Recombinant Human CXCL14 293 Cell Lysate

Cat.No. : CXCL14-7169HCL
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Description : Antigen standard for chemokine (C-X-C motif) ligand 14 (CXCL14) is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
Source : HEK 293 cells
Species : Human
Components : This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Size : 0.1 mg
Storage Instruction : Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Applications : ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Tag : Non
Gene Name : CXCL14 chemokine (C-X-C motif) ligand 14 [ Homo sapiens ]
Official Symbol : CXCL14
Synonyms : CXCL14; chemokine (C-X-C motif) ligand 14; SCYB14, small inducible cytokine subfamily B (Cys X Cys), member 14 (BRAK); C-X-C motif chemokine 14; BMAC; bolekine; BRAK; breast and kidney; Kec; KS1; MIP 2g; NJAC; MIP-2 gamma; chemokine BRAK; tumor-suppressing chemokine; small-inducible cytokine B14; CXC chemokine in breast and kidney; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK); KEC; MIP2G; MIP-2g; SCYB14; MGC10687;
Gene ID : 9547
mRNA Refseq : NM_004887
Protein Refseq : NP_004878
MIM : 604186
UniProt ID : O95715
Chromosome Location : 5q31
Pathway : Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Senescence and Autophagy, organism-specific biosystem;
Function : chemokine activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
10/30/2022

    CXCL14 has important application value in the field of drug research and development, and has achieved certain research results.

    08/15/2022

      Good solubility, can be dissolved in a variety of buffers.

      03/06/2022

        I'm very satisfied. The quality is good and the price is affordable.

        Q&As (6)

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        What is the relationship of CXCL14 protein to other genes or proteins? 09/14/2022

        CXCL14 protein has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.

        What is the specific role of CXCL14 protein in tumors? 02/18/2022

        CXCL14 plays a dual role in tumors, on the one hand, it can inhibit the proliferation and metastasis of tumor cells, and on the other hand, it can promote the immune escape of tumor cells.

        What are the types of mutations in CXCL14 protein? 05/03/2021

        The types of mutations in CXCL14 protein include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

        Could disease be treated by modulating CXCL14 protein levels? 09/12/2020

        There are currently no drugs that directly regulate the levels of CXCL14 protein, but some diseases associated with CXCL14 protein can be treated by regulating its expression or inhibiting its activity.

        How are mutations in CXCL14 protein detected and analyzed? 03/12/2020

        Mutations in the CXCL14 protein can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

        How to study the regulatory mechanism of CXCL14 protein? 12/23/2019

        Studying the regulatory mechanism of CXCL14 protein requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

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