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Official Full Name chemokine (C-X-C motif) ligand 14
Background This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Jul 2008]
Synonyms CXCL14; chemokine (C-X-C motif) ligand 14; KEC; KS1; BMAC; BRAK; NJAC; MIP2G; MIP-2g; SCYB14; C-X-C motif chemokine 14; bolekine; MIP-2 gamma; chemokine BRAK; breast and kidney; tumor-suppressing chemokine; small-inducible cytokine B14; CXC chemokine in breast and kidney; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK);
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Human Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Biotin
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CXCL14-014H Recombinant Human CXCL14 Protein, His-tagged Human Cells His
    Human CXCL14-101H Human CXCL14, Biotin-tagged Biotin
    Human CXCL14-11720H Recombinant Human CXCL14, GST-tagged E.coli GST
    Human CXCL14-2163H Recombinant Human CXCL14 Protein, GST-tagged Wheat Germ GST
    Human CXCL14-25H Recombinant Human CXCL14, His-tagged E.coli His
    Human CXCL14-28059TH Recombinant Human CXCL14 E.coli N/A
    Human CXCL14-7169HCL Recombinant Human CXCL14 293 Cell Lysate HEK293 N/A
    Human CXCL14-90H Recombinant Human Chemokine (C-X-C Motif) Ligand 14 E.coli N/A
    Mouse Cxcl14-2393M Recombinant Mouse Cxcl14 Protein E. coli
    Mouse Cxcl14-388M Recombinant Mouse Chemokine (C-X-C motif) Ligand 14 E.coli N/A
    Mouse Cxcl14-614M Recombinant Mouse Cxcl14 protein E.coli N/A
    Mouse Cxcl14-7163M Recombinant Mouse Cxcl14 protein, His & T7-tagged E.coli His/T7
    Rat Cxcl14-1345R Recombinant Rat Cxcl14 protein E.coli N/A
    Rhesus Macaque CXCL14-1109R Recombinant Rhesus monkey CXCL14 Protein, His-tagged Mammalian Cell His
    Chicken CXCL14-6277C Recombinant Chicken CXCL14 Mammalian Cell His
    Zebrafish CXCL14-9165Z Recombinant Zebrafish CXCL14 Mammalian Cell His

    CXCL14 involved in several pathways and played different roles in them. We selected most pathways CXCL14 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCL14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IFNA21; KITLG; THPO; CCL23; CCL19B; GM2506; IFNW1; IFNA1; IL9R; CD40LG
    Chemokine signaling pathway CXCL16; GNB2; GNG11; Ccl21a; ARRB2; CXCL11; ROCK1; CCR1L1; ROCK2; GNG7

    CXCL14 has several biochemical functions, for example, chemokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCL14 itself. We selected most functions CXCL14 had, and list some proteins which have the same functions with CXCL14. You can find most of the proteins on our site.

    Function Related Protein
    chemokine activity CCL25; CCL34B.4; CCL39.1; IL8L2; XCL1; CCL27B; CXCL10; Ccl9; CCL19A.2; CCL25B
    protein binding AACS; KRT33B; TCTEX1D2; AGAP2; USP17L2; RELL2; MAGI2; LCE3E; DDX6; DRG1

    CXCL14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCL14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCL14.

    TRIM23; TEX11; CXCR4; REL; nadA; q81t38_bacan

    Suzuki, H; Itoh, M; et al. CXCL14-like immunoreactivity in growth hormone-containing cells of urodele pituitaries. REGULATORY PEPTIDES 174:53-57(2012).
    Lietz, R; Bayer, W; et al. Codelivery of the Chemokine CCL3 by an Adenovirus-Based Vaccine Improves Protection from Retrovirus Infection. JOURNAL OF VIROLOGY 86:1706-1716(2012).

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