• Official Full Name
  • thyroid hormone receptor interactor 6
  • Background
  • This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
  • Synonyms
  • TRIP6; thyroid hormone receptor interactor 6; thyroid receptor-interacting protein 6; MGC3837; MGC4423; MGC10556; MGC10558; MGC29959; OIP1; ZRP 1; OIP-1; OPA interacting protein 1; OPA-interacting protein 1; Thyroid receptor interacting protein 6; TR-interacting protein 6; TRI6; TRIP 6; TRIP-6; TRIP6_HUMAN; ZRP-1; ZRP1; Zyxin related protein 1; Zyxin-related protein 1; OTTHUMP00000211326; thyroid hormone receptor interacting protein 6; TRIP6i2
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIP6 Protein, His/GST-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Trip6 Protein, His/GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIP6, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIP6 Protein, GST-His-tagged
Source (Host):Species:Human
Product nameRecombinant Human TRIP6 293 Cell Lysate

Involved Pathway

TRIP6 involved in several pathways and played different roles in them. We selected most pathways TRIP6 participated on our site, such as NOD-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
NOD-like receptor signaling pathway
MAPK10; IL8L2; IL18; LOC100033925; CASP8; SGUT1; BIRC3; CARD18; CASP1; MAP3K7

Protein Function

TRIP6 has several biochemical functions, for example, interleukin-1 receptor binding, kinase binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIP6 itself. We selected most functions TRIP6 had, and list some proteins which have the same functions with TRIP6. You can find most of the proteins on our site.
Related Protein
Function interleukin-1 receptor binding
Related Protein IL1A; IL37; TLR9; IL36B; IL1B; IRAK4; IL36RN; IL36A; IL1RAP; IRAK1
Function kinase binding
Related Protein WWC3; C2orf44; CAB39; PARK2; TENC1; MOBKL1A; WWC1; CDC37; BARD1; CHIA
Function poly(A) RNA binding
Related Protein HSP90AA1; MRPS21; MRPL27; TRIM28; ZCCHC17; EEF2; CTNNA1; BOP1; FAM50A; NOM1
Function protein binding
Related Protein CMTM3; CSNK1G1; BCS1L; TMEM110; SMAD9; CD200; NRL; TBC1D14; IMMT; PHF17
Function thyroid hormone receptor binding
Related Protein FUS; MED12; MED17; TRIP6; HMGN3; MED24; TAF11; NSD1; TRIP12; ZNHIT3
Function zinc ion binding
Related Protein VAT1; ZDHHC4; TRIM35-23; EWSR1; ZCCHC3; DZIP3; RNF222; PTPN1; TRIM59; FTR14

Interacting Protein

TRIP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIP6.