MAPK13 Protein


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Official Full Name mitogen-activated protein kinase 13
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Synonyms MAPK13; mitogen-activated protein kinase 13; PRKM13; p38delta; SAPK4; MAPK 13; MAP kinase 13; MAP kinase p38 delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; MGC99536
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Insect Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • His-SUMO
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK13-357H Active Recombinant Human MAPK13 Protein, GST-tagged, Activated Insect Cell GST Inquiry
    Human MAPK13-1285H Recombinant Human Mitogen-Activated Protein Kinase 13, His-tagged Human His Inquiry
    Human MAPK13-31379TH Recombinant Human MAPK13, His-tagged E.coli His Inquiry
    Human MAPK13-31380TH Recombinant Human MAPK13 N/A Inquiry
    Human MAPK13-31H Recombinant human biotinylated MAPK13, His-tagged E.coli His Inquiry
    Human MAPK13-374H Recombinant Human MAPK13, GST-tagged, Active Sf9 Insect Cell GST Inquiry
    Human MAPK13-48H Recombinant Human MAPK13, GST-tagged Sf9 Insect Cell GST Inquiry
    Human MAPK13-737H Recombinant Human Mitogen-activated Protein Kinase 13 E.coli N/A Inquiry
    Human MAPK13-945H Recombinant Human MAPK13, GST tagged Insect Cell GST Inquiry
    Human MAPK13-574HCL Recombinant Human MAPK13 cell lysate Insect Cell N/A Inquiry
    Human MAPK13-1297HF Recombinant Full Length Human MAPK13 Protein, GST-tagged E.coli GST Inquiry
    Human MAPK13-3205H Recombinant Human MAPK13 protein, His-SUMO-tagged E.coli His-SUMO Inquiry
    Human MAPK13-2436H Recombinant Human MAPK13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human MAPK13-383H Recombinant Human MAPK13 Protein, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Mouse Mapk13-3940M Recombinant Mouse Mapk13 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry

