TAF8

This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

TAF8; TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa; TATA box binding protein (TBP) associated factor, RNA polymerase II, A, 45/50kDa , taube nuss homolog (mouse) , TBN; transcription initiation factor TFIID subunit 8; FLJ32821; TAF(II)43; hTAFII43; Protein taube nuss; TAF8 RNA polymerase II, TATA box binding protein (TBP) associated factor, 43kDa; TAF8_HUMAN; TAFII-43; TAFII43; TATA box binding protein (TBP) associated factor, RNA polymerase II A 45/50kDa; Taube nuss homolog (mouse); TBN; TBP associated factor 8; TBP associated factor TAFII43; TBP associated factor, RNA polymerase II, 43 kD; TBP-associated factor 43 kDa; TBP-associated factor 8; Transcription initiation factor TFIID 43 kDa subunit; taube nuss homolog; TBP-associated factor TAFII43; TBP-associated factor, RNA polymerase II, 43 kD; TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa; 43; II; TAF;