|Official Full Name||vacuolar protein sorting 36 homolog (S. cerevisiae)|
|Background||VPS36, VPS22 (SNF8; MIM 610904), and VPS25 (MIM 610907) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. VPS36, VPS22, and VPS25 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005|
|Synonyms||VPS36; vacuolar protein sorting 36 homolog (S. cerevisiae); C13orf9, chromosome 13 open reading frame 9 , vacuolar protein sorting 36 homolog (yeast); vacuolar protein-sorting-associated protein 36; CGI 145; Eap45; C13orf9; ELL associated protein of 45 kDa; ELL-associated protein of 45 kDa; ESCRT-II complex subunit VPS36; Vacuolar protein sorting associated protein 36; VPS36_HUMAN; ELL-associated protein, 45 kDa; CGI-145|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
VPS36 involved in several pathways and played different roles in them. We selected most pathways VPS36 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS36 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Endocytosis||RAB11FIP5; FOLR3; HSC70; EPN1; EEA1; SNX2; PIP5KL1; ADRB3; AMPH; IGF1RA|
VPS36 has several biochemical functions, for example, phosphatidylinositol-3-phosphate binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS36 itself. We selected most functions VPS36 had, and list some proteins which have the same functions with VPS36. You can find most of the proteins on our site.
|phosphatidylinositol-3-phosphate binding||SNX13; JPH2; SNX24; ZFYVE28; SESTD1; WDR45L; SNX27; LANCL2; SNX3; SH3PXD2B|
|protein C-terminus binding||PHB2; BLOC1S2; HSPB7; CTNNB1; PRDX3; SLC4A1; CEP135; RABAC1; TRIM3; PIAS4|
|protein binding||AKAP9; SMYD1; TBRG1; PLAA; DOT1L; CCDC170; CCPG1; XRCC4; AHSA2; RIC8|
|ubiquitin binding||HSPB1; UBXN2A; NEDD4; USP5; SHRPRBCK1R; NPLOC4; IWS1; BCL10; TSG101; NSFL1C|
VPS36 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS36 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS36.
GCNT1; pi3p; CDC5L; Vps25; Snf8