RPS27A

  • Official Full Name

    ribosomal protein S27a

  • Overview

    Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
  • Synonyms

    RPS27A; ribosomal protein S27a; ubiquitin-40S ribosomal protein S27a; S27A; Uba80; UBCEP80; ubiquitin carboxyl extension protein 80; ubiquitin C; ubiquitin-CEP80; 40S ribosomal protein S27a; ubiquitin and ribosomal protein S27a; UBC; CEP80; UBCEP1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Human
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RPS27A-487H Active Recombinant Human RPS27A E.coli N/A
Human RPS27A-18H Recombinant Human Ubiquitin, G76A Mutation E.coli N/A
Human RPS27A-2424H Recombinant Human RPS27A, His-tagged E.coli His 1-156aa
Human RPS27A-4666H Recombinant Human Ribosomal Protein S27a, GST-Tagged Human GST
Human RPS27A-79H Recombinant Human Ribosomal Protein S27a E.coli N/A
Human RPS27A-19H Recombinant Human Ubiquitin, K48R Mutation E.coli N/A
Human RPS27A-2165HCL Recombinant Human RPS27A 293 Cell Lysate HEK293 N/A
Human RPS27A-003H Recombinant Human RPS27A Protein E.coli
Human RPS27A-004H Recombinant Human RPS27A Protein, His-tagged E.coli His
Mouse RPS27A-14485M Recombinant Mouse RPS27A Protein Mammalian Cell His
Mouse RPS27A-7784M-B Recombinant Mouse RPS27A Protein Pre-coupled Magnetic Beads HEK293
Mouse RPS27A-7784M Recombinant Mouse RPS27A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RPS27A-5165R Recombinant Rat RPS27A Protein Mammalian Cell His
Rat RPS27A-4824R Recombinant Rat RPS27A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RPS27A-4824R-B Recombinant Rat RPS27A Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RPS27A-4021R Recombinant Rhesus monkey RPS27A Protein, His-tagged Mammalian Cell His
Rhesus Macaque RPS27A-3838R Recombinant Rhesus Macaque RPS27A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RPS27A-3838R-B Recombinant Rhesus Macaque RPS27A Protein Pre-coupled Magnetic Beads HEK293
Zebrafish RPS27A-10796Z Recombinant Zebrafish RPS27A Mammalian Cell His
Chicken RPS27A-5486C Recombinant Chicken RPS27A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RPS27A involved in several pathways and played different roles in them. We selected most pathways RPS27A participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS27A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RibosomeMRPL21;RPLP1;MRPS16;MRPL30;RPS15;MRPL16;RPL23;RPS27.2;RPS28

RPS27A has several biochemical functions, for example, metal ion binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS27A itself. We selected most functions RPS27A had, and list some proteins which have the same functions with RPS27A. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingZBTB7C;ADO;TGM2;CA15A;TNNC1;AMDHD2;ZC3H11A;MAT2AA;RARAA
poly(A) RNA bindingNDUFV3;RTF1;TPD52L2;HIST1H1C;NOM1;RBMS2;KIF1C;CORO1A;DROSHA
protein bindingMYH7B;DEFA6;IGHMBP2;KIAA0408;P2RY1;LGALS13;FOXB1;HEMGN;NUDT12
structural constituent of ribosomeRPS20;FAUB;MRPL3;RPL29;RPL26L1;RPS4X;RPL36A;RPL7A;RPL26

RPS27A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS27A here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS27A.

DAZAP2; CALCOCO2; TNFRSF1A; MAP3K3; TRAF6; CDK11B; MDM2; KANSL3; RNF11; midostaurin; GABARAP; TP53; VCL; RPL10

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