This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009]
SUCNR1 involved in several pathways and played different roles in them. We selected most pathways SUCNR1 participated on our site, such as cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUCNR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
SUCNR1 has several biochemical functions, for example, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SUCNR1 itself. We selected most functions SUCNR1 had, and list some proteins which have the same functions with SUCNR1. You can find most of the proteins on our site.
Function G-protein coupled receptor activity
Related Protein MRGPRB5; OLFR149; F2RL1.1; OLFR491; SUCNR1; FPR-RS4; VMN1R43; GPR151; GPR176; GPR157
SUCNR1 Related Articles
Piacham, T; Nantasenamat, C; et al. SYNTHESIS AND COMPUTATIONAL INVESTIGATION OF MOLECULARLY IMPRINTED NANOSPHERES FOR SELECTIVE RECOGNITION OF ALPHA-TOCOPHEROL SUCCINATE. EXCLI JOURNAL 12:701-718(2013).
Chen, LW; Horng, LY; et al. Activating mitochondrial regulator PGC-1 alpha expression by astrocytic NGF is a therapeutic strategy for Huntington's disease. NEUROPHARMACOLOGY 63:719-732(2012).