taf1a
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  • Official Full Name
  • TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
  • Background
  • This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.
  • Synonyms
  • TAF1A; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa; TATA box binding protein (TBP) associated factor, RNA polymerase I, A, 48kD; TATA box-binding protein-associated factor RNA polymerase I subunit A; SL1; TAFI48; RAFI48; TATA box binding protein associated factor 1A; TATA box binding protein associated factor RNA polymerase I subunit A; TBP associated factor RNA polymerase I 48 kDa; Transcription factor SL1; SL1, 48kD subunit; OTTHUMP00000035653; OTTHUMP00000035654; OTTHUMP00000035655; TBP-associated factor 1A; TATA box-binding protein-associated factor 1A; transcription; MGC:17061
Cat.#:TAF1A-2448HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TAF1A
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Cat.#:TAF1A-3102HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TAF1A, His-tagged
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Cat.#:TAF1A-16390MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TAF1A Protein
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Cat.#:TAF1A-5913RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TAF1A Protein
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Cat.#:TAF1A-4947CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TAF1A
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Cat.#:TAF1A-4272ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TAF1A
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Cat.#:TAF1A-1272HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TAF1A 293 Cell Lysate
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Cat.#:TAF1A-1273HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TAF1A 293 Cell Lysate
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Involved Pathway

TAF1A involved in several pathways and played different roles in them. We selected most pathways TAF1A participated on our site, such as Epigenetic regulation of gene expression, Gene Expression, Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Epigenetic regulation of gene expression
PHF19; AEBP2; TAF1D; TET2; DNMT3B; BAZ2A; TAF1A; SAP18; CD3EAP; SAP30
Gene Expression
ZFP90; ZNF394; NR2F6; PAIP1; HELZ2; ALKBH8; SKIB; ZNF597; AIMP2; AEBP2
Negative epigenetic regulation of rRNA expression
SAP30; BAZ2A; DNMT3B; TAF1C; TAF1D; TAF1B; RRP8; SAP18; TAF1A; SAP30BP
NoRC negatively regulates rRNA expression
SAP30BP; TAF1C; CD3EAP; TAF1A; DNMT3B; TAF1D; EFCAB11; BAZ2A; SIN3B; DNMT1
RNA Polymerase I Chain Elongation
TAF1D; TAF1C; TAF1A; TAF1B; CBX3A; CD3EAP; EFCAB11; UBTF; CBX3
RNA Polymerase I Promoter Clearance
EHMT2; TAF1C; MBD3B; RRN3; TAF1D; CHD4; MTA3; EFCAB11; GATAD2B; MBD3
RNA Polymerase I Promoter Escape
RRN3; UBTF; TAF1B; TAF1C; TAF1D; CD3EAP; EFCAB11; TAF1A
RNA Polymerase I Transcription
CHD4; GATAD2AB; TAF1B; UBTF; MTA1; PTRFB; CHD4A; MBD3A; MTA2; RRN3

Protein Function

TAF1A has several biochemical functions, for example, DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1A itself. We selected most functions TAF1A had, and list some proteins which have the same functions with TAF1A. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein HIST3H2A; HLX1; RBM6; FOXE3; HIST2H2BE; AKAP8L; EVX2; HOXB13A; BCLAF1; ZNF620
Function protein binding
Related Protein CRLF1; EMD; MAB21L2; FASN; ITPR1; CYBB; TAOK1; TSEN54; PRUNE; FOXP1

Interacting Protein

TAF1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1A here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1A.
TBP; C11orf57; C11orf57; SET; TAF1B; TAF1D; JMJD6; Wdr5; Kif22; Kif15; NAF1; VWA9