Recombinant Human CD82 Protein, GST-Tagged

• Cat.No.: CD82-0867H
• Product Overview: Human CD82 full-length ORF (AAH00726, 1 a.a. - 267 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 55.11 kDa
• AA Sequence: MGSACIKVTKYFLFLFNLIFFILGA VILGFGVWILADKSSFISVLQTSSS SLRMGAYVFIGVGAVTMLMGFLGCI GAVNEVRCLLGLYFAFLLLILIAQV TAGALFYFNMGKLKQEMGGIVTELI RDYNSSREDSLQDAWDYVQAQVKCC GWVSFYNWTDNAELMNRPEVTYPCS CEVKGEEDNSLSVRKGFCEAPGNRT QSGNHPEDWPVYQEGCMEKVQAWLQ ENLGIILGVGVGVAIVELLGMVLSI CLCRHVHSEDYSKVPKY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CD82 CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal [ Homo sapiens ]
• Official Symbol: CD82
• Synonyms: CD82; CD82 antigen (R2 leukocyte antigen, antigen detected; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal; R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; CD82 antigen; C33 antigen; inducible membrane protein R2; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); metastasis suppressor Kangai-1; tetraspanin-27; tspan-27
• Gene ID: 3732
• mRNA Refseq: NM_001024844
• Protein Refseq: NP_001020015
• MIM: 600623
• UniProt ID: P27701