Recombinant Human IL26 Protein (22-171 aa), His-B2M-tagged IL26-2446H

Recombinant Human IL26 Protein (22-171 aa), His-B2M-tagged

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Recombinant Human IL26 Protein (22-171 aa), His-B2M-tagged

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Cat.No. : IL26-2446H
Product Overview : Recombinant Human IL26 Protein (22-171 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-B2M tag at the N-terminal. Protein Description: Full Length of Mature Protein.
Description : May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Source : E. coli
Species : Human
Tag : His-B2M
Form : Tris-based buffer,50% glycerol
Molecular Mass : 31.6 kDa
Protein length : 22-171 aa
AA Sequence : KHKQSSFTKSCYPRG TLSQAVDALYIKAAW LKATIPEDRIKNIRL LKKKTKKQFMKNCQF QEQLLSFFMEDVFGQ LQLQGCKKIRFVEDF HSLRQKLSHCISCAS SAREMKSITRMKRIF YRIGNKGIYKAISEL DILLSWIKKLLESSQ
Purity : > 85% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : IL26 interleukin 26 [ Homo sapiens ]
Official Symbol : IL26
Synonyms : IL26; interleukin 26; interleukin-26; AK155; IL 26; IL-26;
Gene ID : 55801
mRNA Refseq : NM_018402
Protein Refseq : NP_060872
MIM : 605679
UniProt ID : Q9NPH9

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