MAPK13 Protein

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MAPK13

Official Full Name	mitogen-activated protein kinase 13
Background	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Synonyms	MAPK13; mitogen-activated protein kinase 13; PRKM13; p38delta; SAPK4; MAPK 13; MAP kinase 13; MAP kinase p38 delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; MGC99536

Species :
Human
Mouse

Source :
E.coli
HEK293
HEK293T
Human
Insect Cell
Sf9 Insect Cell

Tag :
GST
His
His-SUMO
Myc/DDK
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	MAPK13-357H	Active Recombinant Human MAPK13 Protein, GST-tagged, Activated	Insect Cell	GST	Inquiry
Human	MAPK13-1285H	Recombinant Human Mitogen-Activated Protein Kinase 13, His-tagged	Human	His	Inquiry
Human	MAPK13-31379TH	Recombinant Human MAPK13, His-tagged	E.coli	His	Inquiry
Human	MAPK13-31380TH	Recombinant Human MAPK13		N/A	Inquiry
Human	MAPK13-31H	Recombinant human biotinylated MAPK13, His-tagged	E.coli	His	Inquiry
Human	MAPK13-374H	Recombinant Human MAPK13, GST-tagged, Active	Sf9 Insect Cell	GST	Inquiry
Human	MAPK13-48H	Recombinant Human MAPK13, GST-tagged	Sf9 Insect Cell	GST	Inquiry
Human	MAPK13-737H	Recombinant Human Mitogen-activated Protein Kinase 13	E.coli	N/A	Inquiry
Human	MAPK13-945H	Recombinant Human MAPK13, GST tagged	Insect Cell	GST	Inquiry
Human	MAPK13-574HCL	Recombinant Human MAPK13 cell lysate	Insect Cell	N/A	Inquiry
Human	MAPK13-1297HF	Recombinant Full Length Human MAPK13 Protein, GST-tagged	E.coli	GST	Inquiry
Human	MAPK13-3205H	Recombinant Human MAPK13 protein, His-SUMO-tagged	E.coli	His-SUMO	Inquiry
Human	MAPK13-2436H	Recombinant Human MAPK13 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Human	MAPK13-383H	Recombinant Human MAPK13 Protein, MYC/DDK-tagged	HEK293	Myc/DDK	Inquiry
Mouse	Mapk13-3940M	Recombinant Mouse Mapk13 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry

