IL26
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Official Full Name
interleukin 26
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Overview
Interleukin 26 (IL-26) is a homodimer cytokine belonging to the IL-10 family that is expressed in certain herpesvirus-transformed T cells but IL-26 induces rapid phosphorylation of the transcription factors STAT1 and STAT3,Which enhance IL-10 and IL-8 secretion and as expression of the CD54 molecule on the surface of epithelial cells. IL-26's function in human disease is unknown, however research has found that IL-26 expression is up-regulated in active Crohn's disease, and therefore may play an active role along with Th17 cells in various autoimmune diseases. -
Synonyms
IL26; interleukin 26; interleukin-26; AK155; IL 26; IL-26;
- Cell & Tissue Lysates
- Recombinant Proteins
- Human
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- Yeast
- GST
- His
- B2M
- Trx
- N
- MBP
- C
- Avi
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
IL26 involved in several pathways and played different roles in them. We selected most pathways IL26 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL26 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | CXCL10;IFNPHI3;TNFRSF1B;Il4ra;IFNGR2;GM13304;ACVR2A;TNFSF8;IL18RAP |
IL26 has several biochemical functions, for example, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL26 itself. We selected most functions IL26 had, and list some proteins which have the same functions with IL26. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | IL4;AREG;WNT1;GM13289;RNF207B;CXCL9;IFNA17;GDF10B;BMP6 |
IL26 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL26 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL26.
Research Area
Related articles
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewThe background is clean and non-immunogenic.
Expression is very high and can be easily detected.
Yield is very high and can meet a lot of my needs.
Q&As (6)
Ask a questionThe level of Il26 in vivo can be detected by enzyme-linked immunosorbent assay and flow cytometry.
Il26 can mediate the inflammatory response, regulating it by attracting immune cells and enhancing inflammation.
Il26 can be used for laboratory animal studies.
It can mediate cell growth and differentiation through JAK-STAT signal transduction pathway.
The production process of Il26 can be optimized by optimizing the transformation system, improving the culture conditions and optimizing the purification process.
Drugs targeting Il26 can be designed through computer simulation, drug screening and molecular modification.
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