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TUBA8

  • Official Full Name

    tubulin, alpha 8

  • Overview

    This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families;(alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated;with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants.
  • Synonyms

    TUBA8; tubulin, alpha 8; TUBAL2; tubulin alpha-8 chain; Alpha tubulin 8; Alpha-tubulin 8; TBA8_HUMAN; Tubulin alpha 8 chain; Tubulin alpha chain like 2; Tubulin alpha chain-like 2;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TUBA8-655HCL Recombinant Human TUBA8 293 Cell Lysate HEK293 N/A
Human TUBA8-2192H Recombinant Human TUBA8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse TUBA8-17614M Recombinant Mouse TUBA8 Protein Mammalian Cell His
Mouse Tuba8-6727M Recombinant Mouse Tuba8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TUBA8-9758M Recombinant Mouse TUBA8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TUBA8-9758M-B Recombinant Mouse TUBA8 Protein Pre-coupled Magnetic Beads HEK293
Rat TUBA8-6360R Recombinant Rat TUBA8 Protein Mammalian Cell His
Rat TUBA8-6016R-B Recombinant Rat TUBA8 Protein Pre-coupled Magnetic Beads HEK293
Rat TUBA8-6016R Recombinant Rat TUBA8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken TUBA8-6994C Recombinant Chicken TUBA8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TUBA8 Related Articles

TUBA8 involved in several pathways and played different roles in them. We selected most pathways TUBA8 participated on our site, such as Phagosome, Gap junction, Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PhagosomeCTSLA;ATP6V0CB;TLR4;THBS1;H2-AB1;HLA-DQA1;MSR1;TUBA8L;THBS2
Gap junctionPRKACA;ADCY1A;RAF1;MAPK7;GNAS;MAP2K2B;CSNK1DA;PLCB4;TUBA3A
Pathogenic Escherichia coli infectionTUBB1;RHOA;TUBA1A;WAS;OCLN;CLDN1;PRKCA;TUBA4A;TUBAL3

TUBA8 has several biochemical functions, for example, GTP binding, GTPase activity, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBA8 itself. We selected most functions TUBA8 had, and list some proteins which have the same functions with TUBA8. You can find most of the proteins on our site.

Function Related Protein
GTP bindingSEPT9B;EEF1A1L2;RAB8A;RND3;TUBB4A;GMPPB;ARL13B;EEFSEC;RAP2A
GTPase activityRAB1BB;ATL3;RAB35B;TUBA8;TUBA1L;ATL2;TUBA3E;GNAI2;GNA11B
structural constituent of cytoskeletonBFSP2;TUBGCP4;BICD1;ACTL7A;SYNM;TUBB6;TUBGCP2;TUBA3C;TUBE1

TUBA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBA8.

IKBKG; ARRB2; HTR7; SLC38A1

Tiriveedhi, V; Banan, B; et al. Role of defensins in the pathogenesis of chronic lung allograft rejection. HUMAN IMMUNOLOGY 75:370-377(2014).
Dvorak, J; Sitorova, V; et al. Primary cilia in gastrointestinal stromal tumors. NEOPLASMA 61:305-308(2014).
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