tuba8
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  • Official Full Name
  • tubulin, alpha 8
  • Background
  • This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families;(alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated;with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants.
  • Synonyms
  • TUBA8; tubulin, alpha 8; TUBAL2; tubulin alpha-8 chain; Alpha tubulin 8; Alpha-tubulin 8; TBA8_HUMAN; Tubulin alpha 8 chain; Tubulin alpha chain like 2; Tubulin alpha chain-like 2
Cat.#:TUBA8-17614MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TUBA8 Protein
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Cat.#:TUBA8-6360RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TUBA8 Protein
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Cat.#:TUBA8-6994CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TUBA8
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Cat.#:TUBA8-655HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TUBA8 293 Cell Lysate
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Involved Pathway

TUBA8 involved in several pathways and played different roles in them. We selected most pathways TUBA8 participated on our site, such as Phagosome, Gap junction, Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
TAP1; HLA-DOB; RAB5AA; H2-AA; HLA-DOA; TUBA3E; ATP6V1AA; M6PR; ABCB3L1; MARCO
Gap junction
GNA15.1; TUBA4A; DRD1A; DRD2L; PDGFRA; TUBA8L4; TJP1; GNA11A; TUBA8L; GNA11
Pathogenic Escherichia coli infection
ARPC5L; RHOA; ARHGEF2; TUBB6; HCLS1; TUBA3C; NCK2; ACTB; TUBA1B; TUBB1

Protein Function

TUBA8 has several biochemical functions, for example, GTP binding, GTPase activity, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBA8 itself. We selected most functions TUBA8 had, and list some proteins which have the same functions with TUBA8. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein Arf2; THG1L; ARFRP1; GIMAP4; RRAGB; GNA11; RAB30; RAC1B; TUBA8L4; RASL11A
Function GTPase activity
Related Protein RAB8A; GNG11; GPN1; EFTUD2; EEF1A1B; EIF5; ARF5; RHOD; ARF4; TUBA1L
Function structural constituent of cytoskeleton
Related Protein TUBA1B; SPTBN1; SPRR2A1; ANK1; DSP; KRT71; CTNNA2; PLS1; TUBGCP3; TUBA4L

Interacting Protein

TUBA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBA8.
IKBKG; ARRB2; HTR7; SLC38A1

TUBA8 Related Articles

Tiriveedhi, V; Banan, B; et al. Role of defensins in the pathogenesis of chronic lung allograft rejection. HUMAN IMMUNOLOGY 75:370-377(2014).
Dvorak, J; Sitorova, V; et al. Primary cilia in gastrointestinal stromal tumors. NEOPLASMA 61:305-308(2014).