wnt5b
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  • Official Full Name
  • wingless-type MMTV integration site family, member 5B
  • Background
  • The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.
  • Synonyms
  • WNT5B; wingless-type MMTV integration site family, member 5B; protein Wnt-5b; WNT-5B protein; MGC2648
Cat.#:WNT5B-207HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human WNT5B, StrepII-tagged
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Cat.#:WNT5B-773HTag:
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human WNT5B
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Cat.#:WNT5B-18574MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse WNT5B Protein
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Cat.#:Wnt5b-303MTag:
Source (Host):CHO cellsSpecies:Mouse
Product nameRecombinant Mouse Wnt5b
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Cat.#:WNT5B-3289CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken WNT5B
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Cat.#:WNT5B-8578ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish WNT5B
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Cat.#:WNT5B-1478CTag:His/T7
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle WNT5B protein, His & T7-tagged
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Cat.#:WNT5B-291HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human WNT5B 293 Cell Lysate
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Cat.#:WNT5B-292HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human WNT5B 293 Cell Lysate
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Involved Pathway

WNT5B involved in several pathways and played different roles in them. We selected most pathways WNT5B participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT5B were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Wnt signaling pathway
WNT11R; TBL1X; PRKACB; WNT11B; CUL1B; NLK2; CTBP2A; RAC3A; PPP3R2; AXIN2
Hedgehog signaling pathway
WNT4A; FBXW11; FBXW11A; SHHB; WNT8B; IHHA; CSNK1A1L; WNT6; WNT4; PRKACBB
Hippo signaling pathway
WNT4; TCF7L2; CDH1; FZD8; TGFB3; AREG; LLGL2; TEAD3; FZD2; GLI2
Signaling pathways regulating pluripotency of stem cells
WNT3; BMPR1B; LHX5; PIK3CD; IL6ST; RAF1; AXIN2; FZD6; PIK3CG; FZD8
Melanogenesis
GNAS; TCF7L2; NRAS; GSK3AA; WNT3; MITFB; CAMK2B; TYR; GNAI3; POMC
HTLV-I infection
HLA-DOB; CRTC1; TRP53; PPP3R1; CCND2; ZFP36; WNT2B; ANAPC7; MAP3K14; TGFBR2
Pathways in cancer
CXCR4; PRKCA; DAPK3; VEGFB; FGFR1; IGF1; ARNT2; FGF1; MET; WNT10B
Proteoglycans in cancer
HPSE; TLR2; WNT7B; CAV1; PTPN11; NUDT16L1; PTPN6; CCND1; ROCK2; MAPK13
Basal cell carcinoma
FZD1; FZD6; TRP53; WNT9A; DVL3; FZD7; LEF1; WNT8A; GLI3; GSK3B

Protein Function

WNT5B has several biochemical functions, for example, frizzled binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT5B itself. We selected most functions WNT5B had, and list some proteins which have the same functions with WNT5B. You can find most of the proteins on our site.
Function
Related Protein
Function frizzled binding
Related Protein WNT10B; WNT9B; RNF43; RSPO3; WNT7AA; WNT4B; MYOC; ZNRF3; DVL3A; CTHRC1
Function receptor binding
Related Protein UTS2; FGF18B; EPB49; CNTFR; LTB; HILPDA; GDNF; RCHY1; MCHR1; CROT

Interacting Protein

WNT5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT5B here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT5B.
APPBP2

WNT5B Related Gene Family

WNT