WNT7A Protein, wingless-type MMTV integration site family, member 7A


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Official Full Name wingless-type MMTV integration site family, member 7A
Background This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
Synonyms WNT7A; wingless-type MMTV integration site family, member 7A; protein Wnt-7a; proto oncogene Wnt7a protein; proto-oncogene Wnt7a protein; px; tw; Wnt-7a; AI849442
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human WNT7A-208H Recombinant Human WNT7A, StrepII-tagged Human Cell Strep II
    Human WNT7A-278H Recombinant Human wingless-type MMTV integration site family, member 7A, His-tagged E.coli His
    Human WNT7A-289HCL Recombinant Human WNT7A 293 Cell Lysate HEK293 N/A
    Human WNT7A-42H Recombinant Human WNT7A Protein HEK293 N/A
    Human WNT7A-898H Recombinant Human WNT7A CHO N/A
    Mouse WNT7A-18576M Recombinant Mouse WNT7A Protein Mammalian Cell His
    Rhesus Macaque WNT7A-5219R Recombinant Rhesus monkey WNT7A Protein, His-tagged Mammalian Cell His
    Chicken WNT7A-5865C Recombinant Chicken WNT7A Mammalian Cell His

    WNT7A involved in several pathways and played different roles in them. We selected most pathways WNT7A participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT7A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway WNT4; CCND2; RAC3B; PPP3R1; PRKACBA; CSNK1A1L; VANGL2; CCND1; WNT6; NKD2B
    Hedgehog signaling pathway GSK3B; WNT10B; GSK3AA; WNT11B; WNT2B; DHH; CSNK1DB; WNT1; CSNK1DA; IHH
    Hippo signaling pathway PARD3; AMH; WNT16; DLG1; ITGB2; BIRC5; SERPINE1; TEAD1; LATS2; GDF6
    Signaling pathways regulating pluripotency of stem cells FZD1; RAF1; AKT1; SMARCAD1; PIK3CG; MAPK12; SMAD9; ID3; WNT8B; FGFR2
    HTLV-I infection SPI1; NFATC2; NFATC1; EGR1; CD3G; NFYB; ATF4; IL1R1; CANX; WNT9A
    Pathways in cancer BIRC3; TGFB2; PIK3R3; CBLB; PLCG1; TRAF3; LPAR4; RUNX1; FZD9; BCL2
    Proteoglycans in cancer CBLB; FZD5; HPSE2; MRAS; IGF1; CBL; TWIST2; HSPG2; PIK3R1; NUDT16L1
    Basal cell carcinoma FZD2; TP53; PTCH1; WNT1; FZD1; WNT8B; DVL3; WNT9B; HHIP; WNT4

    WNT7A has several biochemical functions, for example, cytokine activity, frizzled binding, receptor agonist activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT7A itself. We selected most functions WNT7A had, and list some proteins which have the same functions with WNT7A. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity AREG; TNFSF8; TNFSF9; IFNA6; IL36A; C1QTNF4; OSM; IFNA16; GDF5; IL8L2
    frizzled binding SDCBP; RSPO3; WNT4; WNT8A; WNT5B; WNT2BA; WNT9B; WNT16; DVL3; WNT3A
    receptor agonist activity WNT10B; GREM1; NODAL; WNT2; CXCL13; WNT7A; SFRP2; VEGFA; GAS6; WNT5A
    receptor binding NRG1; CD160; CD86; TYROBP; F7; TNFSF4; PKD2; PTK2BB; GSTM7; PEX14

    WNT7A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT7A here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT7A.

    WIF1; STRN4

    Tsai, HL; Deng, WP; et al. Wnts Enhance Neurotrophin-Induced Neuronal Differentiation in Adult Bone-Marrow-Derived Mesenchymal Stem Cells via Canonical and Noncanonical Signaling Pathways. PLOS ONE 9:-(2014).
    Yamada, T; Hasegawa, S; et al. Wnt/beta-Catenin and Kit Signaling Sequentially Regulate Melanocyte Stem Cell Differentiation in UVB-Induced Epidermal Pigmentation. JOURNAL OF INVESTIGATIVE DERMATOLOGY 133:2753-2762(2013).


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