Recombinant Human IGFBP4 protein, His-tagged
Cat.No. : | IGFBP4-205H |
Product Overview : | Recombinant Human IGFBP4 (Asp22-Glu258) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Insulin-like growth factor-binding protein 4 (IGFBP-4) is also known as IGF-binding protein 4, which contains an IGFBP domain and a thyroglobulin type-I domain. IGFBP-4 binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBP-4 is a unique protein and it consistently inhibits several cancer cells in vivo and in vitro. Its inhibitory action has been shown in vivo in prostate and colon. IGFBP-4 is secreted by all colon cancer cells. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Asp22 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 27.9 kDa. The protein migrates as 33-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Asp22-Glu258 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IGFBP4 |
Official Symbol : | IGFBP4 |
Synonyms : | IGFBP4; insulin-like growth factor binding protein 4; insulin like growth factor binding protein 4; insulin-like growth factor-binding protein 4; BP 4; HT29 IGFBP; IBP4; IGF binding protein 4; IGFBP 4; IBP-4; IGF-binding protein 4; BP-4; IGFBP-4; HT29-IGFBP |
Gene ID : | 3487 |
mRNA Refseq : | NM_001552 |
Protein Refseq : | NP_001543 |
MIM : | 146733 |
UniProt ID : | P22692 |
Products Types
◆ Recombinant Protein | ||
IGFBP4-2040R | Recombinant Rhesus Macaque IGFBP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP4-302H | Recombinant Human IGFBP4 Protein, His-tagged | +Inquiry |
IGFBP4-1385H | Recombinant Human IGFBP4 Protein | +Inquiry |
Igfbp4-1228M | Recombinant Mouse Igfbp4 Protein, MYC/DDK-tagged | +Inquiry |
IGFBP4-1389H | Recombinant Human IGFBP4 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
IGFBP4-1231CCL | Recombinant Cynomolgus IGFBP4 cell lysate | +Inquiry |
IGFBP4-2926HCL | Recombinant Human IGFBP4 cell lysate | +Inquiry |
IGFBP4-2925MCL | Recombinant Mouse IGFBP4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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