Ugt1a2

  • Official Full Name

    UDP glucuronosyltransferase 1 family, polypeptide A2
  • Synonyms

    Ugt1;UDPGT 1-2
Cat.# Product name Source (Host) Species Tag Protein Length Price
UGT1A2-17806M Recombinant Mouse UGT1A2 Protein Mammalian Cells Mouse His
UGT1A2-7703Z Recombinant Zebrafish UGT1A2 Mammalian Cells Zebrafish His
RFL14948RF Recombinant Full Length Rat Udp-Glucuronosyltransferase 1-2(Ugt1) Protein, His-Tagged E.coli Rat His Full L. Full Length of Mature Protein (28-533)
RFL20550MF Recombinant Full Length Mouse Udp-Glucuronosyltransferase 1-2(Ugt1) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length of Mature Protein (28-533)
UGT1A2-9886M Recombinant Mouse UGT1A2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
UGT1A2-9886M-B Recombinant Mouse UGT1A2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Ugt1a2 involved in several pathways and played different roles in them. We selected most pathways Ugt1a2 participated on our site, such as Pentose and glucuronate interconversions,Ascorbate and aldarate metabolism,Steroid hormone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ugt1a2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Drug metabolism - other enzymes UGT2B7,UCK2A,UCK2B,PNAT10,UCK1,UGT5G1,Ces2e,CYP2A6,UPP2,DPYS
    Ascorbate and aldarate metabolism GULO,ALDH3A2A,ALDH3A2,UGT2B15,ALDH7A1,UGT2A3,MIOX,UGT5G1,UGT1A6,ALDH9A1A.1
    Metabolism of xenobiotics by cytochrome P AKR7A2,ALDH3B2,ALDH1A3,UGT1A9,UGT1A4,GSTM1,UGT1AB,UGT2A2,DHDH,GSTT2
    Drug metabolism - cytochrome P GSTM1,MGST1.2,UGT1A6A,UGT2A3,FMO2,ALDH3B1,MGST2,GSTM3,GSTA,AOX3L1
    Steroid hormone biosynthesis CYP7B1,HSD3B5,HSD11B2,HSD17B12,SULT2ST3,AKR1D1,H2-KE6,COMTB,HSD17B12A,UGT1A3
    Retinol metabolism BCO1,Aldh1a7,CYP2C70,CYP2A12,CYP3A41A,RETSATL,DHRS4L2,CYP2C18,ADH2-2,UGT5G1
    Chemical carcinogenesis GSTA1,CYP2C18,CYP3A4,ADH1A,CYP3A5,ADH7,CYP2B19,CYP3A41A,CYP2C37,UGT1A9
    Porphyrin and chlorophyll metabolism FXN,ALAS2,FECH,UGT1A7C,MMAB,UGT1A6,P22,UGT1A1,COX15,EARS2
    Pentose and glucuronate interconversions GUSB,CRYL1,UGT1A1,UGT1A6,UGP2,UGT1AB,KL,UGDH,DCXR,DHDH

    Protein Function

    Ugt1a2 has several biochemical functions, for example, enzyme binding,glucuronosyltransferase activity,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ugt1a2 itself. We selected most functions Ugt1a2 had, and list some proteins which have the same functions with Ugt1a2. You can find most of the proteins on our site.

    Function Related Protein
    protein heterodimerization activity TLR1,MID1,CD3E,STX1A,CD3D,IL12A,AOC3,HIST2H3C,ATF1,HIST1H2BF
    protein homodimerization activity TIRAP,PVRL1A,FASN,DMRT2,MYPOP,SLK,KLHL7,ENO2,NKX2,HM13
    glucuronosyltransferase activity UGT5B4,UGT1A1,UGT3A2,UGT5G1,UGT5E1,UGT5C3,CSGALNACT1,UGT5F1,UGT5A2,UGT1A6
    transferase activity, transferring glycosyl groups B3GNT2A,UGT5D1,GXYLT1,B3GALTLB,DPAGT1,MGAT3A,C1GALT1,ST3GAL5L,UGT1B5,GCNT4A
    transferase activity, transferring hexosyl groups GBGT1L3,UGT5A4,GBGT1L1,UGT1B5,B4GALNT1A,UGT1B7,UGT5B6,ALG3,UGT5G1,A3GALT2
    retinoic acid binding PTGDSB,CYP26A1,LCN12,RARA,NR2F2,LRAT,UGT1A9,CRABP2B,UGT1A3,CRABP2A
    enzyme binding UGT1A6A,DNMT3L,HIST1H2AL,CCDC99,HSPA1A,CYP2A4,MAPT,ATF7,C2orf56,PLCE1
    transferase activity PTAR1,EXT1C,GM4922,PLAUA,CEPT1A,GALNT18A,COMTA,ZDHHC8B,CKBB,ZDHHC18A

    Interacting Protein

    Ugt1a2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ugt1a2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ugt1a2.

    Resources

    References

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