trim25
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  • Official Full Name
  • tripartite motif containing 25
  • Background
  • TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family, and functions as a ubiquitin ligase. Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demo
  • Synonyms
  • TRIM25; tripartite motif containing 25; tripartite motif containing 25 , zinc finger protein 147 (estrogen responsive finger protein) , ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; EFP; RNF147; RING finger protein 147; zinc finger protein-147; tripartite mo
Cat.#:TRIM25-17350MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TRIM25 Protein
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Cat.#:TRIM25-10521ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TRIM25
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Cat.#:TRIM25-788HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TRIM25 293 Cell Lysate
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Involved Pathway

TRIM25 involved in several pathways and played different roles in them. We selected most pathways TRIM25 participated on our site, such as NF-kappa B signaling pathway, RIG-I-like receptor signaling pathway, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM25 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
NF-kappa B signaling pathway
GADD45B; XIAP; PTGS2; CD14; IKBKB; UBE2I; LBP; TNFRSF13C; MAP3K14; PIAS4
RIG-I-like receptor signaling pathway
IFNA13; IFNA16; MAPK14B; IKBKE; DDX3X; TANK; IFNA10; IFNA21; NFKBIAB; IL8L2
Influenza A
HLA-DRB4; SOCS3; Ifna11; NXT2; HLA-DOA; IFNA16; TLR7; AKT1; MAPK8; IL8L2

Protein Function

TRIM25 has several biochemical functions, for example, acid-amino acid ligase activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM25 itself. We selected most functions TRIM25 had, and list some proteins which have the same functions with TRIM25. You can find most of the proteins on our site.
Function
Related Protein
Function acid-amino acid ligase activity
Related Protein RNF41; RAG1; TRIM25; UBA3
Function poly(A) RNA binding
Related Protein RPS9; RPF2; SNRPD1; CCT4; G3BP2; ISY1; DUS3L; RPS17L; BZW1; RPUSD3
Function protein binding
Related Protein PRIMPOL; PPIC; RAB26; BATF3; RGS14; WDR20; CD3E; CTF1; GRASP; ADAMTSL5
Function transcription factor activity, sequence-specific DNA binding
Related Protein BRD8; STAT4; SHOX; ZNF334; PTTG1; GPBP1; PPARAA; KDM3A; NFIC; DBPA
Function ubiquitin protein ligase activity involved in ERAD pathway
Related Protein TRIM25; RNF5; PARK2; RNF185; SYVN1; STUB1; AMFR; TMEM129
Function zinc ion binding
Related Protein WHSC1; ZNF276; NR2F6; MARCH9; LMO7B; GCM1; RNF24; LMO4A; AJUBA; ZFAND2B

Interacting Protein

TRIM25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM25 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM25.
DDX58; NS; f1ba49_9viru; NS1; NS1; NS1; NS1; XRCC3; IGF1R; APC