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Recombinant Human IL26 Protein (22-171 aa), His-B2M-tagged

Cat.No. : IL26-2446H
Product Overview : Recombinant Human IL26 Protein (22-171 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-B2M tag at the N-terminal. Protein Description: Full Length of Mature Protein.
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  • Gene Information
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Description : May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Source : E. coli
Species : Human
Tag : His-B2M
Form : Tris-based buffer,50% glycerol
Molecular Mass : 31.6 kDa
Protein length : 22-171 aa
AA Sequence : KHKQSSFTKSCYPRGTLSQAVDALY IKAAWLKATIPEDRIKNIRLLKKKT KKQFMKNCQFQEQLLSFFMEDVFGQ LQLQGCKKIRFVEDFHSLRQKLSHC ISCASSAREMKSITRMKRIFYRIGN KGIYKAISELDILLSWIKKLLESSQ
Purity : > 85% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Gene Name : IL26 interleukin 26 [ Homo sapiens ]
Official Symbol : IL26
Synonyms : IL26; interleukin 26; interleukin-26; AK155; IL 26; IL-26;
Gene ID : 55801
mRNA Refseq : NM_018402
Protein Refseq : NP_060872
MIM : 605679
UniProt ID : Q9NPH9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How to detect the level of Il26 in vivo? 06/11/2022

The level of Il26 in vivo can be detected by enzyme-linked immunosorbent assay and flow cytometry.

What is the role of Il26 in inflammatory response? 06/03/2022

Il26 can mediate the inflammatory response, regulating it by attracting immune cells and enhancing inflammation.

Can recombinant Il26 be used in laboratory animals? 01/14/2022

Il26 can be used for laboratory animal studies.

What is the role of Il26 in cell signal transduction pathway? 11/30/2020

It can mediate cell growth and differentiation through JAK-STAT signal transduction pathway.

How to optimize the production process of Il26? 06/26/2020

The production process of Il26 can be optimized by optimizing the transformation system, improving the culture conditions and optimizing the purification process.

How to design drugs that target Il26? 11/21/2019

Drugs targeting Il26 can be designed through computer simulation, drug screening and molecular modification.

Customer Reviews (3)

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Reviews
12/11/2022

    The background is clean and non-immunogenic.

    06/03/2021

      Expression is very high and can be easily detected.

      07/04/2020

        Yield is very high and can meet a lot of my needs.

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