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Official Full Name mitogen-activated protein kinase 13
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Synonyms MAPK13; mitogen-activated protein kinase 13; PRKM13; p38delta; SAPK4; MAPK 13; MAP kinase 13; MAP kinase p38 delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; MGC99536
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Insect Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK13-1285H Recombinant Human Mitogen-Activated Protein Kinase 13, His-tagged Human His
    Human MAPK13-2436H Recombinant Human MAPK13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MAPK13-31379TH Recombinant Human MAPK13, His-tagged E.coli His
    Human MAPK13-31380TH Recombinant Human MAPK13 N/A
    Human MAPK13-31H Recombinant human biotinylated MAPK13, His-tagged E.coli His
    Human MAPK13-357H Recombinant Human MAPK13 Protein, GST-tagged, Activated Insect Cell GST
    Human MAPK13-374H Recombinant Human MAPK13, GST-tagged, Active Sf9 Insect Cell GST
    Human MAPK13-383H Recombinant Human MAPK13 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human MAPK13-48H Recombinant Human MAPK13, GST-tagged Sf9 Insect Cell GST
    Human MAPK13-574HCL Recombinant Human MAPK13 cell lysate Insect Cell N/A
    Human MAPK13-737H Recombinant Human Mitogen-activated Protein Kinase 13 E.coli N/A
    Human MAPK13-945H Recombinant Human MAPK13, GST tagged Insect Cell GST
    Mouse Mapk13-3940M Recombinant Mouse Mapk13 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    MAPK13 involved in several pathways and played different roles in them. We selected most pathways MAPK13 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway PPM1B; PPM1NA; STMN1B; MAPK3; GADD45AB; FGFR4; MAPK6; MAPK12A; TRP53; PRKACBA
    Rap signaling pathway PIK3CG; F2R; HGF; SIPA1L1; PRKCB; GNAI1; NGF; MAP2K3; PLCB3; FGF11
    FoxO signaling pathway TGFB3; SIRT1; MAP2K1; TGFBR2; GRB2B; SOD2; PIK3CD; GADD45B; MAPK14B; AKT2L
    Sphingolipid signaling pathway PRKCG; PPP2R2B; TNF; PPP2R1B; SMPD1; BID; LASS4; SPHK2; PLCB1; ROCK2
    Adrenergic signaling in cardiomyocytes ATP2B1; MAPK12A; CACNG3; CAMK2A; AKT3A; AKT1; MAPK14A; CACNB4A; ADCY1; CACNG8
    VEGF signaling pathway SPHK2; PRKCBA; PPP3R1B; CDC42L; RAC1B; MAPK12; CDC42L2; PLA2G4D; PLCG2; CDC42
    Osteoclast differentiation LILRA3; IL1R1; CYBA; LILRA5; RELB; NFKBIA; LILRA1; STAT1; MAPK12; FOSL1
    Signaling pathways regulating pluripotency of stem cells IGF1R; NANOG; OTX1; SKIL; PIK3CG; SMAD3; ACVR1; PAX6; ISL1; MAPK12
    Platelet activation BTK; PLA2G4A; FGB; NOS3; ITPR3; APBB1IP; SNAP23; GP5; PPP1CB; ROCK1
    Toll-like receptor signaling pathway LBP; IFNA16; IFNB; MAPK1; MAP2K4B; IL6; IFNA6; CXCL10; IL8L1; IL8L2
    NOD-like receptor signaling pathway IL8L1; PYDC1; PSTPIP1B; IKBKB; PSTPIP1A; NLRC4; MAPK8B; NAIP6; CARD8; PSTPIP1
    RIG-I-like receptor signaling pathway IFNA13; IFNA6; IFIH1; IRF3; MAPK12; IFNE; DDX3X; RELA; TANK; NFKBIAA
    T cell receptor signaling pathway NFATC2; ICOS; PIK3R5; PIK3R2; PAK6; ZAP70; CD4; TNF; PAK2; SLA1
