MAPK13 Protein


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Official Full Name mitogen-activated protein kinase 13
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Synonyms MAPK13; mitogen-activated protein kinase 13; PRKM13; p38delta; SAPK4; MAPK 13; MAP kinase 13; MAP kinase p38 delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; MGC99536
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Insect Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • His-SUMO
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK13-1285H Recombinant Human Mitogen-Activated Protein Kinase 13, His-tagged Human His
    Human MAPK13-31379TH Recombinant Human MAPK13, His-tagged E.coli His
    Human MAPK13-31380TH Recombinant Human MAPK13 N/A
    Human MAPK13-31H Recombinant human biotinylated MAPK13, His-tagged E.coli His
    Human MAPK13-357H Recombinant Human MAPK13 Protein, GST-tagged, Activated Insect Cell GST
    Human MAPK13-374H Recombinant Human MAPK13, GST-tagged, Active Sf9 Insect Cell GST
    Human MAPK13-48H Recombinant Human MAPK13, GST-tagged Sf9 Insect Cell GST
    Human MAPK13-737H Recombinant Human Mitogen-activated Protein Kinase 13 E.coli N/A
    Human MAPK13-945H Recombinant Human MAPK13, GST tagged Insect Cell GST
    Human MAPK13-574HCL Recombinant Human MAPK13 cell lysate Insect Cell N/A
    Human MAPK13-1297HF Recombinant Full Length Human MAPK13 Protein, GST-tagged E.coli GST
    Human MAPK13-3205H Recombinant Human MAPK13 protein, His-SUMO-tagged E.coli His-SUMO
    Human MAPK13-2436H Recombinant Human MAPK13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MAPK13-383H Recombinant Human MAPK13 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Mapk13-3940M Recombinant Mouse Mapk13 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    MAPK13 involved in several pathways and played different roles in them. We selected most pathways MAPK13 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway CDC25B; CDC42L2; GADD45G; PRKACBA; MAP2K4B; RPS6KA4; RELA; GRB2; MKNK2A; HSP70L
    Rap signaling pathway SIPA1L1; FGF7; FGF19; LAT; CDH1; PDGFRA; Adcy4; PIK3R1; FGF6; FGF9
    FoxO signaling pathway HOMER1; GADD45BB; CAT; MAPK11; ARAF; RAF1B; USP7; FOXG1; FOXO6; PRKAA2
    Sphingolipid signaling pathway LASS4; PPP2R1B; MAP3K5; GNAI2; PPP2R5E; PPP2CA; ASAH1; MAP2K1; TRP53; KRAS
    Adrenergic signaling in cardiomyocytes CALM1B; SCN4BA; CACNB3; CALM1; SLC9A1; CACNG6A; PLN; ADCY1B; Adcy4; ADCY8
    Osteoclast differentiation LILRB1; TRAF2; NFATC1; CAMK4; RAC1; CALCR; FCGR2A; PIK3CD; MAPK9; SQSTM1
    Signaling pathways regulating pluripotency of stem cells DLX5; WNT11; INHBB; ID2; MEIS1; APC; PCGF1; WNT10B; FZD3; HESX1
    Platelet activation GP1BB; MYLK; VAMP8; TBXAS1; PLCB1; PIK3CA; GNAI2; F2R; ARHGEF1; GNAI3
    Toll-like receptor signaling pathway TICAM2; MAP2K2B; RELA; IFNA16; CXCL10; MAPK1; IL12A; IKBKE; STAT1B; PIK3CA
    NOD-like receptor signaling pathway MAPK3; TRIP6; MAPK12B; MAPK14A; HSP90AA1.1; CARD18; NFKBIAA; MAPK1; HSP90AA1; CARD9
    RIG-I-like receptor signaling pathway IFNK; MAPK12A; NLRX1; IFNA4; ISG15; MAPK14B; ATG12; IFIH1; MAPK12; OTUD5
    T cell receptor signaling pathway MAP3K7; NFKBIB; MAP2K2; MAPK3; PAK7; NFKBIE; MAP3K14; PIK3CG; OXSR1A; NFATC3
