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VPS36

Official Full Name

vacuolar protein sorting 36 homolog (S. cerevisiae)
Overview

VPS36, VPS22 (SNF8; MIM 610904), and VPS25 (MIM 610907) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. VPS36, VPS22, and VPS25 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005
Synonyms

VPS36; vacuolar protein sorting 36 homolog (S. cerevisiae); C13orf9, chromosome 13 open reading frame 9 , vacuolar protein sorting 36 homolog (yeast); vacuolar protein-sorting-associated protein 36; CGI 145; Eap45; C13orf9; ELL associated protein of 45 kDa; ELL-associated protein of 45 kDa; ESCRT-II complex subunit VPS36; Vacuolar protein sorting associated protein 36; VPS36_HUMAN; ELL-associated protein, 45 kDa; CGI-145;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	VPS36-3679H	Recombinant Human VPS36, His-tagged	E.coli	His	1-386aa	$319 / 25μg
Human	VPS36-388HCL	Recombinant Human VPS36 293 Cell Lysate	HEK293	Non		Inquiry
Human	VPS36-1808H	Recombinant Human VPS36 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Mouse	Vps36-6939M	Recombinant Mouse Vps36 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Zebrafish	VPS36-10340Z	Recombinant Zebrafish VPS36	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

VPS36 involved in several pathways and played different roles in them. We selected most pathways VPS36 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS36 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Endocytosis	VPS26B;EEA1;CHMP2BB;ARPC4L;LDLR;EHD1B;ARPC1A;CBLC;PML

VPS36 has several biochemical functions, for example, phosphatidylinositol-3-phosphate binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS36 itself. We selected most functions VPS36 had, and list some proteins which have the same functions with VPS36. You can find most of the proteins on our site.

Function	Related Protein
phosphatidylinositol-3-phosphate binding	WDR45L;ZFYVE19;BBS5;ZFYVE28;VPS36;JPH2;PHLDA3;SNX21;ZFYVE26
protein C-terminus binding	DLG4;STIP1;YAP1;PPM1A;PDZD11;AP2A1;CEP135;PEX10;TJP2
protein binding	PXN;TMED1;USP19;NUTF2;ATL1;ITPKB;CSTF1;HMOX2;KRT18
ubiquitin binding	TOM1L1;USP16;OTUB1B;USP5;BRAP;NBR1;TRIM32;UBXN11;NEDD4

VPS36 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS36 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS36.

GCNT1; pi3p; CDC5L; Vps25; Snf8

Research Area

Herdegen, S; Conte, C; et al. Immediate and Persistent Transcriptional Correlates of Long-Term Sensitization Training at Different CNS Loci in Aplysia californica. PLOS ONE 9:-(2014).

Herdegen, S; Holmes, G; et al. Characterization of the rapid transcriptional response to long-term sensitization training in Aplysia californica. NEUROBIOLOGY OF LEARNING AND MEMORY 116:27-35(2014).