Involved Pathway Protein Function Interacting Protein

MAPK13 involved in several pathways and played different roles in them. We selected most pathways MAPK13 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
MAPK signaling pathway	MAP2K3; ECSIT; RAC3A; CACNA2D2; CACNA1BA; MAPK8IP3; PPP3R2; ARR3B; CACNG7; CACNA1D
Rap signaling pathway	PFN3; LPAR3; FGF4; MAGI1; PRKD3; RAF1; MAPK13; RAPGEF6; GRIN1; ITGB2L
FoxO signaling pathway	GRB2B; SIRT1; FBXO25; IGF1RB; CCND2A; EGFRA; PRMT1; MAPK14A; SGK2A; PCK2
Sphingolipid signaling pathway	PIK3R2; SPHK2; PPP2R1B; PRKCE; TNF; PPP2R5C; RAC2; BDKRB2; CERS4; SPTLC3
Adrenergic signaling in cardiomyocytes	MAPK14A; PPP2R2C; FXYD2; PPP2R5B; VMHC; PPP2R1B; ATP2B1; CACNB4A; PRKACBA; CACNG2A
VEGF signaling pathway	PTK2AA; PXN; NRAS; PRKCBA; PLA2G4A; CDC42L; SHC2; MAP2K2A; PPP3R2; PTGS2B
Osteoclast differentiation	MITF; LILRB1; NOX3; AKT2; PIK3R3; TGFB1; FCGR2A; SIRPA; LILRA2; RAC1
Signaling pathways regulating pluripotency of stem cells	PIK3R3; HESX1; MAPK12; WNT6; SMARCAD1; WNT2; APC; DLX5; PIK3CG; WNT9A
Platelet activation	GNAI2; PLCB4; PLCG2; PIK3R3; GUCY1A3; MAPK13; PIK3CD; PRKG1; ROCK2; VAMP8
Toll-like receptor signaling pathway	IFNPHI3; TLR3; MAP2K4; SPP1; CASP8; IFNA16; TLR8; TRAF3; RAC1A; MAPK10
NOD-like receptor signaling pathway	RIPK2; HSP90AA1.2; TNFAIP3; CXCL8B.3; RELA; IL8L1; TAB2; IL1B; TRAF6; NLRP1
RIG-I-like receptor signaling pathway	Ifna11; MAP3K7; MAPK9; IFNA8; IL12B; IFNPHI1; NFKBIAA; IFNA2; RNF207B; IFIH1
T cell receptor signaling pathway	VAV2; SHB; CD3G; PPP3R1; NCK1; CD8A; TEC; PAK2; PDPK1; MAP2K7
Fc epsilon RI signaling pathway	KRAS; BTK; RAC3; PLCG1; SOS1; GAB2; INPP5D; MAP2K2; TNF; GM-CSF
TNF signaling pathway	TRAF3; MAPK9; MAP2K6; TRAF2; IL6; BAG4; CXCL5; PIK3R2; MAP2K7; IKBKG
Leukocyte transendothelial migration	CYBB; EZR; ACTN4; TXK; ACTN3; PLCG2; CLDN23; MYL10; JAM3; PIK3CG
Neurotrophin signaling pathway	CALM3; ZNF274; TRAF6; MAP3K5; MAPK13; PSEN1; NGF; CAMK2D; KIDINS220; FOXO3
Retrograde endocannabinoid signaling	GNG8; PRKCG; PRKACG; GNG2; GNAQ; PRKCB; GNB2; GNG4; MAPK13; GABRP
Dopaminergic synapse	FOS; MAPK11; PPP3CB; PPP2R5D; PPP2R3A; GNAI2; ATF4; GNB1; PPP1CB; GRIA2
Inflammatory mediator regulation of TRP channels	ASIC1; PIK3CA; TRPV2; PPP1CA; MAPK10; CYP2C39; PLCB1; TRPV4; MAPK13; ASIC2
GnRH signaling pathway	HRASB; MAPK10; PLA2G4AA; GNRHR4; PRKACBA; CALM1; PRKACAA; PRKCBB; MAP2K2; PLCB3
Progesterone-mediated oocyte maturation	INS2; ANAPC13; MAD2L1; MAPK1; ADCY2B; PIK3R1; CCNB1; MAPK3; CDC26; PIK3CD
Prolactin signaling pathway	SOCS6; PIK3R3; ESR1; CSN2; MAPK3; LHB; SOCS4; PIK3R5; IRF1; TH
Amyotrophic lateral sclerosis (ALS)	CASP12; PRPH; PPP3CC; NOS1; TNF; CAT; CASP9; CYCS; TRP53; Casp3
Epithelial cell signaling in Helicobacter pylori infection	ATP6V0A1; ATP6V1H; ATP6V1G1; IKBKG; ATP6V1B1; NFKB1; LYN; RAC1; NOD1; ATP6V1E2
Shigellosis	ACTG1; ATG5; BTRC; ELMO2; PFN4; U2AF1L4; IKBKG; PFN2; MAPK8; RHOG
Salmonella infection	MAPK13; CCL4L2; CDC42L; RAB7A; ROCK2B; RAB7B; CDC42L2; MAPK8; WASLA; RAC1
Pertussis	GNAI2; PYCARD; IRF8; Il23a; Il12b; CALM4; GNAI1; IL1B; MAPK8; C1QC; CALM2
Leishmaniasis	HLA-DPB1; NFKBIA; MAPK3; CYBA; H2-AB1; ITGA4; NFKBIB; IFNGR2; TGFB2; HLA-DMB
Chagas disease (American trypanosomiasis)	TNF; CASP8; GNAI3; GNA11; GNAL; TLR4; IL6; NFKB1; MAPK10; IL12A
Toxoplasmosis	TRAF6; TGFB3; H2-AB1; HLA-DRB4; ALOX5; BAD; HLA-DPB1; CD40LG; LAMB4; MAP2K3
Tuberculosis	CALM3; FCER1G; SPHK1; RFX5; IFNA13; IL18; H2-AA; VDR; TGFB1; HSPA9
Hepatitis C	IFNA12; IFNA4; TP53; KRAS; CLDN15; IFNA7; IFNA8; IFNAR2; PIK3CG; EIF2AK2
Influenza A	DDX39B; IFNA6; CASP1; NXT1; NFKBIB; Ccl12; AKT2; IFNB; TNFSF10; MAPK3
Epstein-Barr virus infection	IL10RB; MAP3K14; TBK1; MAP3K7; CSNK2B; PSMC5; POLR2K; POLR2H; ITGAL; HLA-DPB1
Proteoglycans in cancer	CBL; VAV2; GPC3; MDM2; WNT7B; VTN; WNT3; FLNA; PTK2; PPP1CC

MAPK13 has several biochemical functions, for example, ATP binding, MAP kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK13 itself. We selected most functions MAPK13 had, and list some proteins which have the same functions with MAPK13. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	ATP6V1A; CDK12; G3BP1; SLFNL1; STK38; SGK2B; ATAD5; STK11; GRK1; CDK4
MAP kinase activity	MAPK6; MAPK7; MAPK1; MAPK3; MAPK12A; NLK1; MAPK12; MAPK14B; NLK; MAPK8B
protein binding	C10orf35; SPERT; METTL1; RPS10; DMC1; BCL2L16; GCC1; TAF2; APLF; FAM127C
protein serine/threonine kinase activity	TSSK1; ROCK2; BUB1B; AURKA; TLK1B; NEK12; NIM1K; BMPR1B; MAP3K12; RIOK3

MAPK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK13.

PRKD1; FPR1; saicar; PKM; ATF2; MAPKAPK3; Pkd1; MAP3K4; GPX4; SMAD4; ANKLE2; AKIP1; pi3p

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MAPK13 Protein

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MAPK13

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