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TRIM17

Official Full Name

tripartite motif containing 17
Overview

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein is expressed almost exclusively in the testis, but its function is unknown. Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms

TRIM17; tripartite motif containing 17; RNF16, tripartite motif containing 17; E3 ubiquitin-protein ligase TRIM17; RBCC; ring finger protein 16; RING finger protein terf; terf; testis RING finger protein; RNF16; TRIM 17; Tripartite motif protein 17; tripartite motif-containing 17; tripartite motif-containing protein 17;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TRIM17-1823HCL	Recombinant Human TRIM17 cell lysate		N/A	Inquiry
Mouse	TRIM17-17345M	Recombinant Mouse TRIM17 Protein	Mammalian Cell	His	Inquiry
Mouse	TRIM17-9594M-B	Recombinant Mouse TRIM17 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	TRIM17-9594M	Recombinant Mouse TRIM17 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	TRIM17-6271R	Recombinant Rat TRIM17 Protein	Mammalian Cell	His	Inquiry
Rat	TRIM17-5928R	Recombinant Rat TRIM17 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	TRIM17-5928R-B	Recombinant Rat TRIM17 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
TRIM17 Related Articles

TRIM17 involved in several pathways and played different roles in them. We selected most pathways TRIM17 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytokine Signaling in Immune system	IFI27;CSH1;TRIM26;HBEGF;IRF2;PAQR3A;CISH;CASPB;CSHL1
Immune System	POLR3H;BTR29;OSBPL1A;TRIM17;KIR2DS2;UBE2F;TPP2;KIF26A;KIFAP3
Interferon Signaling	GBP2;IFITM2;ISG20;IFIT14;TRIM26;BST2;TRIM17;IFI35;IRF9
Interferon gamma signaling	TRIM14;FCGR1B;TRIM29;TRIM68;IRF6;TRIM6;HLA-DQB2;TRIM45;TRIM31

TRIM17 has several biochemical functions, for example, ligase activity, protein binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM17 itself. We selected most functions TRIM17 had, and list some proteins which have the same functions with TRIM17. You can find most of the proteins on our site.

Function	Related Protein
ligase activity	RNF34;ZNRF2;TTC3;SHPRH;RNF182;TRIM23;PCXA;FPGS;UBR3
protein binding	PIK3CB;CARD9;TSN;PRMT8;LMO4;VASP;ARVCF;QKI;SOCS2
protein binding, bridging	SLC9A1;PPP4R2;CRADD;COL8A2;FSCN2;COL1A2;SPRR1B;FSCN3;PSMC6
ubiquitin-protein transferase activity	TRIP12;RNF31;SIAH2L;ITCHA;NLRC4;UBA7;NHLRC1;RNF4;CMTM2A
zinc ion binding	TCEA1;MATR3L;MLL5;TIMM10;ZFYVE19;CPA2;AGBL2;ALKBH8;RNF125

TRIM17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM17 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM17.

TRIM39; b4dyc6_human; HSP90AB1; MLF1; q53fc7_human; HSP90AB1; NUDCD3; q96be0_human; AARSD1; CACYBP; NUDC; UBE2D1; MNAT1; UBE2D3; UBE2H

Kao, TH; Liao, HF; et al. Ectopic DNMT3L Triggers Assembly of a Repressive Complex for Retroviral Silencing in Somatic Cells. JOURNAL OF VIROLOGY 88:10680-10695(2014).

Smith, S; Gabhann, JN; et al. Estrogen Receptor alpha Regulates Tripartite Motif-Containing Protein 21 Expression, Contributing to Dysregulated Cytokine Production in Systemic Lupus Erythematosus. ARTHRITIS & RHEUMATOLOGY 66:163-172(2014).