TLL2
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Official Full Name
tolloid-like 2 -
Synonyms
TLL2;tolloid-like 2;11844;ENSG00000095587;10q23-q24;KIAA0932, MGC133312, MGC133313;tolloid-like protein 2;tolloid-like protein 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TLL2-3255H | Recombinant Human TLL2, His-tagged | E.coli | Human | His | 67-154aa | |
| TLL2-1048HCL | Recombinant Human TLL2 293 Cell Lysate | HEK293 | Human | Non |
|
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| TLL2-3256H | Recombinant Human TLL2 Protein, GST-tagged | Wheat Germ | Human | GST | 1-1015 |
|
| Tll2-453M | Recombinant Mouse Tll2 protein, His&Myc-tagged | E.coli | Mouse | His&Myc | 146-346a.a. |
|
| Tll2-785M | Recombinant Mouse Tll2 protein, His-tagged | E.coli | Mouse | His | 146-346a.a. |
|
Involved Pathway
TLL2 involved in several pathways and played different roles in them. We selected most pathways TLL2 participated on our site, such as Anchoring fibril formation,Assembly of collagen fibrils and other multimeric structures,Collagen biosynthesis and modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Anchoring fibril formation | TLL1,BMP1,BMP1B,BMP1A |
| Collagen formation | MMP13,CD151,COL19A1,COL8A1A,PCOLCE2,LOXL3,MMP20,COL25A1,SERPINH1,COL4A4 |
| Collagen biosynthesis and modifying enzymes | COL6A2,ADAMTS3,COL1A2,COL8A1,PCOLCEA,PPIB,SERPINH1A,COL1A1,COL5A1,COL9A3 |
| Assembly of collagen fibrils and other multimeric structures | COL4A3,BMP1A,TLL1,COL10A1A,PCOLCE,PLEC,COL6A2,COL8A1,CTSL1,COL2A1 |
| Crosslinking of collagen fibrils | LOXL4,PCOLCE,BMP1A,LOXL3,ABHD1,LOX,LOXL2,BMP1,TLL1,BMP1B |
| Degradation of the extracellular matrix | ELANE,ADAMTS1,CTS7,ADAM8A,ADAMTS4,ADAMTS18,LOC100686744,MGC174857,ADAM15,FURINB |
| Extracellular matrix organization | LOXL4,CEACAM8,COL3A1,DAG1,COL5A3B,KLK7,COL6A2,LTBP2,MGC174857,COL4A3 |
Protein Function
TLL2 has several biochemical functions, for example, calcium ion binding,metalloendopeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TLL2 itself. We selected most functions TLL2 had, and list some proteins which have the same functions with TLL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | TRAF4B,MT1B,RNF180,LIMCH1,TRIM21,ZCCHC17,GATA2B,RNF181,VAT1L,CAD |
| calcium ion binding | TPO,EFCC1,SERPINB1A,MYLPFB,FBN1,EFEMP2B,PCDHA10,CSN2,RET,LETM1 |
| metalloendopeptidase activity | PITRM1,C6AST3,MMP9,ADAM17,PAPPAA,MMP10,ADAMTS2,ECEL1,MMP17,ADAMTS13 |
Interacting Protein
TLL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLL2.
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References
- Cvjeticanin, B; Prutki, M; et al. Possible target for preventing fibrotic scar formation following acute myocardial infarction. MEDICAL HYPOTHESES 83:656-658(2014).
- Malecaze, F; Massoudi, D; et al. Upregulation of Bone Morphogenetic Protein-1/Mammalian Tolloid and Procollagen C-Proteinase Enhancer-1 in Corneal Scarring. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:-(2014).
