VPS41

  • Official Full Name

    vacuolar protein sorting 41 homolog (S. cerevisiae)

  • Background

    Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.
  • Synonyms

    VPS41; vacuolar protein sorting 41 homolog (S. cerevisiae); vacuolar protein sorting 41 (yeast homolog) , vacuolar protein sorting 41 (yeast); vacuolar protein sorting-associated protein 41 homolog; HVSP41; HVPS41; hVps41p; S53; Vacuolar assembly protein 41; Vacuolar protein sorting 41 (yeast homolog); Vacuolar protein sorting 41 (yeast); Vacuolar protein sorting associated protein 41 homolog; VPS 41;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken VPS41-2078C Recombinant Chicken VPS41 Mammalian Cell His
    Human VPS41-385HCL Recombinant Human VPS41 293 Cell Lysate HEK293 N/A
    Human VPS41-386HCL Recombinant Human VPS41 293 Cell Lysate HEK293 N/A
    Human VPS41-3682H Recombinant Human VPS41, His-tagged E.coli His
    Mouse VPS41-18378M Recombinant Mouse VPS41 Protein Mammalian Cell His
    Mouse Vps41-6942M Recombinant Mouse Vps41 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse VPS41-10070M-B Recombinant Mouse VPS41 Protein Pre-coupled Magnetic Beads HEK293
    Mouse VPS41-10070M Recombinant Mouse VPS41 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • VPS41 Related Articles

    VPS41 involved in several pathways and played different roles in them. We selected most pathways VPS41 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    VPS41 has several biochemical functions, for example, GTPase binding, identical protein binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS41 itself. We selected most functions VPS41 had, and list some proteins which have the same functions with VPS41. You can find most of the proteins on our site.

    Function Related Protein
    GTPase bindingGOLGA4;GM5506;AIMP1;STOML2;SH3GL1;VPS41;MARCH5;YBX1;RAB3D
    identical protein bindingUBE4A;HOMER1;GRIK5;G6PDX;MNS1;ZNF3;SNX33;FADD;PDCD6
    microtubule bindingRGS14;SPAST;ARHGEF2;REEP1;AKAP1;TPPP;CETN2;SKA1;PAFAH1B1A
    molecular_functionTRAM1L1;MUM1L1;CPNE2;SH3RF3;FAM46AB;FAM184A;DEFB30;CEACAM1;MPV17
    protein bindingTRAFD1;HMGB1;PLXND1;COG7;TMEM185A;BRCA2;MOCS3;CCDC155;KIRREL3
    zinc ion bindingBMP1B;APOBEC3D;LMO7B;MYT1LA;POLE;MMP2;QPCT;ZDHHC9;BMI1B

    VPS41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS41 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS41.

    VIPAS39; RILP; VPS18; HSP90AB1; MON1B; UBE2U; ZNF512B; Max; KDM5C; ESR2

    Ibarrola-Villava, M; Kumar, R; et al. Genes involved in the WNT and vesicular trafficking pathways are associated with melanoma predisposition. INTERNATIONAL JOURNAL OF CANCER 136:2109-2119(2015).
    Lin, XS; Yang, T; et al. RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking. SCIENTIFIC REPORTS 4:-(2014).
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