wdr3
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  • Official Full Name
  • WD repeat domain 3
  • Background
  • This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.
  • Synonyms
  • WDR3; WD repeat domain 3; WD repeat-containing protein 3; DIP2; FLJ12796; UTP12; dJ776P7.2 (WD repeat domain 3)
Cat.#:WDR3-18463MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse WDR3 Protein
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Cat.#:WDR3-5196RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey WDR3 Protein, His-tagged
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Cat.#:WDR3-3132CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken WDR3
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Cat.#:WDR3-9863ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish WDR3
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Involved Pathway

WDR3 involved in several pathways and played different roles in them. We selected most pathways WDR3 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ribosome biogenesis in eukaryotes
PWP2H; PWP2; XRN2; RPP30; RIOK1; POP1; DROSHA; GAR1; RRP7A; NVL

Protein Function

WDR3 has several biochemical functions, for example, poly(A) RNA binding, snoRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WDR3 itself. We selected most functions WDR3 had, and list some proteins which have the same functions with WDR3. You can find most of the proteins on our site.
Function
Related Protein
Function poly(A) RNA binding
Related Protein CCDC9; EIF1AX; DDX10; CPEB4; PPRC1; FASTKD1; PIN4; SRRT; ANKRD17; RPL29
Function snoRNA binding
Related Protein PWP2; NOP58; NUDT5; WDR3; NOP56; IMP3; NOP10; IMP4; PWP2H; UTP15

WDR3 Related Articles

Saeki, M; Egusa, H; et al. Exosome-Bound WD Repeat Protein Monad Inhibits Breast Cancer Cell Invasion by Degrading Amphiregulin mRNA. PLOS ONE 8:-(2013).
Teng, YN; Liao, MH; et al. Expression of lrwd1 in mouse testis and its centrosomal localization. INTERNATIONAL JOURNAL OF ANDROLOGY 33:832-840(2010).