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TLL2

  • Official Full Name

    tolloid-like 2

  • Synonyms

    TLL2;tolloid-like 2;11844;ENSG00000095587;10q23-q24;KIAA0932, MGC133312, MGC133313;tolloid-like protein 2;tolloid-like protein 2;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TLL2-3255H Recombinant Human TLL2, His-tagged E.coli His 67-154aa
Human TLL2-1048HCL Recombinant Human TLL2 293 Cell Lysate HEK293 N/A
Human TLL2-3256H Recombinant Human TLL2 Protein, GST-tagged Wheat Germ GST 1-1015
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TLL2 Related Articles

TLL2 involved in several pathways and played different roles in them. We selected most pathways TLL2 participated on our site, such as Anchoring fibril formation, Assembly of collagen fibrils and other multimeric structures, Collagen biosynthesis and modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Anchoring fibril formationTLL1;BMP1;BMP1B;TLL2;BMP1A
Assembly of collagen fibrils and other multimeric structuresCOL5A3A;COL6A2;COL11A1B;LOXL2;COL2A1;COL8A2;BMP1A;DST;PLEC
Collagen biosynthesis and modifying enzymesCOL28A1D;COL1A1;COL25A1;COL10A1;BMP1;LEPREL2;COL1A2;COL8A1A;PRP
Collagen formationCOL8A1;COL4A5;EMID2;COL10A1A;PCOLCEA;PCOLCE2B;COL17A1;COL9A3;COL17A1A
Crosslinking of collagen fibrilsTLL1;LOXL2;BMP1A;LOX;LOXL4;BMP1B;BMP1;ABHD1;LOXL3
Degradation of the extracellular matrixCTSL1;CTSS;MMP10;CTS7;TIMP2A;ACAN;ADAM9;ADAMTS1;TLL2
Extracellular matrix organizationMFAP5;DMD;COL16A1;COL10A1A;ADAMTS1;TIMP2A;FURINA;COL25A1;COL17A1

TLL2 has several biochemical functions, for example, calcium ion binding, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TLL2 itself. We selected most functions TLL2 had, and list some proteins which have the same functions with TLL2. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingCASQ1;DSG3;MYL6;ANXA5B;S100S;KCNIP4;MCFD2;SYTL1;SLIT1
metalloendopeptidase activityADAMTS16;UQCRC2;BMP1;ADAM12;MMP7;TLL2;MMP14B;OMA1;MMP23BB
zinc ion bindingNHLRC1;DTX1;RNF44;S100A6;TRIM17;ZDHHC5A;TAF15;CAPNS2;FBXO11

TLL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLL2.

Cvjeticanin, B; Prutki, M; et al. Possible target for preventing fibrotic scar formation following acute myocardial infarction. MEDICAL HYPOTHESES 83:656-658(2014).
Malecaze, F; Massoudi, D; et al. Upregulation of Bone Morphogenetic Protein-1/Mammalian Tolloid and Procollagen C-Proteinase Enhancer-1 in Corneal Scarring. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:-(2014).
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