|Official Full Name||unc-13 homolog A|
|Background||This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play;important roles in neurotransmitter release at synapses. Single nucleotide polymorphisms in this gene may be;associated with sporadic amyotrophic lateral sclerosis.|
|Synonyms||UNC13A; unc-13 homolog A (C. elegans); protein unc-13 homolog A; KIAA1032; Munc13 1; Munc13-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
UNC13A involved in several pathways and played different roles in them. We selected most pathways UNC13A participated on our site, such as Synaptic vesicle cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with UNC13A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Synaptic vesicle cycle||ATP6V0E; ATP6V0B; SLC17A7; STX2; ATP6V0A2; SNAP25; NAPA; SYT1; SLC17A6; ATP6V1E2|
UNC13A has several biochemical functions, for example, SNARE binding, diacylglycerol binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UNC13A itself. We selected most functions UNC13A had, and list some proteins which have the same functions with UNC13A. You can find most of the proteins on our site.
|SNARE binding||VTI1A; VAMP2; SYT1; SEC22BA; STX1A; SEC22BB; STX7; NBAS; CCDC167; UVRAG|
|diacylglycerol binding||RASGRP1; UNC13B; UNC13A; CDIPT; RASGRP3; TRPC2; UNC13C; RASGRP2; RASGRP4|
|metal ion binding||ZFYVE28; ZC2HC1A; CD209C; ZFYVE27; ZNF839; TIMM8A2; RNF150; TRIM2A; CYP2P7; NEK11|
|protein N-terminus binding||KCNIP1; SCFD1; ATM; TP53; DCN; HAX1; CSNK2A2; SERPINB1A; NFE2; ARF6|
|protein binding||TRPV5; HSP90AA1.2; FBXO28; RAB43; DMAP1; DMC1; RAD9; NME2; VGLL4; ORAI2|
|protein domain specific binding||CEP68; ERCC1; PICK1; STAMBP; CHMP1B; ST13; CA; STMN3; SLC34A2; CNOT1|
|protein heterodimerization activity||SNX1; RRAGC; MAFGA; XBP1; TXLNG; H2AFY; BRAF; PRMT5; HIST1H2BH; GCLC|
|protein homodimerization activity||UGT1A7; SLIT2; MAPK4; UGT1A6; IKZF2; GNB2L1; BCL11A; ACVR1; CHUK; ARID3A|
|spectrin binding||ADD2; DYNC1I1; USH1C; MYO10; EPB49; UNC13A; MYO7A; PTPRN; SLC26A5; CAMSAP1L1|
|syntaxin-1 binding||VAMP3; MYO5A; SYBU; SNPH; STXBP3; RNF40; STXBP2; STXBP3A; CPLX1; CCDC167|
UNC13A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UNC13A here. Most of them are supplied by our site. Hope this information will be useful for your research of UNC13A.