Ugt1a2
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Official Full Name
UDP glucuronosyltransferase 1 family, polypeptide A2 -
Synonyms
Ugt1;UDPGT 1-2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UGT1A2-17806M | Recombinant Mouse UGT1A2 Protein | Mammalian Cells | Mouse | His |
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| UGT1A2-7703Z | Recombinant Zebrafish UGT1A2 | Mammalian Cells | Zebrafish | His |
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| RFL14948RF | Recombinant Full Length Rat Udp-Glucuronosyltransferase 1-2(Ugt1) Protein, His-Tagged | E.coli | Rat | His | Full L. Full Length of Mature Protein (28-533) |
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| RFL20550MF | Recombinant Full Length Mouse Udp-Glucuronosyltransferase 1-2(Ugt1) Protein, His-Tagged | E.coli | Mouse | His | Full L. Full Length of Mature Protein (28-533) |
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| UGT1A2-9886M | Recombinant Mouse UGT1A2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| UGT1A2-9886M-B | Recombinant Mouse UGT1A2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Ugt1a2 involved in several pathways and played different roles in them. We selected most pathways Ugt1a2 participated on our site, such as Pentose and glucuronate interconversions,Ascorbate and aldarate metabolism,Steroid hormone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ugt1a2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Drug metabolism - cytochrome P | MGST1.2,FMO3,FMO5,UGT1A3,UGT1AB,GSTT2B,MGST1.1,UGT1A6,UGT1A6A,AOX4 |
| Drug metabolism - other enzymes | UCKL1,UGT1A7C,XDH,UCK2A,NAT,UGT2B7,UPP2,UGT2A2,UPP1,UGT1A7 |
| Pentose and glucuronate interconversions | DHDHL,ALDH2,CRYL1,UGT1AB,UGT1A6A,UGT1A3,AKR1A1B,UGT2A1,UGT1A9,UGT1A7 |
| Metabolic pathways | HYI,GNS,UCKL1,ATP5C1,CBR3,GRHPR,PPAP2A,GALNT14,MTMR2,B3GALNT1 |
| Ascorbate and aldarate metabolism | UGT1A6B,UGT1AB,UGT2A2,RGN,UGT1A1,GKUP,ALDH9A1,UGT1A6,MIOX,ALDH9A1B |
| Retinol metabolism | CYP26C1,CYP26B1,CYP2C38,UGT1A6,CYP4A12A,DHRS4L2,Aldh1a7,UGT1A7C,ALDH1A2,BCO1L |
| Porphyrin and chlorophyll metabolism | UGT2A1,ALAS1,HMOX2,HCCS,UGT1A1,CP,UGT1A6,ALAD,CPOX,UGT2A3 |
| Steroid hormone biosynthesis | CYP2C38,HSD17B2,AKR1C3,CYP3A7,AKR1C2,UGT1A3,UGT1A6,CYP19A1B,STS,CYP2D10 |
| Metabolism of xenobiotics by cytochrome P | GSTM1,UGT1A7,GSTM2,UGT1A6,MGST1.2,MGST3,HSD11B1,GSTT1B,GSTA4,GSTT2 |
Protein Function
Ugt1a2 has several biochemical functions, for example, enzyme binding,glucuronosyltransferase activity,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ugt1a2 itself. We selected most functions Ugt1a2 had, and list some proteins which have the same functions with Ugt1a2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity | ZDHHC18,RNMTL1A,PFKMB,CRATA,SAT2A,LRGUK,ERBB3B,EPHB4B,UGT1A7C,PRKACAA |
| protein homodimerization activity | CPNE1,LRRFIP1,PITX2,MYOM1,TMEM173,BNIP3L,DDX1,SP100,GSTM1,AOC3 |
| protein heterodimerization activity | HIST1H2BD,BOK,GCLM,TPD52,NEFL,TP53,HIST1H3C,XBP1,MICU1,HIST1H2AA |
| retinoic acid binding | UGT1A3,CRABP1,CYP26A1,CRABP1B,LRAT,CRABP2B,CRABP2,UGT1A1,SERPINA5,CYP26B1 |
| transferase activity, transferring glycosyl groups | 4931440L10Rik,UGT5A3,GBGT1,UGT2A6,UGT2B3,UGT5A1,FT2,UGT5A4,UGT1A7C,EXT1B |
| transferase activity, transferring hexosyl groups | MGAT4C,UGT1B4,A3GALT2,UGT5A2,UGT5E1,UGT5C1,GLT6D1,UGT5G1,UGT2B3,UGT1B7 |
| glucuronosyltransferase activity | UGT5A4,UGT5D1,UGT1B5,UGT1A1,UGT2B1,UGT1A7C,UGT5G1,UGT5F1,UGT2A1,LARGE |
| enzyme binding | AKIRIN2,PTPLAD1,KDM1A,ZFP346,CAD,SLC18A1,HIST1H2AG,IL6R,TSPYL1,MSH2 |
Interacting Protein
Ugt1a2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ugt1a2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ugt1a2.
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