TRIM25 Protein, tripartite motif containing 25


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Official Full Name tripartite motif containing 25
Background TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family, and functions as a ubiquitin ligase. Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demo
Synonyms TRIM25; tripartite motif containing 25; tripartite motif containing 25 , zinc finger protein 147 (estrogen responsive finger protein) , ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; EFP; RNF147; RING finger protein 147; zinc finger protein-147; tripartite mo
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM25-788HCL Recombinant Human TRIM25 293 Cell Lysate HEK293 N/A
    Mouse TRIM25-17350M Recombinant Mouse TRIM25 Protein Mammalian Cell His
    Zebrafish TRIM25-10521Z Recombinant Zebrafish TRIM25 Mammalian Cell His

    TRIM25 involved in several pathways and played different roles in them. We selected most pathways TRIM25 participated on our site, such as NF-kappa B signaling pathway, RIG-I-like receptor signaling pathway, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    NF-kappa B signaling pathway PRKCQ; BCL2A1; PRKCB; BLNK; LCK; CCL4L1; TICAM2; TRADD; RIPK1; CARD11
    RIG-I-like receptor signaling pathway PL10; IFNW1; TANK; PIN1; TBK1; ATG5; DDX58; TRADD; MAVS; TBKBP1

    TRIM25 has several biochemical functions, for example, acid-amino acid ligase activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM25 itself. We selected most functions TRIM25 had, and list some proteins which have the same functions with TRIM25. You can find most of the proteins on our site.

    Function Related Protein
    acid-amino acid ligase activity RAG1; TRIM25; RNF41; UBA3
    poly(A) RNA binding POP1; RBM5; AKAP8; ACTN4; RPGR; CCDC86; CSDA; PEG10; RIMS2; CNBP
    protein binding UROD; EIF4EBP3L; AMIGO2; CCR1; MRPL41; KLC4; CSF1; OSTA; COPS2; ABTB1
    transcription factor activity, sequence-specific DNA binding RBPJA; ATF6; HOMEZA; ZNF711; KLF9; TARDBP; BATF; GPBP1L1; ZFP82; ZNF207
    ubiquitin protein ligase activity involved in ERAD pathway RNF185; STUB1; RNF5; PARK2; TRIM25; TMEM129; SYVN1; AMFR
    zinc ion binding JUB; KIAA0913; USP20; ZFML; MATR3L; TAF15; MLL1; HDAC6; USP45; NR1I2

    TRIM25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM25 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM25.

    DDX58; NS; f1ba49_9viru; NS1; NS1; NS1; NS1; XRCC3; IGF1R; APC

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