RPS6KA1 Protein


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Official Full Name ribosomal protein S6 kinase, 90kDa, polypeptide 1
Background RSK 1 (p90-RSK 1) is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes RSK 1, RSK 2 and RSK 3. These are broadly expressed serine/threonine protein kinases (1) activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2 (2). p90-RSK 1 is activated by MAPK in vitro and in vivo via phosphorylation (3). Active RSKs appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB (2,4).
Synonyms RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; ribosomal protein S6 kinase alpha-1; HU 1; RSK; RSK1; RSK-1; p90S6K; p90RSK1; p90-RSK 1; MAPKAPK-1a; S6K-alpha 1; S6K-alpha-1; MAPKAP kinase 1a; ribosomal S6 kinase 1; MAPK-activated protein kinase 1a; ribosomal protein S6 kinase alpha 1; 90 kDa ribosomal protein S6 kinase 1; MAP kinase-activated protein kinase 1a; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; MAPKAPK1A
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RPS6KA1-3984H Recombinant Human RPS6KA1 protein, His-tagged E.coli His
    Human RPS6KA1-1934H Recombinant Human RPS6KA1 protein, His & T7-tagged E.coli His/T7
    Human RPS6KA1-2162HCL Recombinant Human RPS6KA1 293 Cell Lysate HEK293 N/A
    Human RPS6KA1-2432H Recombinant Human RPS6KA1, GST-tagged E.coli GST
    Human RPS6KA1-30110TH Recombinant Human RPS6KA1 N/A
    Human RPS6KA1-424H Recombinant Human RPS6KA1, GST-tagged, Active Sf9 Insect Cell GST
    Human RPS6KA1-4414H Recombinant Human RPS6KA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human RPS6KA1-550H Recombinant Human RPS6KA1 Mammalian Cell His
    Human RPS6KA1-555H Recombinant Human RPS6KA1, GST-tagged Sf9 Insect Cell GST
    Mouse Rps6ka1-5609M Recombinant Mouse Rps6ka1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat RPS6KA1-5172R Recombinant Rat RPS6KA1 Protein Mammalian Cell His
    Chicken RPS6KA1-3760C Recombinant Chicken RPS6KA1 Mammalian Cell His
    Zebrafish RPS6KA1-4852Z Recombinant Zebrafish RPS6KA1 Mammalian Cell His

    RPS6KA1 involved in several pathways and played different roles in them. We selected most pathways RPS6KA1 participated on our site, such as MAPK signaling pathway, Oocyte meiosis, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS6KA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FGF22; HSPA1L; CACNA1BA; FGFR4; PPP3R1B; MAP2K5; PRKACBB; FGF10; CACNA1D; TRAF6
    mTOR signaling pathway INS2; RPS6KA1; TSC1B; RICTOR; RPS6KB2; RPS6KB1; PIK3CG; POLDIP3; INSB; PRKCA
    Long-term potentiation EP300; CAMK2B; MAP2K1; CALM4; PLCB2; PRKACA; PRKACG; PPP1R1A; ATF4; RPS6KA6
    Neurotrophin signaling pathway MAPK10; BCL2; MAP2K2; ATF4; IKBKB; MATK; ARHGDIB; MAP2K7; RPS6KA3; TRAF6
    Progesterone-mediated oocyte maturation ANAPC5; MAD2L1; MOS; IGF1RB; ANAPC7; CCNB3; CDK1; MAPK10; PIK3CA; CDC25C
    Insulin resistance INSR; CREB3L3A; SLC27A3; ACACB; RPS6KB2; RPS6KA3B; GFPT2; CREB3L2; RELA; AKT3A

    RPS6KA1 has several biochemical functions, for example, ATP binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS6KA1 itself. We selected most functions RPS6KA1 had, and list some proteins which have the same functions with RPS6KA1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding NEK11; KITA; MKNK2B; PIF1; NADSYN1; AKT2L; SNRK; CDK13; DDX54; MYO10
    cysteine-type endopeptidase inhibitor activity involved in apoptotic process ARRB1; PRDX5; BIRC3; BIRC8; NOL3; VIL1; PRDX3; BIRC2; TFAP2B; GAS6
    magnesium ion binding DCTPP1; ATP11A; STK11; PTENB; ABL2; ENOPH1; PGM5; SIK2; TDP2B; ZNF143B
    protein binding IFT20; VEGFC; STYK1; NUMA1; TLE1; ACTL6A; LYN; GABBR1; WBP11; C2orf65
    protein serine/threonine kinase activity MAPKAPK2; CAMK2A; MAP3K11; TAOK3; MAPK8; CAMK2B1; SBK3; PSKH1; STK38; MAPK1
    protein serine/threonine/tyrosine kinase activity TTK; AURKA; MAP2K2; TESK2; DYRK4; PRKACA; DYRK2; RPS6KA2; RPS6KA1; RPS6KB1
    ribosomal protein S6 kinase activity RPS6KA3A; RPS6KA3; RPS6KB2; RPS6KB1B; RPS6KA4; RPS6KA3B; ALPK2; RPS6KA6; RPS6KA1; RPS6KB1

    RPS6KA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS6KA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS6KA1.

    HSP90AB1; VASP; MAPT; CREB1; EIF4B; RPS6; xmd8-92; biotin_acyl-p_probe; YWHAB; ENAH; PPM1G; DDAH2; CFL1; GBP2; TTK; CCT4

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