    MAPK13 involved in several pathways and played different roles in them. We selected most pathways MAPK13 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rap signaling pathway PFN3; LPAR3; FGF4; MAGI1; PRKD3; RAF1; MAPK13; RAPGEF6; GRIN1; ITGB2L
    FoxO signaling pathway GRB2B; SIRT1; FBXO25; IGF1RB; CCND2A; EGFRA; PRMT1; MAPK14A; SGK2A; PCK2
    Sphingolipid signaling pathway PIK3R2; SPHK2; PPP2R1B; PRKCE; TNF; PPP2R5C; RAC2; BDKRB2; CERS4; SPTLC3
    Adrenergic signaling in cardiomyocytes MAPK14A; PPP2R2C; FXYD2; PPP2R5B; VMHC; PPP2R1B; ATP2B1; CACNB4A; PRKACBA; CACNG2A
    VEGF signaling pathway PTK2AA; PXN; NRAS; PRKCBA; PLA2G4A; CDC42L; SHC2; MAP2K2A; PPP3R2; PTGS2B
    Osteoclast differentiation MITF; LILRB1; NOX3; AKT2; PIK3R3; TGFB1; FCGR2A; SIRPA; LILRA2; RAC1
    Signaling pathways regulating pluripotency of stem cells PIK3R3; HESX1; MAPK12; WNT6; SMARCAD1; WNT2; APC; DLX5; PIK3CG; WNT9A
    Platelet activation GNAI2; PLCB4; PLCG2; PIK3R3; GUCY1A3; MAPK13; PIK3CD; PRKG1; ROCK2; VAMP8
    Toll-like receptor signaling pathway IFNPHI3; TLR3; MAP2K4; SPP1; CASP8; IFNA16; TLR8; TRAF3; RAC1A; MAPK10
    NOD-like receptor signaling pathway RIPK2; HSP90AA1.2; TNFAIP3; CXCL8B.3; RELA; IL8L1; TAB2; IL1B; TRAF6; NLRP1
    RIG-I-like receptor signaling pathway Ifna11; MAP3K7; MAPK9; IFNA8; IL12B; IFNPHI1; NFKBIAA; IFNA2; RNF207B; IFIH1
    T cell receptor signaling pathway VAV2; SHB; CD3G; PPP3R1; NCK1; CD8A; TEC; PAK2; PDPK1; MAP2K7
    Fc epsilon RI signaling pathway KRAS; BTK; RAC3; PLCG1; SOS1; GAB2; INPP5D; MAP2K2; TNF; GM-CSF
    TNF signaling pathway TRAF3; MAPK9; MAP2K6; TRAF2; IL6; BAG4; CXCL5; PIK3R2; MAP2K7; IKBKG
    Leukocyte transendothelial migration CYBB; EZR; ACTN4; TXK; ACTN3; PLCG2; CLDN23; MYL10; JAM3; PIK3CG
    Neurotrophin signaling pathway CALM3; ZNF274; TRAF6; MAP3K5; MAPK13; PSEN1; NGF; CAMK2D; KIDINS220; FOXO3
    Retrograde endocannabinoid signaling GNG8; PRKCG; PRKACG; GNG2; GNAQ; PRKCB; GNB2; GNG4; MAPK13; GABRP
    Dopaminergic synapse FOS; MAPK11; PPP3CB; PPP2R5D; PPP2R3A; GNAI2; ATF4; GNB1; PPP1CB; GRIA2
    Inflammatory mediator regulation of TRP channels ASIC1; PIK3CA; TRPV2; PPP1CA; MAPK10; CYP2C39; PLCB1; TRPV4; MAPK13; ASIC2
    Progesterone-mediated oocyte maturation INS2; ANAPC13; MAD2L1; MAPK1; ADCY2B; PIK3R1; CCNB1; MAPK3; CDC26; PIK3CD
    Prolactin signaling pathway SOCS6; PIK3R3; ESR1; CSN2; MAPK3; LHB; SOCS4; PIK3R5; IRF1; TH
    Amyotrophic lateral sclerosis (ALS) CASP12; PRPH; PPP3CC; NOS1; TNF; CAT; CASP9; CYCS; TRP53; Casp3
    Epithelial cell signaling in Helicobacter pylori infection ATP6V0A1; ATP6V1H; ATP6V1G1; IKBKG; ATP6V1B1; NFKB1; LYN; RAC1; NOD1; ATP6V1E2
    Shigellosis ACTG1; ATG5; BTRC; ELMO2; PFN4; U2AF1L4; IKBKG; PFN2; MAPK8; RHOG
    Salmonella infection MAPK13; CCL4L2; CDC42L; RAB7A; ROCK2B; RAB7B; CDC42L2; MAPK8; WASLA; RAC1
    Pertussis GNAI2; PYCARD; IRF8; Il23a; Il12b; CALM4; GNAI1; IL1B; MAPK8; C1QC; CALM2
    Chagas disease (American trypanosomiasis) TNF; CASP8; GNAI3; GNA11; GNAL; TLR4; IL6; NFKB1; MAPK10; IL12A
    Toxoplasmosis TRAF6; TGFB3; H2-AB1; HLA-DRB4; ALOX5; BAD; HLA-DPB1; CD40LG; LAMB4; MAP2K3
    Tuberculosis CALM3; FCER1G; SPHK1; RFX5; IFNA13; IL18; H2-AA; VDR; TGFB1; HSPA9
    Hepatitis C IFNA12; IFNA4; TP53; KRAS; CLDN15; IFNA7; IFNA8; IFNAR2; PIK3CG; EIF2AK2
    Influenza A DDX39B; IFNA6; CASP1; NXT1; NFKBIB; Ccl12; AKT2; IFNB; TNFSF10; MAPK3
    Epstein-Barr virus infection IL10RB; MAP3K14; TBK1; MAP3K7; CSNK2B; PSMC5; POLR2K; POLR2H; ITGAL; HLA-DPB1
    Proteoglycans in cancer CBL; VAV2; GPC3; MDM2; WNT7B; VTN; WNT3; FLNA; PTK2; PPP1CC

    MAPK13 has several biochemical functions, for example, ATP binding, MAP kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK13 itself. We selected most functions MAPK13 had, and list some proteins which have the same functions with MAPK13. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ATP6V1A; CDK12; G3BP1; SLFNL1; STK38; SGK2B; ATAD5; STK11; GRK1; CDK4
    MAP kinase activity MAPK6; MAPK7; MAPK1; MAPK3; MAPK12A; NLK1; MAPK12; MAPK14B; NLK; MAPK8B
    protein binding C10orf35; SPERT; METTL1; RPS10; DMC1; BCL2L16; GCC1; TAF2; APLF; FAM127C
    protein serine/threonine kinase activity TSSK1; ROCK2; BUB1B; AURKA; TLK1B; NEK12; NIM1K; BMPR1B; MAP3K12; RIOK3

    MAPK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK13.

    PRKD1; FPR1; saicar; PKM; ATF2; MAPKAPK3; Pkd1; MAP3K4; GPX4; SMAD4; ANKLE2; AKIP1; pi3p

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