AP1B1

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AP1B1

Official Full Name adaptor-related protein complex 1, beta 1 subunit
Background Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
Synonyms AP1B1; adaptor-related protein complex 1, beta 1 subunit; ADTB1, CLAPB2; AP-1 complex subunit beta-1; AP105A; BAM22; beta1-adaptin; beta-1-adaptin; beta-adaptin 1; beta-prime-adaptin; Golgi adaptor HA1/AP1 adaptin beta subunit; adaptor protein complex AP-
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AP1B1-1261H Recombinant Human AP1B1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human AP1B1-2318H Recombinant Human AP1B1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human AP1B1-644H Recombinant Human AP1B1 protein, GST-tagged Wheat Germ GST
    Human AP1B1-9707H Recombinant Human AP1B1, His-tagged E.coli His
    Mouse Ap1b1-618M Recombinant Mouse Ap1b1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat Ap1b1-3523R Recombinant Rat Ap1b1, His-tagged E.Coli or Yeast His
    Rat AP1B1-698R Recombinant Rat AP1B1 Protein Mammalian Cell His
    Zebrafish AP1B1-6919Z Recombinant Zebrafish AP1B1 Mammalian Cell His

    AP1B1 involved in several pathways and played different roles in them. We selected most pathways AP1B1 participated on our site, such as Adaptive Immune System, Clathrin derived vesicle budding, Disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System SPSB4; RAP1GAP2; EGF; AP2A1; UBE2L6; CTSH; GM11711; AF251705; TRIM9; KLRF1
    Clathrin derived vesicle budding PICALMB; CLINT1; PICALMA; CLTB; APPA; SNX9A; AP3S1; DTNBP1; HIP1RB; PLDN
    Disease ANTXR1; TRIM24; HDAC6; PDCD6IP; CCDC167; JAG2; KPNA5; CDK9; CFTR; SFTPC
    FOXA1 transcription factor network CC10; CEBPB; NRIP1; AP1B1; FOXA1; NR2F2; POU2F1; TFF1; NFIB; DSCAM
    Golgi Associated Vesicle Biogenesis NAPAA; AP1B1; TFR1B; AP1G1; PUM1; BLOC1S3; SH3D19; AP3S1; FTH1A; TPD52
    HIV Infection CDK9; PACS1; RCC1; PSIP1; DOCK2; VPS37A; CHMP4C; AP1B1; AP1G1; TCEB3
    Host Interactions of HIV factors PPIAL4A; AP1M2; RCC1; AP1B1; DOCK2; AP1S1; AP1G1; APOBEC3G; PACS1; PSIP1
    Immune System WIPF2; HUWE1; CD300LB; TRIM56; ACTR2B; OASL; KIF2B; CD200R2; SIGLEC8; EVL

    AP1B1 has several biochemical functions, for example, protein binding, protein kinase binding, protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1B1 itself. We selected most functions AP1B1 had, and list some proteins which have the same functions with AP1B1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CNPY2; B9D2; UBE2D3; VAMP3; ZFP423; STRAP; GNAI2; HIST2H4A; ABCF3; ISOC1
    protein kinase binding SKAP1; CHRNA7; LIMS1; SHC1; ADRA2A; SPAG16; CD36; LLGL1; MAP2K6; STX1B
    protein transporter activity AP3S2; IPO11; ZFYVE16; TNPO3; AP1S3A; IPO4; COX18; CALCRL; RAMP3; CALCR
    transporter activity SLC5A9; MUP17; CRABP2; SLC17A9; NUP88; AP1B1; SLC6A18; SLC2A11B; AQP3A; ATP5G1

    AP1B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1B1.

    Ap1g1; Ap1m1; nef; AP1S1; AP1S3; 1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate

    Saito, T; Ji, G; et al. Genetic variations in humans associated with differences in the course of hepatitis C. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 317:335-341(2004).

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