VPS41
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Official Full Name
vacuolar protein sorting 41 homolog (S. cerevisiae) -
Overview
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. -
Synonyms
VPS41;vacuolar protein sorting 41 homolog (S. cerevisiae);vacuolar protein sorting 41 (yeast homolog) , vacuolar protein sorting 41 (yeast);vacuolar protein sorting-associated protein 41 homolog;HVSP41;HVPS41;hVps41p;S53;Vacuolar assembly protein 41;Vacuolar protein sorting 41 (yeast homolog);Vacuolar protein sorting 41 (yeast);Vacuolar protein sorting associated protein 41 homolog;VPS 41
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| VPS41-3682H | Recombinant Human VPS41, His-tagged | E.coli | Human | His | 504-854aa | |
| VPS41-18378M | Recombinant Mouse VPS41 Protein | Mammalian Cells | Mouse | His |
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| VPS41-2078C | Recombinant Chicken VPS41 | Mammalian Cells | Chicken | His |
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| VPS41-385HCL | Recombinant Human VPS41 293 Cell Lysate | HEK293 | Human | Non |
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| VPS41-386HCL | Recombinant Human VPS41 293 Cell Lysate | HEK293 | Human | Non |
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| VPS41-10070M | Recombinant Mouse VPS41 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| VPS41-10070M-B | Recombinant Mouse VPS41 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Vps41-6942M | Recombinant Mouse Vps41 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
VPS41 involved in several pathways and played different roles in them. We selected most pathways VPS41 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
VPS41 has several biochemical functions, for example, GTPase binding,identical protein binding,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS41 itself. We selected most functions VPS41 had, and list some proteins which have the same functions with VPS41. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase binding | HSP90AA1,GNB1,MARCH5,GNB2,YBX1,GNB3,PTPRN,ENO1,GM5506,GOLGA4 |
| microtubule binding | PEX14,PAFAH1B1,APC2,CKAP5,KIF16B,MAPRE2,TRAF3IP1,SNCA,CHP,TRPV4 |
| protein binding | APOD,LIMD1,ZNF695,ASB13,STUB1,CEP290,NXF2,KCNJ4,ACD,LPL |
| zinc ion binding | GTF2H2,CPA5,RBCK1,PPARAA,TRIM37,LNX2A,GATA1A,BAZ2A,LMO4A,MYLIPA |
| identical protein binding | TP53,GRASP,VIM,RYR2,MCM10,GSTM3,CEACAM16,CNTN2,TFRC,C10orf88 |
| molecular_function | CYB5R1,TMEM120A,FAM89A,VPS51,GM5887,ATG2A,CEP55L,RHOX2E,LRIG2,PRRG4 |
Interacting Protein
VPS41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS41 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS41.
VIPAS39;RILP;VPS18;HSP90AB1;MON1B;UBE2U;ZNF512B;Max;KDM5C;ESR2
Resources
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References
- Lin, XS; Yang, T; et al. RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking. SCIENTIFIC REPORTS 4:-(2014).
- Ibarrola-Villava, M; Kumar, R; et al. Genes involved in the WNT and vesicular trafficking pathways are associated with melanoma predisposition. INTERNATIONAL JOURNAL OF CANCER 136:2109-2119(2015).
