trio
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  • Official Full Name
  • TrioB6
  • Background
  • Triple functional domain protein is a protein that in humans is encoded by the TRIO gene. TRIO (gene) has been shown to interact with Filamin and RHOA.
  • Synonyms
  • trio;0368/10;0959/14;1372/03;1386/06;BEST:LD36950;CG18214;CG9208;Dmel\CG18214;DTrio;l(3)036810;l(3)6D104;l(3)S036810;l(3)S095914;l(3)S137203;l(3)S138606;l(3)S[1372/3];l(3)S[1386/06];l(3)trio;M89;UNC-73/Trio;CG18214 gene product from transcript CG18214-RA;CG18214-PA;CG18214-PB;CG18214-PC;CG18214-PD;CG18214-PE;CG18214-PF;trio-PA;trio-PB;trio-PC;trio-PD;trio-PE;trio-PF;
Cat.#:TRIO-17404MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TRIO Protein
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Involved Pathway

TRIO involved in several pathways and played different roles in them. We selected most pathways TRIO participated on our site, such as Axon guidance, Cell death signalling via NRAGE, NRIF and NADE, DCC mediated attractive signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
CSNK2A2; DUSP4; SEMA3D; CDK5R1B; PLXNA3; CNTN1; SCN3B; TRPC4; SEMA3E; PTPRA
Cell death signalling via NRAGE, NRIF and NADE
OBSCN; ARHGAP4A; ITSN1; ARHGEF17; FGD2; ARHGAP4; AKAP13; ITGB3BP; CASP2; FGD4A
DCC mediated attractive signaling
NTN1B; TRIO; NTN1A; DCC; DOCK1
Developmental Biology
IL17RD; ACTR2B; EPHB4A; KIF4A; KIF4; NRP2; ST8SIA2; CARM1; DUSP10; EFNA1B
G alpha (12/13) signalling events
ABR; ARHGEF1A; ITSN1; NET1; ADRA1B; RHOC; RHOGA; TIAM2; DCLRE1B; GNA13
G alpha (q) signalling events
OXTRL; ANXA1C; DGKB; QRFP; APPB; CHRM3; FPR-RS4; PROK2; LTB4R; AGT
GPCR downstream signaling
ARHGEF1A; GPR65; RGS1; SOUL4; ARHGEF25; FPR-RS3; RHOB; TAS2R3; CCR7; OPN4
Gastrin-CREB signalling pathway via PKC and MAPK
ANXA1; OPN4.1; RASGRP2; ANXA1B; LTB4R; TAC1; RGS21; GCGB; TAE1; QRFP

Protein Function

TRIO has several biochemical functions, for example, ATP binding, Rho guanyl-nucleotide exchange factor activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIO itself. We selected most functions TRIO had, and list some proteins which have the same functions with TRIO. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein UBA6; SPG7; KLHL8; CLP1; ZNF143B; MAP2K4; ACVR1C; CCT5; LIMK1A; MAP3K10
Function Rho guanyl-nucleotide exchange factor activity
Related Protein AKAP13; DNMBP; ARHGEF9B; MCF2L; NET1; PLEKHG2; FARP1; ARHGEF11; ARHGEF7A; FGD2
Function enzyme binding
Related Protein YES1; CYP1A1; ZNF346; TNKS2; LGALS9; SORT1; MAT2B; AKIRIN2; IQCB1; LAMP2
Function guanyl-nucleotide exchange factor activity
Related Protein SPATA13; FGD6; ARFGEF2; RABIF; TBC1D10A; RASGRF2B; TRIO; ARHGEF19; RANGRF; TBXAS1
Function kinase activity
Related Protein SMG1; BMPR2B; DCKL1B; CKMB; FGGY; NEK5; PKM; PRKAB1B; PKMYT1; Aatk
Function nucleotide binding
Related Protein EEF2A.2; MRPL23; SRSF1; CPEB2; GC2; SFRS9; DCLK1A; SETD1B; OXSR1B; ARL4AB
Function protein kinase activity
Related Protein AURKC; TSSK1; PAK2; PRKDC; EGFRA; AKT3A; KDRL; PRKACBA; ADRBK2; IKBKB
Function protein serine/threonine kinase activity
Related Protein TSSK5; BMPR1B; STK38L; FASTK; CSNK1D; ULK1A; HIPK2; CAMK2G1; DYRK1B; CDC42BPB
Function transferase activity
Related Protein OASL1; EXT1B; STT3B; TRIOA; MARCKSB; GSTM7; GALNTL4; EPHA2A; ELOVL6L; METTL23

TRIO Related Articles

Marie, A; Holzmuller, P; et al. Anopheles gambiae salivary protein expression modulated by wild Plasmodium falciparum infection: highlighting of new antigenic peptides as candidates of An. gambiae bites. PARASITES & VECTORS 7:-(2014).
Bradshaw, NJ; Bader, V; et al. Aggregation of the Protein TRIOBP-1 and Its Potential Relevance to Schizophrenia. PLOS ONE 9:-(2014).