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Active Recombinant Human IL26 Protein (Lys22-Gln171), C-His tagged, Animal-free, Carrier-free

Cat.No. : IL26-252H
Product Overview : Recombinant Human IL26 Protein (Lys22-Gln171) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.
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Description : Interleukin 26 (IL-26) predicts a molecular mass of 19.8 kDa, is expressed in certain herpesvirus-transformed T cells but not in primary stimulated T cells. T helper 1 cells and Th17 memory CD4+ cells are the major sources of IL-26. More accurately, IL-26 is expressed by pro-inflammatory IL-17 producing T cells in chronically inflamed tissues.
Source : E. coli
Species : Human
Tag : His
Form : Lyophilized
Bio-activity : Measure by its ability to induce IL-10 secretion in COLO205 cells. The ED50 for this effect is < 150 ng/mL.
Molecular Mass : The protein has a calculated MW of 18.53 kDa.
The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis).
Protein length : Lys22-Gln171
Endotoxin : < 0.1 EU/μg of the protein by the LAL method.
Purity : >98% as determined by SDS-PAGE analysis.
Storage : This product is stable after storage at:
-20 centigrade for 12 months in lyophilized state from date of receipt.
-20 or -80 centigrade for 2 weeks under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping : The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.
Gene Name : IL26 interleukin 26 [ Homo sapiens (human) ]
Official Symbol : IL26
Synonyms : IL26; interleukin 26; interleukin-26; AK155; IL 26; IL-26;
Gene ID : 55801
mRNA Refseq : NM_018402
Protein Refseq : NP_060872
MIM : 605679
UniProt ID : Q9NPH9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
12/11/2022

    The background is clean and non-immunogenic.

    06/03/2021

      Expression is very high and can be easily detected.

      07/04/2020

        Yield is very high and can meet a lot of my needs.

        Q&As (6)

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        How to detect the level of Il26 in vivo? 06/11/2022

        The level of Il26 in vivo can be detected by enzyme-linked immunosorbent assay and flow cytometry.

        What is the role of Il26 in inflammatory response? 06/03/2022

        Il26 can mediate the inflammatory response, regulating it by attracting immune cells and enhancing inflammation.

        Can recombinant Il26 be used in laboratory animals? 01/14/2022

        Il26 can be used for laboratory animal studies.

        What is the role of Il26 in cell signal transduction pathway? 11/30/2020

        It can mediate cell growth and differentiation through JAK-STAT signal transduction pathway.

        How to optimize the production process of Il26? 06/26/2020

        The production process of Il26 can be optimized by optimizing the transformation system, improving the culture conditions and optimizing the purification process.

        How to design drugs that target Il26? 11/21/2019

        Drugs targeting Il26 can be designed through computer simulation, drug screening and molecular modification.

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