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Recombinant Human IGFBP4 Protein

Cat.No. : IGFBP4-1385H
Product Overview : Recombinant human IGFBP4 protein, was expressed in Hi-5 Insect cells.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008].
Source : Insect cells
Species : Human
Form : Lyophilized from a 0.2 µM filtered solution of 20 mM phosphate buffer, 100 mM NaCl, pH 7.2
Molecular Mass : 25.8 kDa
Purity : Resuspend the protein in the desired concentration in proper buffer
Concentration : Resuspend the protein in the desired concentration in proper buffer
Gene Name : IGFBP4 insulin-like growth factor binding protein 4 [ Homo sapiens ]
Official Symbol : IGFBP4
Synonyms : BP-4; HT29-IGFBP; IBP4; IGFBP-4
Gene ID : 3487
mRNA Refseq : NM_001552
Protein Refseq : NP_001543
MIM : 146733
UniProt ID : P22692

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What role does IGFBP4 play in bone growth and development, particularly in regulating osteoblast and osteoclast activity? 09/09/2022

IGFBP4 plays a key role in bone development, regulating bone-forming and bone-resorbing cells.

What is the impact of IGFBP4 on cardiovascular health, particularly in atherosclerosis and heart disease? 04/30/2022

IGFBP4 impacts cardiovascular health, influencing atherosclerosis and heart disease processes.

What are the effects of IGFBP4 dysregulation on aging and age-related diseases? 10/08/2019

Dysregulation of IGFBP4 is linked to aging and the progression of age-related diseases.

How does IGFBP4 contribute to metabolic regulation and insulin sensitivity? 11/25/2018

IGFBP4 is involved in metabolic regulation, affecting insulin sensitivity and glucose metabolism.

How does IGFBP4 modulate the activity of insulin-like growth factors (IGFs) in various tissues? 10/23/2018

IGFBP4 modulates IGF activity, affecting growth and metabolic functions in tissues.

How do alterations in IGFBP4 expression or function affect wound healing and tissue repair? 07/09/2018

Changes in IGFBP4 expression influence wound healing and tissue repair mechanisms.

How does IGFBP4 influence cancer progression, especially in hormone-dependent cancers? 05/26/2018

IGFBP4 influences cancer progression, particularly in cancers sensitive to hormonal changes.

Customer Reviews (3)

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Reviews
02/25/2019

    Accurate protein structural analysis, crucial for our investigations.

    10/23/2018

      Exceptional protein expression optimization support, greatly appreciated.

      06/06/2018

        Reliable mass spectrometry analysis, pivotal for proteomics studies.

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