tesk1
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  • Official Full Name
  • testis-specific kinase 1
  • Background
  • Testis-specific kinase 1 (TESK1) is a LIMK-related protein kinase originally identified to be expressed highly in testes and subsequently shown to be expressed in a wide variety of tissues and cell types (1-4). TESK1 phosphorylates the actin severing prot
  • Synonyms
  • TESK1; testis-specific kinase 1; dual specificity testis-specific protein kinase 1; testis specific kinase 1; testicular protein kinase 1
Cat.#:TESK1-7024HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human TESK1, GST-tagged
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Cat.#:TESK1-8071HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TESK1 protein, His & T7-tagged
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Cat.#:TESK1-16649MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TESK1 Protein
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Cat.#:Tesk1-8072MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tesk1 protein, His & T7-tagged
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Cat.#:TESK1-6016RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TESK1 Protein
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Cat.#:TESK1-4668RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TESK1 Protein, His-tagged
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Involved Pathway

TESK1 involved in several pathways and played different roles in them. We selected most pathways TESK1 participated on our site, such as Cell junction organization, Cell-Cell communication, Cell-extracellular matrix interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with TESK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell junction organization
CLDN3; PVRL1A; CDH10; CDH12; INADL; LIMS1; CDH6; CDH17; RSU1; JUPA
Cell-Cell communication
PLECA; KIRREL3L; CDH6; CADM2A; CTNND1; CDH10; CDH18A; CDH12; FERMT2; KIRREL
Cell-extracellular matrix interactions
FBLIM1; RSU1; ITGB1B.1; TESK1; FERMT2; PARVB; LIMS1
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
TESK1; LIMS1; PARVB; RSU1

Protein Function

TESK1 has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TESK1 itself. We selected most functions TESK1 had, and list some proteins which have the same functions with TESK1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PI4KB; MAP2K5; GTF2F2B; ATP11A; ABCC9; ATP13A1; PAPD4; PTK2BB; KIAA1804; PRKCA
Function metal ion binding
Related Protein PRSS1; PPARG; SNAI1A; ZBTB7A; ACAP2; CHPF; SIRT4; PPP2R3C; ITGA9; ZSCAN2
Function protein binding
Related Protein PODXL2; TRPC1; GLUD1; ZNF567; ARL2BP; SRSF10; UBXN6; PIK3R4; ARRB1; MOB3C
Function protein serine/threonine kinase activity
Related Protein CLK3; LATS1; STK40; MAPK1; CDK1; MYO3B; SLK; CSNK1D; TRPM6; PAK4
Function protein serine/threonine/tyrosine kinase activity
Related Protein DYRK1A; CLK1; ACVR2B; DSTYK; MAP2K1; DYRK3; DYRK2; RPS6KA1; SGK1; DYRK1B
Function protein tyrosine kinase activity
Related Protein SHC1; FGFR1OP; SRMS; KITB; JAK2B; LYN; MAP3K9; JAK2; EPHB4B; NEK1

Interacting Protein

TESK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TESK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TESK1.
YWHAB; SPRY4; HSP90AB1; ARAF; PFKL; ABCB4; YY1