CXCL14

  • Official Full Name

    chemokine (C-X-C motif) ligand 14

  • Overview

    This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Jul 2008]
  • Synonyms

    CXCL14; chemokine (C-X-C motif) ligand 14; KEC; KS1; BMAC; BRAK; NJAC; MIP2G; MIP-2g; SCYB14; C-X-C motif chemokine 14; bolekine; MIP-2 gamma; chemokine BRAK; breast and kidney; tumor-suppressing chemokine; small-inducible cytokine B14; CXC chemokine in breast and kidney; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Biotin
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CXCL14-11720H Recombinant Human CXCL14, GST-tagged E.coli GST
Human CXCL14-90H Recombinant Human Chemokine (C-X-C Motif) Ligand 14 E.coli N/A
Human CXCL14-25H Recombinant Human CXCL14, His-tagged E.coli His
Human CXCL14-101H Human CXCL14, Biotin-tagged Biotin
Human CXCL14-7169HCL Recombinant Human CXCL14 293 Cell Lysate HEK293 N/A
Human CXCL14-2281H Recombinant Human CXCL14 Protein (Ser35-Glu111), N-GST tagged E.coli N-GST
Human CXCL14-014H Recombinant Human CXCL14 Protein, His-tagged Human Cells His
Human CXCL14-3398H Recombinant Human CXCL14 protein(Ser35-Glu111), Biotinylated E. coli N/A
Human CXCL14-2599H Recombinant Human CXCL14 protein, His-tagged E.coli His
Human CXCL14-23H Recombinant Human CXCL14 Protein, Biotin-tagged E.coli Biotin
Human CXCL14-2285HF Recombinant Full Length Human CXCL14 Protein, GST-tagged In Vitro Cell Free System GST
Mouse Cxcl14-7163M Recombinant Mouse Cxcl14 protein, His & T7-tagged E.coli His/T7
Mouse Cxcl14-614M Recombinant Mouse Cxcl14 protein E.coli N/A
Mouse Cxcl14-5252M Recombinant Mouse Cxcl14 protein, His-tagged E.coli His
Rat Cxcl14-1345R Recombinant Rat Cxcl14 protein E.coli N/A
Rhesus Macaque CXCL14-1109R Recombinant Rhesus monkey CXCL14 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CXCL14-934R Recombinant Rhesus Macaque CXCL14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CXCL14-934R-B Recombinant Rhesus Macaque CXCL14 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CXCL14-9165Z Recombinant Zebrafish CXCL14 Mammalian Cell His
Chicken CXCL14-6277C Recombinant Chicken CXCL14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CXCL14 Related Articles
  • CXCL14 Related Gene Family
  • CXCL14 Related Research Area

CXCL14 involved in several pathways and played different roles in them. We selected most pathways CXCL14 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCL14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL18RAP;IL15;LTBR;IL5;TNFRSF11A;TGFB2;IL13;PRL2;CXCR1
Chemokine signaling pathwayJAK3;STAT2;CCL15;STAT5B;GNG5;CRKL;CXCL9;SHC1;CXCL12

CXCL14 has several biochemical functions, for example, chemokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCL14 itself. We selected most functions CXCL14 had, and list some proteins which have the same functions with CXCL14. You can find most of the proteins on our site.

Function Related Protein
chemokine activityCCL4;CCL7;CCL27;CXCL19;CX3CL1;CXCL2;XCL1;CCL34A.4;CCL33.2
protein bindingMEIOB;DBNDD2;DDX58;PARD3;OFD1;CCL3;SYT11;KCP;MEIS1

CXCL14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCL14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCL14.

TRIM23; TEX11; CXCR4; REL; nadA; q81t38_bacan

Suzuki, H; Itoh, M; et al. CXCL14-like immunoreactivity in growth hormone-containing cells of urodele pituitaries. REGULATORY PEPTIDES 174:53-57(2012).
Lietz, R; Bayer, W; et al. Codelivery of the Chemokine CCL3 by an Adenovirus-Based Vaccine Improves Protection from Retrovirus Infection. JOURNAL OF VIROLOGY 86:1706-1716(2012).
  • Q&As
  • Reviews

Q&As (6)

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What is the relationship of CXCL14 protein to other genes or proteins? 09/14/2022

CXCL14 protein has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.

What is the specific role of CXCL14 protein in tumors? 02/18/2022

CXCL14 plays a dual role in tumors, on the one hand, it can inhibit the proliferation and metastasis of tumor cells, and on the other hand, it can promote the immune escape of tumor cells.

What are the types of mutations in CXCL14 protein? 05/03/2021

The types of mutations in CXCL14 protein include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

Could disease be treated by modulating CXCL14 protein levels? 09/12/2020

There are currently no drugs that directly regulate the levels of CXCL14 protein, but some diseases associated with CXCL14 protein can be treated by regulating its expression or inhibiting its activity.

How are mutations in CXCL14 protein detected and analyzed? 03/12/2020

Mutations in the CXCL14 protein can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

How to study the regulatory mechanism of CXCL14 protein? 12/23/2019

Studying the regulatory mechanism of CXCL14 protein requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Customer Reviews (3)

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Reviews
10/30/2022

    CXCL14 has important application value in the field of drug research and development, and has achieved certain research results.

    08/15/2022

      Good solubility, can be dissolved in a variety of buffers.

      03/06/2022

        I'm very satisfied. The quality is good and the price is affordable.

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