tumor protein p53 regulated apoptosis inducing protein 1
This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
TP53AIP1; tumor protein p53 regulated apoptosis inducing protein 1; p53-regulated apoptosis-inducing protein 1; p53AIP1
TP53AIP1 involved in several pathways and played different roles in them. We selected most pathways TP53AIP1 participated on our site, such as p signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TP53AIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
TP53AIP1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by TP53AIP1 itself. We selected most functions TP53AIP1 had, and list some proteins which have the same functions with TP53AIP1. You can find most of the proteins on our site.
Related Protein EEF2KMT; TMEM258; AQP11; CNNM2; AMMECR1; TMCO7; C1orf123; TMEM52B; HID1B; TMEM14CA
TP53AIP1 Related Articles
De la Rosa, AJ; Gomez, MA; et al. CD95 Signaling in Cancer Treatment. CURRENT PHARMACEUTICAL DESIGN 20:2809-2818(2014).
Allen, JE; Krigsfeld, G; et al. Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects. SCIENCE TRANSLATIONAL MEDICINE 5:-(2013).