• Official Full Name

    mitogen-activated protein kinase 13

  • Background

    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
  • Synonyms

    MAPK13; mitogen-activated protein kinase 13; PRKM13; p38delta; SAPK4; MAPK 13; MAP kinase 13; MAP kinase p38 delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; MGC99536;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Insect Cell
    • Insect Cells
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • SUMO
    • Myc
    • DDK
    • Myc|DDK
    • N/A
    • No tag
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK13-31H Recombinant human biotinylated MAPK13, His-tagged E.coli His
    Human MAPK13-374H Recombinant Human MAPK13, GST-tagged, Active Sf9 Insect Cell GST
    Human MAPK13-48H Recombinant Human MAPK13, GST-tagged Sf9 Insect Cell GST
    Human MAPK13-31379TH Recombinant Human MAPK13, His-tagged E.coli His
    Human MAPK13-31380TH Recombinant Human MAPK13 N/A
    Human MAPK13-2436H Recombinant Human MAPK13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MAPK13-945H Recombinant Human MAPK13 protein, GST-tagged Insect Cells GST
    Human MAPK13-3205H Recombinant Human MAPK13 protein, His-SUMO-tagged E.coli His-SUMO
    Human MAPK13-574HCL Recombinant Human MAPK13 cell lysate Insect Cell N/A
    Human MAPK13-1088H Recombinant Human MAPK13 Protein (S2-L365), Tag Free Insect Cell No tag
    Human MAPK13-383H Recombinant Human MAPK13 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human MAPK13-357H Recombinant Human MAPK13 protein, GST-tagged Insect Cells GST
    Human MAPK13-1089H Recombinant Human MAPK13 Protein (S2-L365), GST tagged Insect Cell GST
    Human MAPK13-737H Recombinant Human Mitogen-activated Protein Kinase 13 E.coli N/A
    Human MAPK13-1285H Recombinant Human Mitogen-Activated Protein Kinase 13, His-tagged Human His
    Mouse Mapk13-3940M Recombinant Mouse Mapk13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • MAPK13 Related Research Area
    • MAPK13 Related Signal Pathway

    MAPK13 involved in several pathways and played different roles in them. We selected most pathways MAPK13 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathwayFasl;MAPK8;RASGRP3;NTRK1;MAPK6;FGF8;TRAF2;PPM1B;MAPK3
    Sphingolipid signaling pathwayS1PR4;LASS1;MAPK13;RAC1;PPP2R2A;CERS2;PIK3CA;CERS5;MAPK10
    Adrenergic signaling in cardiomyocytesPPP2R5EA;RAPGEF4;ATP2B1A;ATF4;PPP2R3A;PPP2R5E;CACNG2A;PPP1CB;PPP2R2CA
    Osteoclast differentiationTYK2;FOSB;TGFB2;CALCR;IL1A;NOX3;LILRB5;MAPK9;NCF2
    Signaling pathways regulating pluripotency of stem cellsINHBB;MAPK1;ACVR1B;ACVR1C;MAP2K1;PCGF3;MAP2K2;ZFHX3;WNT10B
    Platelet activationPLA2G4D;PPP1CC;ROCK1;ROCK2;BTK;PPP1R12A;NOS3;FGG;MYL12B
    Toll-like receptor signaling pathwayTRAF6;RELA;MAPK9;CD86;NFKBIAA;CCL5;IFNA7;IL1B;TAB2
    NOD-like receptor signaling pathwayRIPK2;CASP5;MAP3K7;NAIP1;IKBKB;TAB3;TNF;CXCL2;CARD8
    RIG-I-like receptor signaling pathwayCXCL8B.3;NFKBIA;IFNA17;IL8L1;IL8L2;Ifna15;MAPK12B;MAPK13;DDX58
    T cell receptor signaling pathwayNCK1;LCP2;LAT;PAK7;IFNG;MAPK13;PLCG1;PAK6;CD3E
    Fc epsilon RI signaling pathwayTNF;PLA2G4F;PLA2G4C;PIK3CG;FCER1A;PIK3R3;LCP2;MAPK9;PIK3R1
    TNF signaling pathwayPIK3R1;CX3CL1;BAG4;NFKBIA;FADD;NFKB1;CXCL10;CCL20;PGAM5
    Leukocyte transendothelial migrationCTNNA3;ROCK2;PECAM1;MYL5;JAM3;CLDN14;RAP1A;MMP9;ITGB2
    Neurotrophin signaling pathwayARHGDIG;SHC1;IRS1;RAP1B;TP73;SHC3;PIK3CG;GAB1;CDC42
    Retrograde endocannabinoid signalingGRIA4;MAPK9;GNAO1;GNG2;PRKCG;GNAI1;GABRG2;GNAI2;GABRG3
    Dopaminergic synapseGRIA1;GNAI3;GNAQ;PPP2R5D;CREB3L1;GRIN2A;KIF5B;GSK3B;GNG5
    Inflammatory mediator regulation of TRP channelsPLCB3;PIK3R5;PPP1CB;PPP1CA;PTGER2;CALML5;TRPA1;F2RL1;PRKACA
    Progesterone-mediated oocyte maturationRAF1A;CDC25B;ADCY1B;CDC16;PRKACB;ANAPC2;ANAPC13;RAF1B;PIK3CB
    Prolactin signaling pathwaySOCS7;SOCS5;RAF1;MAPK12;PIK3CB;KRAS;NFKB1;SLC2A2;TH
    Amyotrophic lateral sclerosis (ALS)TOMM40;BAD;GRIN2C;GPX1;BAX;DAXX;GRIA2;TP53;MAP2K6
    Epithelial cell signaling in Helicobacter pylori infectionIKBKB;GIT1;MAPK9;CXCR2;MAPK11;IL-8;ATP6V0A2;CCL5;ATP6V0D1
    Salmonella infectionFOS;IL8L2;NOS2B;MAPK12A;RAC1B;IFNGR2;RHOGC;CCL4;TLR5
    Chagas disease (American trypanosomiasis)TNFRSF1A;PPP2R2D;GNA15;C1QC;CCL3;C1QA;PIK3CG;PIK3R2;C1QB
    Epstein-Barr virus infectionPOLR2L;PSMD6;FGR;PSMD12;TRADD;HSPA1L;MAP3K7;HLA-DQA2;PSMC5
    Proteoglycans in cancerSOS1;PPP1R12C;PTK2;MAPK11;IGF2;CDC42;FZD2;TWIST2;FGFR1

    MAPK13 has several biochemical functions, for example, ATP binding, MAP kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK13 itself. We selected most functions MAPK13 had, and list some proteins which have the same functions with MAPK13. You can find most of the proteins on our site.

    Function Related Protein
    MAP kinase activityMAPK15;MAPK6;MAPK12A;MAPK4;NLK;MAPK7;NLK1;MAPK14;MAPK8B
    protein bindingHOXA1;CDC26;PLUNC;TTR;LONP1;PSEN1;IL5RA;ZUFSP;ZNF26
    protein serine/threonine kinase activityGRK7B;PRKD2;SBK3;OXSR1A;MAPKAPK2;CDK14;PSKH1;CAMK2D1;MLKL

    MAPK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK13.

    PRKD1; FPR1; saicar; PKM; ATF2; MAPKAPK3; Pkd1; MAP3K4; GPX4; SMAD4; ANKLE2; AKIP1; pi3p

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