Recombinant Active Human IL26 Protein, His-tagged(C-ter)

• Cat.No.: IL26-184H
• Product Overview: Recombinant Active Human IL26 Protein with His tag (C-ter) was expressed in E. coli.

Specification

• Description: This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq, Jul 2008]
• Source: E. coli
• Species: Human
• Tag: His
• Form: Powder
• Bio-activity: Determined by its ability to induce IL-10 secretion in COLO205 cells. The ED50 for this effect is < 150 ng/mL.
• AA Sequence: MKHKQSSFTKSCYPRGTLSQAVDAL YIKAAWHKATIPEDRIKNIRLLKKK TKKQFMKNCQFQEQLLSFFMEDVFG QLQLQGCKKIRFVEDFHSLRQKLSH CISCASSAREMKSITRMKRIFYRIG NKGIYKAISELDILLSWIKKLLESS Q
• Endotoxin: Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
• Purity: > 98% (by SDS-PAGE)
• Applications: SDS-PAGE
• Notes: For laboratory research only, not for drug, diagnostic or other use.
• Storage: Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
• Storage Buffer: PBS (pH 8.0)
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.

Gene Information

• Gene Name: IL26 interleukin 26 [ Homo sapiens ]
• Official Symbol: IL26
• Synonyms: IL26; interleukin 26; interleukin-26; AK155; IL 26; IL-26
• Gene ID: 55801
• mRNA Refseq: NM_018402
• Protein Refseq: NP_060872
• MIM: 605679
• UniProt ID: Q9NPH9

Reviews

12/11/2022

The background is clean and non-immunogenic.

06/03/2021

Expression is very high and can be easily detected.

07/04/2020

Yield is very high and can meet a lot of my needs.

Q&As

How to detect the level of Il26 in vivo?

The level of Il26 in vivo can be detected by enzyme-linked immunosorbent assay and flow cytometry.

What is the role of Il26 in inflammatory response?

Il26 can mediate the inflammatory response, regulating it by attracting immune cells and enhancing inflammation.

Can recombinant Il26 be used in laboratory animals?

Il26 can be used for laboratory animal studies.

What is the role of Il26 in cell signal transduction pathway?

It can mediate cell growth and differentiation through JAK-STAT signal transduction pathway.

How to optimize the production process of Il26?

The production process of Il26 can be optimized by optimizing the transformation system, improving the culture conditions and optimizing the purification process.

How to design drugs that target Il26?

Drugs targeting Il26 can be designed through computer simulation, drug screening and molecular modification.