|Official Full Name||chemokine (C-X-C motif) ligand 14|
|Background||This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Jul 2008]|
|Synonyms||CXCL14; chemokine (C-X-C motif) ligand 14; KEC; KS1; BMAC; BRAK; NJAC; MIP2G; MIP-2g; SCYB14; C-X-C motif chemokine 14; bolekine; MIP-2 gamma; chemokine BRAK; breast and kidney; tumor-suppressing chemokine; small-inducible cytokine B14; CXC chemokine in breast and kidney; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK);|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CXCL14 involved in several pathways and played different roles in them. We selected most pathways CXCL14 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCL14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||CCL3; TNFRSF25; IL9R; PDGFRA; CCL24; CCL4L2; Il6ra; IL13RA1; TNFRSF1B; CCL6|
|Chemokine signaling pathway||CCR5; LOC100033925; CXCR5; AKT2; CCL20; Ccl21c; GRK5; GNAI2; CCR7; HRAS|
CXCL14 has several biochemical functions, for example, chemokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCL14 itself. We selected most functions CXCL14 had, and list some proteins which have the same functions with CXCL14. You can find most of the proteins on our site.
|chemokine activity||CCL33.2; CCL3L1; CCL24; CCL6; CCL4; CXCL19; CCL1; CCL27; PF4; CCL34B.1|
|protein binding||AGR3; RXRA; KDRL; ZNF217; DDR2; STYK1; ENDOG; ARHGDIA; LIPE; UBE2U|
CXCL14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCL14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCL14.
TRIM23; TEX11; CXCR4; REL; nadA; q81t38_bacan