TRIM27

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TRIM27

Official Full Name Tripartite Motif Containing 27
Background This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a;RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It;interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in;the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the;RET gene product has been shown to result in production of the ret transforming protein.
Synonyms TRIM27; tripartite motif containing 27; RFP; RNF76; zinc finger protein RFP; OTTHUMP00000029314; OTTHUMP00000107284; ret finger protein; RING finger protein 76; RFP transforming protein; tripartite motif-containing 27; tripartite motif protein TRIM27; tripartite motif-containing protein 27
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM27-687H Recombinant Human TRIM27 Protein, His-tagged E.coli His
    Human TRIM27-786HCL Recombinant Human TRIM27 293 Cell Lysate HEK293 N/A
    Mouse TRIM27-17352M Recombinant Mouse TRIM27 Protein Mammalian Cell His
    Rhesus Macaque TRIM27-4959R Recombinant Rhesus monkey TRIM27 Protein, His-tagged Mammalian Cell His
    Chicken TRIM27-2375C Recombinant Chicken TRIM27 Mammalian Cell His
    Chicken TRIM27-3719C Recombinant Chicken TRIM27 Mammalian Cell His

    TRIM27 involved in several pathways and played different roles in them. We selected most pathways TRIM27 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    TRIM27 has several biochemical functions, for example, DNA binding, ligase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM27 itself. We selected most functions TRIM27 had, and list some proteins which have the same functions with TRIM27. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding SMARCB1; CXXC1A; TERF1; ZBTB5; SSH2; RBPJB; E2F1; ZNF493; ZFAND3; ZBTB25
    ligase activity UBE2D1A; PARK2; PIAS3; ARIH1; HERC6; CDC34A; PELI1; XIAP; RNF168; TRIM62
    metal ion binding CD209A; SIRT4; Atp8a2; MARCH6; ZBTB4; CSHL1; RXRAA; VAV1; SLC2A4RG; NUDT13
    nucleic acid binding RBM4B; CPEB1A; PRDM13; RNASEL4; JAZF1A; GRSF1; ATF7B; HELQ; SPRN; RBM12B1
    protein binding STAU1; GNA14; SLC16A3; AJUBA; SLC22A2; ACAT2; P4HB; NAMPT; KLC4; DDX55
    transmembrane receptor protein tyrosine kinase activity EPHA2A; ERBB4; NTRK3A; INSRR; ERBB3B; INSRA; KIT; IGF1RB; FGFR1B; EPHB4A
    ubiquitin-protein transferase activity PDZRN3B; BIRC3; RNF144AA; FBXO9; RNF151; PRP19; UBE2D3; FBXW2; FBXO40.1; RNF213
    zinc ion binding NR5A2; TP53; ZDHHC5A; RNF130; TRIM44; MNAT1; BARD1; WT1; ADAMTS5; LNX2

    TRIM27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM27 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM27.

    NEDD9; JOSD1; PPP1R18; ZNF417; TUFT1

    Oh, Y; Chung, KC; et al. UHRF2, a Ubiquitin E3 Ligase, Acts as a Small Ubiquitin-like Modifier E3 Ligase for Zinc Finger Protein 131. JOURNAL OF BIOLOGICAL CHEMISTRY 288:9102-9111(2013).
    Horio, M; Kato, T; et al. Expression of RET finger protein predicts chemoresistance in epithelial ovarian cancer. CANCER MEDICINE 1:218-229(2012).

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