#:Kit-1520Tag:N/A
Source (Host):Species:
Product nameSSTR1 U2OS β-Arrestin GPCR Assay Kit
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Cat.#:Kit-0942Tag:N/A
Source (Host):Species:
Product namePPARĪ³-Competitor Assay Kit, Green
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Involved Pathway

SSTR1 involved in several pathways and played different roles in them. We selected most pathways SSTR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSTR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)
HEBP1; S1PR1; EDNRAB; PROK2; PMCH; PNOCB; GPR132B; DRD1; CCK; UTS2
G alpha (i) signalling events
PENKB; OPN1LW; CXCL13; OPN1SW1; OPN1MW2; AMCF-II; RGS14; ADRA2A; RGS4; AGT
GPCR downstream signaling
SOUL4; RGS18; OPN4B; DGKB; PENKA; HCAR1-2; EDNRA; RGS12; OPN4A; GPR55
GPCR ligand binding
RXFP2; SETD6; RGR; GCGB; AGTR2; HCRT; GPBAR1; GPR31B; CALCB; KISS1
GPCRs, Class A Rhodopsin-like
SSTR3; GPR1; CCR3; OPN1MW2; OPN1LW; CNR1; CCR9; LTB4R; CNR2; OPN1SW
Neuroactive ligand-receptor interaction
TAAR12A; PTH1RB; GRIK3; CHRNA9; GALR3; PTGER2; TACR1B; GRM8B; MAS1; GABBR1
Peptide GPCRs
TAC4; CXCR6; SSTR1; SSTR4; SSTR5; CX3CR1
Peptide ligand-binding receptors
PENK; TRH; INSL5; SSTR5; CXCR7B; INSL3; GAL; SSTR4; GPR37B; TAC1

Protein Function

SSTR1 has several biochemical functions, for example, neuropeptide binding, somatostatin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SSTR1 itself. We selected most functions SSTR1 had, and list some proteins which have the same functions with SSTR1. You can find most of the proteins on our site.
Function
Related Protein
Function neuropeptide binding
Related Protein PTGDR2; GPR1; NPBWR1; OPRL1; MC4R; MC3R; OPRM1; OPRK1; MRGPRX2; SSTR2
Function somatostatin receptor activity
Related Protein SSTR2; SSTR1; SSTR3; SSTR5; SSTR4

SSTR1 Related Articles

Elston, MS; Meyer-Rochow, GY; et al. Increased SSTR2A and SSTR3 expression in succinate dehydrogenase-deficient pheochromocytomas and paragangliomas. HUMAN PATHOLOGY 46:390-396(2015).
Lambertini, C; Barzaghi-Rinaudo, P; et al. Evaluation of somatostatin receptor subtype expression in human neuroendocrine tumors using two sets of new monoclonal antibodies. REGULATORY PEPTIDES 187:35-41(2013).