• Official Full Name

    CD82 molecule

  • Overview

    This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms

    CD82; CD82 molecule; R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; CD82 antigen; tspan-27; C33 antigen; tetraspanin-27; inducible membrane protein R2; metastasis suppressor Kangai-1; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4));

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Fc
  • GST
  • His (Fc)
  • Avi
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD82-0867H Recombinant Human CD82 Protein, GST-Tagged Wheat Germ GST
Human CD82-27889TH Recombinant Human CD82 Wheat Germ N/A 267 amino acids
Human CD82-3969H Recombinant Human CD82 protein(Gly111-Leu228), His-tagged HEK293 C-His Gly111-Leu228
Human CD82-1960HCL Recombinant Human CD82 cell lysate Human Cell N/A
Human CD82-3970H Recombinant Human CD82(Gly103-Gln225) Protein, N-Fc-tagged HEK293 Fc
Human CD82-3070HF Recombinant Full Length Human CD82 Protein, GST-tagged In Vitro Cell Free System GST 267 amino acids
Human CD82-67HF Recombinant Full Length Human CD82 Protein In Vitro Cell Free System 267 amino acids
Human CD82-127H Recombinant Human CD82 protein, His-tagged E.coli His 35-264 aa
Human CD82-146H Recombinant Human CD82 Protein, C-His-tagged E.coli C-His
Human CD82-3721H Recombinant Human CD82 Protein (Gly111-Leu228), C-His tagged Mammalian cells C-His Gly111-Leu228
Mouse CD82-3111M Recombinant Mouse CD82 Protein Mammalian Cell His
Mouse CD82-1470M-B Recombinant Mouse CD82 Protein Pre-coupled Magnetic Beads HEK293
Mouse CD82-1470M Recombinant Mouse CD82 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cd82-2674M Recombinant Mouse Cd82 protein, His-SUMO-tagged E.coli His-SUMO 111-227aa
Homo sapiens (Human) RFL30269HF Recombinant Full Length Human Cd82 Antigen(Cd82) Protein, His-Tagged E.coli expression system His Full Length (1-267)
Mus musculus (Mouse) RFL2400MF Recombinant Full Length Mouse Cd82 Antigen(Cd82) Protein, His-Tagged E.coli expression system His Full Length (1-266)
Rattus norvegicus (Rat) RFL11281RF Recombinant Full Length Rat Cd82 Antigen(Cd82) Protein, His-Tagged E.coli expression system His Full Length (1-266)
Chicken CD82-1848C Recombinant Chicken CD82 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CD82 involved in several pathways and played different roles in them. We selected most pathways CD82 participated on our site, such as Direct p53 effectors, Integrated Pancreatic Cancer Pathway, p53 signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD82 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Direct p53 effectorsFDXR;ZNF385A;PLK3;BCL2L14;DUSP1;DDX5;DGCR8;CEBPZ;HIC1
Integrated Pancreatic Cancer PathwayTOP1;FST;IL11;FKBP1B;NOXA1;TFF1;RAPGEF3;RB1CC1;MYT1
p53 signaling pathwaySESN3;GADD45G;CD82

CD82 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD82 itself. We selected most functions CD82 had, and list some proteins which have the same functions with CD82. You can find most of the proteins on our site.

Function Related Protein

CD82 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD82 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD82.

VANGL1; CD19; NFKB1; NUP88; q9wmx2-pro_0000037550

Research Area

Related articles

Bawa, Z; Routledge, SJ; et al. Functional recombinant protein is present in the pre-induction phases of Pichia pastoris cultures when grown in bioreactors, but not shake-flasks. MICROBIAL CELL FACTORIES 13:-(2014).
Wang, Q; Wang, L; et al. L-22 enhances the invasiveness of endometrial stromal cells of adenomyosis in an autocrine manner. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:5762-5771(2014).
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        Q&As (7)

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        How do genetic variations in CD82 affect cancer progression? 02/19/2023

        Genetic mutations in CD82 can lead to reduced tumor-suppressive functions, enhancing the risk of cancer spread.

        What potential therapeutic applications arise from targeting CD82 in cancer treatment? 09/15/2022

        Targeting CD82 in cancer therapy could exploit its tumor-suppressive properties to prevent metastasis.

        How does CD82 interact with other membrane proteins in signaling pathways? 10/07/2020

        CD82 collaborates with other membrane proteins to regulate various signaling pathways, impacting cell behavior.

        What is the primary role of CD82 in cell signaling and communication? 11/09/2019

        CD82, a member of the tetraspanin family, is involved in modulating cell signaling and intercellular communication.

        What is the impact of altered CD82 activity on immune response? 11/24/2018

        Altered CD82 activity can influence immune cell interactions and responses.

        What role does CD82 play in tumor suppression and metastasis prevention? 06/22/2017

        CD82 acts as a tumor suppressor, inhibiting cancer cell migration and metastasis.

        How does CD82 contribute to the regulation of cell migration and adhesion? 06/12/2017

        It plays a crucial role in regulating cell migration and adhesion, key processes in tissue organization and wound healing.

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