    Fc epsilon RI signaling pathway IL13; RAC2; PIK3R5; SYK; PLCG2; GAB2; FCER1G; MAP2K1; PLA2G4D; MAPK3
    TNF signaling pathway CXCL3; TAB2; MAPK13; CXCL5; CREB5; TRAF1; CASP10; PTGS2; TRADD; SELE
    Leukocyte transendothelial migration CDC42; RAC1; MSN; PIK3CB; VASP; GNAI2; CD99; CLDN2; PIK3R3; CXCL12
    Neurotrophin signaling pathway NFKB1; PIK3R5; GSK3B; PIK3CD; MAP3K3; RPS6KA2; CAMK2G; MAPK12; PIK3R1; GRB2
    Retrograde endocannabinoid signaling PRKCB; SLC17A8; GABRA2; PLCB1; GNG7; ITPR1; GABRD; PRKCA; GNAO1; GNG13
    Dopaminergic synapse PPP2R2B; CALM3; MAPK9; SLC6A3; SCN1A; MAPK8; PLCB4; SLC18A2; KCNJ5; GNAS
    Inflammatory mediator regulation of TRP channels CYP2C55; HTR2B; MAPK10; MAPK11; PLA2G4C; ACCN4; PRKCQ; ALOX12; PLCG2; SRC
    Progesterone-mediated oocyte maturation HSP90AA1; MAPK14B; MOS; ANAPC11; IGF1; BUB1; AKT1; CDC27; PRKACB; RPS6KAL
    Prolactin signaling pathway SHC1; PIK3R2; CSN2; SOS1; SOCS3; MAPK12; MAP2K2; AKT1; MAPK9; PIK3CA
    Amyotrophic lateral sclerosis (ALS) RAC1; TRP53; TOMM40L; TNFRSF1A; TP53; ALS2; CASP1; CAT; NEFM; MAP2K3
    Epithelial cell signaling in Helicobacter pylori infection SRC; ATP6V1D; ADAM17; ATP6V0A4; ATP6V0D2; CDC42; IKBKB; ATP6V1H; ATP6V1G3; CXCR1
    Shigellosis IKBKB; U2AF1; PFN1; WASL; RAC1; VCL; CDC42; ARPC5L; SRC; ITGA5
    Salmonella infection DYNC1I1; KLC4; MAPK8A; DYNC1LI2; NFKB1; CDC42L2; MAPK10; CASPA; RAC1; CD14
    Pertussis SERPING1; CXCL5; MAPK9; PYCARD; C1R; MAPK8; Il23a; IL23; NLRP3; CASP7
    Leishmaniasis HLA-DOA; MYD88; ELK1; IRAK1; TAB2; MAP3K7; PRKCB; STAT1; Itgam&Itgb2; TGFB1
    Chagas disease (American trypanosomiasis) PLCB4; IL12A; GNAI1; IL10; MYD88; PIK3CA; IL12B; CD3G; TLR2; C1QC
    Toxoplasmosis HLA-DOB; CASP8; TAB2; PDPK1; MAPK9; HSPA8; MAP2K3; HLA-DRB4; MAP3K7; IRAK1
    Tuberculosis IFNGR2; FCGR2B; BCL2; IRAK2; MAPK12; Ifna11; HLA-DRB1; CLEC4M; FCGR3; PPP3CC
    Influenza A MAP2K4; IFNA1; RAF1; DNAJC3; IFNA10; MAVS; IFNA12; IL-8; SOCS3; Fasl
    Epstein-Barr virus infection PIK3CD; GTF2E2; TRAF5; HSPB1; GSK3B; MAP2K6; FGR; RIPK1; POLR2K; MAP3K7
    Proteoglycans in cancer ITPR3; STAT3; SMAD2; PLAU; CAV1; CD63; CCND1; MSN; ANK2; ROCK1

    MAPK13 has several biochemical functions, for example, ATP binding, MAP kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK13 itself. We selected most functions MAPK13 had, and list some proteins which have the same functions with MAPK13. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ACTC1; LMTK3; PRKACAA; ATP1A1; MAP3K14; NLRC3; MAP3K9; MYHZ1.2; ERN2; UBE2L3B
    MAP kinase activity MAPK13; MAPK14; MAPK3; NLK1; MAPK4; MAPK14A; MAPK12B; NLK; MAPK11; MAPK7
    protein binding HNRNPA1; WLS; KLHDC5; COG7; ACOT7; MRPL10; CCNDBP1; TMEM115; SKP1; RING1
    protein serine/threonine kinase activity MAP2K7; LMTK2; MAPK12B; CAMKK1B; DYRK4; STRC; ACVR1L; DYRK2; SGK2B; KALRN

    MAPK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK13.

    PRKD1; FPR1; saicar; PKM; ATF2; MAPKAPK3; Pkd1; MAP3K4; GPX4; SMAD4; ANKLE2; AKIP1; pi3p

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