| Cat.No. : |
IL26-2446H |
| Product Overview : |
Recombinant Human IL26 Protein (22-171 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-B2M tag at the N-terminal. Protein Description: Full Length of Mature Protein. |
| Description : |
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His-B2M |
| Form : |
Tris-based buffer,50% glycerol |
| Molecular Mass : |
31.6 kDa |
| Protein length : |
22-171 aa |
| AA Sequence : |
KHKQSSFTKS CYPRGTLSQA VDALYIKAAW LKATIPEDRI KNIRLLKKKT KKQFMKNCQF QEQLLSFFME DVFGQLQLQG CKKIRFVEDF HSLRQKLSHC ISCASSAREM KSITRMKRIF YRIGNKGIYK AISELDILLS WIKKLLESSQ |
| Purity : |
> 85% as determined by SDS-PAGE. |
| Notes : |
Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : |
A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
| Figure : |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.