ZFYVE16 Protein, zinc finger, FYVE domain containing 16


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Official Full Name zinc finger, FYVE domain containing 16
Background The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is;characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of;the molecule (Seet et al., 2004 (PubMed 14613930)).
Synonyms ZFYVE16; zinc finger, FYVE domain containing 16; zinc finger FYVE domain-containing protein 16; endofin; KIAA0305; PPP1R69; protein phosphatase 1; regulatory subunit 69; B130024H06Rik; B130031L15; DKFZp686E13162; mKIAA0305; AI035632; Endosomal associated FYVE domain protein; Endosome associated FYVE domain protein; OTTMUSP00000029589; RGD1564784; Zinc finger FYVE domain containing protein 16; OTTHUMP00000135318; OTTHUMP00000222226; OTTHUMP00000222227; endosome-associated FYVE domain protein; endosome-associated FYVE-domain protein; protein phosphatase 1, regulatory subunit 69
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ZFYVE16-1979HCL Recombinant Human ZFYVE16 cell lysate N/A
    Human ZFYVE16-3804H Recombinant Human ZFYVE16, GST-tagged E.coli GST
    Mouse ZFYVE16-19163M Recombinant Mouse ZFYVE16 Protein Mammalian Cell His

    ZFYVE16 involved in several pathways and played different roles in them. We selected most pathways ZFYVE16 participated on our site, such as Endocytosis, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZFYVE16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis IGF2R; CYTH4B; HLA-G; FAM125A; RAB11FIP3; CDC42L2; ZFYVE16; ERBB4A; SMAP2; SMAD2
    TGF-beta signaling pathway PPP2CA; TGFBR1; TGFB2; RHOAA; CUL1A; ACVR1BA; SMURF2; ID2A; PPP2R1B; GDF5

    ZFYVE16 has several biochemical functions, for example, 1-phosphatidylinositol binding, metal ion binding, phosphatidylinositol-3,4,5-trisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZFYVE16 itself. We selected most functions ZFYVE16 had, and list some proteins which have the same functions with ZFYVE16. You can find most of the proteins on our site.

    Function Related Protein
    1-phosphatidylinositol binding ZFYVE9; ZFYVE1; CCDC167; PLEKHA3; EEA1; ZFYVE16; SNAP91; EPB41; WDFY3; PLEKHA4
    metal ion binding TP63; ARL1; ZNF839; B4GALT5; PPM1LA; GTPBP8; GALNTL1; ZNF596; ZNHIT2; ZNF800B
    phosphatidylinositol-3,4,5-trisphosphate binding MYO1G; ANXA8; FERMT2; OGT; PIRT; ZFYVE1; AKT1; CYTH3; RACGAP1; RS1
    protein binding ADORA2A; FBXO6; Abcb1b; SCG2; RCAN3; NPPB; PEA15; TMEM88; LAMTOR1; VIL1
    protein transporter activity DSCR3; KPNB1; COX18; CALCR; CCT6B; FRAG1; RAB4A; AP2S1; TIMM9; ARFGAP3

    ZFYVE16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZFYVE16 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZFYVE16.

    TOM1; EEA1; PPP1CA; pepP; RNF11; Ptpn23

    Shibui, T; Kobayashi, T; et al. Isolation of cross-reacting antigen candidates by mRNA-display using a mixed cDNA library. BIOTECHNOLOGY LETTERS 30:2037-2043(2008).

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