Recombinant Human IGFBP4 protein
Cat.No. : | IGFBP4-755H |
Product Overview : | Recombinant Human IGFBP4 (Glu99-Lys327) protein carried no tag and was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
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Description : | Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3). |
Source : | HEK293 |
Species : | Human |
Predicted N Terminal : | Glu99 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 25.8 kDa. As a result of glycosylation, the protein migrates as 30-32 kDa under reducing (R) condition, and 28-30 kDa and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE). |
Protein length : | Glu99-Lys327 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IGFBP4 |
Official Symbol : | IGFBP4 |
Synonyms : | IGFBP4; insulin-like growth factor binding protein 4; insulin like growth factor binding protein 4; insulin-like growth factor-binding protein 4; BP 4; HT29 IGFBP; IBP4; IGF binding protein 4; IGFBP 4; IBP-4; IGF-binding protein 4; BP-4; IGFBP-4; HT29-IGFBP |
Gene ID : | 3487 |
mRNA Refseq : | NM_001552 |
Protein Refseq : | NP_001543 |
MIM : | 146733 |
UniProt ID : | P22692 |
Products Types
◆ Recombinant Protein | ||
Igfbp4-1228M | Recombinant Mouse Igfbp4 Protein, MYC/DDK-tagged | +Inquiry |
IGFBP4-302H | Recombinant Human IGFBP4 Protein, His-tagged | +Inquiry |
IGFBP4-8819C | Active Recombinant Cynomolgus IGFBP4 protein(Met1-Glu258), His-tagged | +Inquiry |
IGFBP4-1385H | Recombinant Human IGFBP4 Protein | +Inquiry |
IGFBP4-4429H | Recombinant Human IGFBP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IGFBP4-1231CCL | Recombinant Cynomolgus IGFBP4 cell lysate | +Inquiry |
IGFBP4-2925MCL | Recombinant Mouse IGFBP4 cell lysate | +Inquiry |
IGFBP4-2926HCL | Recombinant Human IGFBP4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIGFBP4 plays a key role in bone development, regulating bone-forming and bone-resorbing cells.
IGFBP4 impacts cardiovascular health, influencing atherosclerosis and heart disease processes.
Dysregulation of IGFBP4 is linked to aging and the progression of age-related diseases.
IGFBP4 is involved in metabolic regulation, affecting insulin sensitivity and glucose metabolism.
IGFBP4 modulates IGF activity, affecting growth and metabolic functions in tissues.
Changes in IGFBP4 expression influence wound healing and tissue repair mechanisms.
IGFBP4 influences cancer progression, particularly in cancers sensitive to hormonal changes.
Customer Reviews (3)
Write a reviewAccurate protein structural analysis, crucial for our investigations.
Exceptional protein expression optimization support, greatly appreciated.
Reliable mass spectrometry analysis, pivotal for proteomics studies.
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