TRIM29

  • Official Full Name

    tripartite motif containing 29

  • Overview

    The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.

  • Synonyms

    TRIM29;tripartite motif containing 29;tripartite motif-containing protein 29;ataxia telangiectasia group D associated protein;ATDC;FLJ36085;tripartite motif protein TRIM29;tripartite motif-containing 29;ataxia telangiectasia group D-associated pro

Recombinant Proteins

  • Mouse
  • Rhesus macaque
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • DDK
  • Myc
  • Flag
  • Avi
  • Fc

    Involved Pathway

    TRIM29 involved in several pathways and played different roles in them. We selected most pathways TRIM29 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM29 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Immune System CRTAM,TXNIPA,ASB8,CLEC4D,CD300LF,LILRB2,UBR2,CD96,SIRPB1,CTSD
    Interferon Signaling GBP6,TRIM5,TRIM45,GBP1,HERC5,IFI27,IRF6,EIF4G2A,IRF2,IFIT10
    Interferon gamma signaling TRIM68,TRIM46,IRF6,IFI30,GBP6,TRIM3,TRIM26,OASL,TRIM38,TRIM5
    Cytokine Signaling in Immune system NRG3,TRIM46,IL17RD,NRG4,TNFRSF13C,HBEGF,CSHL1,EDARADD,HERC5,UBE2L6

    Protein Function

    TRIM29 has several biochemical functions, for example, p53 binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM29 itself. We selected most functions TRIM29 had, and list some proteins which have the same functions with TRIM29. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, sequence-specific DNA binding ZNF26,POU4F3,POU3F1,TCF7L2,RAB11FIP4A,ZNF821,TRP53,ZKSCAN1,HOMEZB,RELB
    p53 binding ZMAT3,EP300,CDKN2A,CDKN2AIP,CHD8,MDM2,SIRT1,USP10,RNF20,BANP
    protein binding EIF2AK3,CABLES1,KRT79,TRIM16,MED10,MAPK15,PGM1,COQ7,FAM46D,MRPL49
    zinc ion binding ADAMTS18,NR1I2,MPI,PTER,CPN1,NR2F6A,CPXM2,ADAM28,RFPL4,TRIM4

    Interacting Protein

    TRIM29 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM29 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM29.

    GOLGA2;CEP70;LZTS2;MAD1L1;DVL2

    Resources

    References

    • Kanno, Y; Watanabe, M; et al. TRIM29 as a novel prostate basal cell marker for diagnosis of prostate cancer. ACTA HISTOCHEMICA 116:708-712(2014).
    • Huang, WB; Williamson, SR; et al. Novel markers of squamous differentiation in the urinary bladder. HUMAN PATHOLOGY 44:1989-1997(2013).

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