RPS6KA2 Protein


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Official Full Name ribosomal protein S6 kinase, 90kDa, polypeptide 2
Background This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms RPS6KA2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; RSK; HU-2; RSK3; p90-RSK3; pp90RSK3; MAPKAPK1C; S6K-alpha; S6K-alpha2; ribosomal protein S6 kinase alpha-2; RSK-3; p90RSK2; p90-RSK 2; MAPKAPK-1c; S6K-alpha-2; MAPKAP kinase 1c; ribosomal S6 kinase 3; MAPK-activated protein kinase 1c; ribosomal protein S6 kinase alpha 2; 90 kDa ribosomal protein S6 kinase 2; MAP kinase-activated protein kinase 1c; ribosomal protein S6 kinase 90kDa polypeptide 2;
    • Species :
    • Cynomolgus Monkey
    • Human
    • Source :
    • E.coli
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RPS6KA2-2433H Recombinant Human RPS6KA2, His-tagged E.coli His
    Human RPS6KA2-3740H Recombinant Human RPS6KA2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human RPS6KA2-426H Recombinant Human RPS6KA2, GST-tagged, Active Sf9 Insect Cell GST
    Human RPS6KA2-610HCL Recombinant Human RPS6KA2 cell lysate Insect Cell N/A
    Human RPS6KA2-961H Recombinant Human RPS6KA2, GST tagged Insect Cell GST
    Cynomolgus Monkey RPS6KA2-887C Recombinant Cynomolgus RPS6KA2 Protein, His-tagged Mammalian Cell His

    RPS6KA2 involved in several pathways and played different roles in them. We selected most pathways RPS6KA2 participated on our site, such as MAPK signaling pathway, Oocyte meiosis, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS6KA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway PPM1AB; CACNA1H; PPP3R1B; MAP3K11; NFKB1; MAP2K2; PDGFRA; RAC1B; IL1A; TAOK2
    Oocyte meiosis CAMK2D1; PLK1; PPP2R5EA; CAMK2G; CDC16; CDC23; CALM3B; PPP2R1A; PLCZ1; CALM3
    mTOR signaling pathway RPS6KB2; INS; AKT1; PDPK1B; RPTOR; DEPDC6; PIK3CG; RPS6KA2; PRKAA2; RPS6
    Long-term potentiation GRIA1; MAPK3; RPS6KA6; CAMK2G; GRIN2A; PRKCB; ITPR1; CAMK2B; PRKACA; CAMK4
    Neurotrophin signaling pathway IKBKB; CAMK2G; SH2B3; ZFP110; RPS6KA1; GAB1; MAP2K5; CALML3; BDNF; CAMK2D
    Progesterone-mediated oocyte maturation PRKACAA; CDC26; IGF1; PIK3R2; PLK1; PRKACBB; ANAPC1; MAPK8B; PGR; RAF1A
    Insulin resistance MAPK9; G6PC2; CREB3L3A; PIK3R1; NR1H2; CREB3L2; PTPN1; PCK1; PRKCZ; PPARAB

    RPS6KA2 has several biochemical functions, for example, ATP binding, magnesium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS6KA2 itself. We selected most functions RPS6KA2 had, and list some proteins which have the same functions with RPS6KA2. You can find most of the proteins on our site.

    Function Related Protein
    magnesium ion binding CLYBL; PTENA; MTPAP; TOP2A; PRTFDC1; ATP9B; FARSB; RPS6KA6; NT5C1B; CIB2
    protein binding KRTAP2-3; APP; PLD2; FGFRL1B; RNF168; MAPK15; MDM4; SCG5; KRT40; OTULIN
    protein serine/threonine kinase activity MAST4; ACVR1L; PRKCDA; ADCK5; MAP2K5; STK35; NLK1; MAP2K6; PDIK1L; TSSK6
    protein serine/threonine/tyrosine kinase activity PRKACA; ACVR2B; RPS6KA1; AKT1; TTK; AURKC; TESK2; DYRK4; CLK4; DSTYK
    ribosomal protein S6 kinase activity RPS6KA3A; RPS6KA3; RPS6KA2; RPS6KB2; RPS6KA6; RPS6KA3B; RPS6KA1; ALPK2; RPS6KB1; RPS6KA4

    RPS6KA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS6KA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS6KA2.

    MAPK3; MAPK1; saicar; PKM; RPS6; HSP90AB1; BRAF; PRKCA; PRKCE; CSNK2B; FLNC; 15-deoxy-delta(12,14; bosutinib; imatinib; GRSF1; FAT1

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