tll2
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  • Official Full Name
  • tolloid-like 2
  • Synonyms
  • TLL2;tolloid-like 2;11844;ENSG00000095587;10q23-q24;KIAA0932, MGC133312, MGC133313;tolloid-like protein 2;tolloid-like protein 2;
Cat.#:TLL2-3255HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TLL2, His-tagged
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Cat.#:TLL2-1048HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TLL2 293 Cell Lysate
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Involved Pathway

TLL2 involved in several pathways and played different roles in them. We selected most pathways TLL2 participated on our site, such as Anchoring fibril formation, Assembly of collagen fibrils and other multimeric structures, Collagen biosynthesis and modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Anchoring fibril formation
BMP1A; TLL1; BMP1; BMP1B; TLL2
Assembly of collagen fibrils and other multimeric structures
COL4A5; COL8A1; CTSL1; COL4A3; COL1A1; PLEC; COL5A2; BMP1A; COL8A1A; MMP20
Collagen biosynthesis and modifying enzymes
TLL1; LEPREL1; COL25A1; COL11A1B; COL1A2; COL28A1A; COL1A1; COL19A1; COL9A3; TLDC2
Collagen formation
PCOLCE2; EMID2; COL3A1; SERPINH1; PCOLCE2B; BMP1B; COL5A2; COL28A1A; CD151; PCOLCEA
Crosslinking of collagen fibrils
LOXL4; PCOLCE; BMP1; LOXL2; LOXL3; BMP1A; BMP1B; LOX; ABHD1; TLL1
Degradation of the extracellular matrix
CTRB1; CTSS; ADAMTS4; MMP13; MMP10; ADAM8; ADAM8A; COL25A1; EMID2; MMP20
Extracellular matrix organization
COL4A3; CAPNS1; F11R.2; COL4A4; LTBP4; COL6A3; COL9A1A; LOXL3; ADAMTS8; FBN1

Protein Function

TLL2 has several biochemical functions, for example, calcium ion binding, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TLL2 itself. We selected most functions TLL2 had, and list some proteins which have the same functions with TLL2. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein CRB1; PCDH2AB2; PVALB5; MYL10; MMP30; CAMKK2; ANKRD5; MYLPFB; S100G; C1S
Function metalloendopeptidase activity
Related Protein NLN; MMP26; C6AST4; ADAMTS5; ADAMTS16; MMP30; PHEX; C6AST1; ADAM15; ADAMTS15A
Function zinc ion binding
Related Protein NR1H3; CXXC1; PRKCBB; ESR1; C6AST4; PHF17; ADAMTS15A; ZNF205; PYGO2; TIMM10

TLL2 Related Articles

Cvjeticanin, B; Prutki, M; et al. Possible target for preventing fibrotic scar formation following acute myocardial infarction. MEDICAL HYPOTHESES 83:656-658(2014).
Malecaze, F; Massoudi, D; et al. Upregulation of Bone Morphogenetic Protein-1/Mammalian Tolloid and Procollagen C-Proteinase Enhancer-1 in Corneal Scarring. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:-(2014).