    Fc epsilon RI signaling pathway RAC3; NRAS; RAF1; PIK3CB; SYK; GAB2; PIK3R5; FCER1G; BTK; PIK3R3
    TNF signaling pathway CXCL10; PIK3R2; IL6; MMP9; MAPK11; MAP3K14; AKT1; ITCH; Casp3; CREB3L3
    Leukocyte transendothelial migration CLDN23; NIPAL1; VAV3; CLDN8; PIK3CD; CLDN16; CLDN5; CLDN1; CLDN11; RAC1
    Neurotrophin signaling pathway MAP2K1; NTRK2; TP53; CAMK2B; NGF; MAP3K5; CDC42; BCL2; PIK3CG; MAPK13
    Retrograde endocannabinoid signaling GRM5; GABRA3; MAPK12; ABHD6; PRKCA; GNG5; GNG13; GRIA2; MAPK11; GNG11
    Dopaminergic synapse GSK3A; KCNJ9; GNG13; KIF5A; DRD1; DRD4; GNAI3; CREB3L2; ARNTL; GNAI1
    Inflammatory mediator regulation of TRP channels CYP4A14; ASIC5; PRKCG; IL1RAP; CALML5; PPP1CC; MAPK11; ASIC3; CAMK2A; P2RY2
    GnRH signaling pathway GRB2A; MAP2K4; MAPK11; MAPK10; PLA2G4C; PLD1; MAP2K2; MAPK3; CDC42L; MAPK8
    Progesterone-mediated oocyte maturation PIK3CB; SPDYA; CDC25A; MAPK14A; FZR1A; CPEB3; RPS6KAL; FZR1; SPDYB; MAPK13
    Prolactin signaling pathway CCND1; SOCS6; SOCS2; PIK3CD; NRAS; ESR2; MAPK13; PRP2; FOXO3; RELA
    Amyotrophic lateral sclerosis (ALS) MAP2K3; NEFL; DERL1; CASP12; BAD; MAP3K5; APAF1; CCS; BID; GRIN2C
    Epithelial cell signaling in Helicobacter pylori infection ATP6V1F; ATP6V0A4; MAPK13; JAM2; CXCR1; PAK1; ATP6V1G3; MAPK10; ATP6V0B; GIT1
    Shigellosis SRC; DIAPH1; MAPK10; MAPK9; IL-8; MAPK8; ROCK2; ITGA5; WASF1; WASL
    Salmonella infection TLR4BA; NOS2; RHOGD; MAPK13; WAS; RILP; ARPC5L; DYNC2H1; PKN2; CCL4L1
    Pertussis MAPK13; CALML3; CASP7; CD14; CALM3; IL6; IRF8; GNAI2; Hc; IL23
    Leishmaniasis Itgam&Itgb2; NCF1; FCGR3A; FCGR2C; TGFB2; H2-AA; RELA; MARCKSL1; MAPK11; ITGAM
    Chagas disease (American trypanosomiasis) PLCB2; CALR; NFKB1; CCL2; PPP2R2C; TGFB3; TNF; Fasl; PPP2CA; BDKRB2
    Toxoplasmosis CASP8; MAPK11; HLA-DQA2; PIK3CB; STAT3; IKBKB; MAPK1; RELA; PIK3CG; PIK3R3
    Tuberculosis HLA-DPB1; IL10RA; IFNG; IFNA16; AKT1; CASP8; MAPK3; BCL10; BAX; HLA-DMA
    Hepatitis C CLDN16; OAS1B; EIF2AK3; IFNAR2; OAS2; PIK3R1; MAPK13; CLDN22; BAD; CLDN7
    Influenza A IRF3; CASP1; IL18; STAT1; MAVS; IFNA16; FAS; Ccl12; BMA2; PIK3R5
    Epstein-Barr virus infection POLR3E; MAPK9; HSPA1B; POLR2G; PSMD7; MDM2; YWHAB; IL10RB; TRAF5; NUP214
    Proteoglycans in cancer WNT3A; MSN; VTN; SMAD2; WNT7A; PAK1; CAMK2A; SDC1; TLR4; ITPR3

    MAPK13 has several biochemical functions, for example, ATP binding, MAP kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK13 itself. We selected most functions MAPK13 had, and list some proteins which have the same functions with MAPK13. You can find most of the proteins on our site.

    Function Related Protein
    MAP kinase activity NLK2; MAPK13; MAPK11; MAPK8B; MAPK3; MAPK12A; MAPK12; MAPK7; MAPK12B; MAPK14A
    protein binding OSTA; SSNA1; FAM131C; NUDT18; ARL4C; DEPDC6; DDX18; FAM192A; ATP6V1C1; DRD1A
    protein serine/threonine kinase activity SBK1; TRIOA; CSNK1G2; MAPK1; Aatk; SLC14A2; PRKCHA; AKT3; TSSK3; ZNF143B

    MAPK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK13.

    PRKD1; FPR1; saicar; PKM; ATF2; MAPKAPK3; Pkd1; MAP3K4; GPX4; SMAD4; ANKLE2; AKIP1; pi3p

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