card9

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card9

Official Full Name caspase recruitment domain family, member 9
Background The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008]
Synonyms CARD9; caspase recruitment domain family, member 9; CANDF2; hCARD9; caspase recruitment domain-containing protein 9;
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CARD9-0399H Recombinant Human CARD9 Protein, GST-Tagged Wheat Germ GST
    Human CARD9-1475H Recombinant Human CARD9 protein, His & T7-tagged E.coli His/T7
    Human CARD9-2521H Recombinant Human CARD9 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CARD9-2668H Recombinant Human CARD9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CARD9-284HCL Recombinant Human CARD9 cell lysate N/A
    Human CARD9-3639H Recombinant Human CARD9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Card9-1476M Recombinant Mouse Card9 protein, His & T7-tagged E.coli His/T7
    Mouse Card9-1964M Recombinant Mouse Card9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse CARD9-2731M Recombinant Mouse CARD9 Protein Mammalian Cell His
    Rat CARD9-1137R Recombinant Rat CARD9 Protein Mammalian Cell His
    Zebrafish CARD9-6130Z Recombinant Zebrafish CARD9 Mammalian Cell His

    card9 involved in several pathways and played different roles in them. We selected most pathways card9 participated on our site, such as NOD-like receptor signaling pathway, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with card9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    NOD-like receptor signaling pathway HSP90B1; RELA; MAP3K7IP3; ERBB2IP; MAPK14B; LOC100033925; MAPK8B; CARD9; IL-8; NAIP1
    Tuberculosis CAP18; BAD; IFNA12; CD74; TRAF6; CORO1A; BCL2; MAPK12; FCGR2C; CALML3

    card9 has several biochemical functions, for example, CARD domain binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by card9 itself. We selected most functions card9 had, and list some proteins which have the same functions with card9. You can find most of the proteins on our site.

    Function Related Protein
    CARD domain binding RIPK2; CARD9; CARD11; MAVS; C9orf89; NOD1; CARD14
    protein binding CSRP2BP; CROP; ATG4A; BANF1; NUBP2; ACAD9; MZF1; GCG; DOCK1; KIF4A
    protein homodimerization activity SFTPC; PVRL1A; SLC39A13; PVALB; CCDC88A; GDNFA; BST2; SRR; GSTA4; PRPS1L1

    card9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with card9 here. Most of them are supplied by our site. Hope this information will be useful for your research of card9.

    TRIM42; ZNF572; MEOX2; a8k932_human; a8kad6_human; 386682

    Zhao, XQ; Zhu, LL; et al. C-type Lectin Receptor Dectin-3 Mediates Trehalose 6,6 '-Dimycolate (TDM)-induced Mincle Expression through CARD9/Bcl10/MALT1-dependent Nuclear Factor (NF)-kappa B Activation. JOURNAL OF BIOLOGICAL CHEMISTRY 289:30052-30062(2014).
    Desel, C; Werninghaus, K; et al. The Mincle-Activating Adjuvant TDB Induces MyD88-Dependent Th1 and Th17 Responses through IL-1R Signaling. PLOS ONE 8:-(2013).

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