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VPS41

Official Full Name

vacuolar protein sorting 41 homolog (S. cerevisiae)
Overview

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.
Synonyms

VPS41; vacuolar protein sorting 41 homolog (S. cerevisiae); vacuolar protein sorting 41 (yeast homolog) , vacuolar protein sorting 41 (yeast); vacuolar protein sorting-associated protein 41 homolog; HVSP41; HVPS41; hVps41p; S53; Vacuolar assembly protein 41; Vacuolar protein sorting 41 (yeast homolog); Vacuolar protein sorting 41 (yeast); Vacuolar protein sorting associated protein 41 homolog; VPS 41;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	VPS41-3682H	Recombinant Human VPS41, His-tagged	E.coli	His	504-854aa	$319 / 25μg
Human	VPS41-386HCL	Recombinant Human VPS41 293 Cell Lysate	HEK293	Non		Inquiry
Human	VPS41-385HCL	Recombinant Human VPS41 293 Cell Lysate	HEK293	Non		Inquiry
Mouse	VPS41-18378M	Recombinant Mouse VPS41 Protein	Mammalian Cell	His		Inquiry
Mouse	Vps41-6942M	Recombinant Mouse Vps41 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Mouse	VPS41-10070M-B	Recombinant Mouse VPS41 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	VPS41-10070M	Recombinant Mouse VPS41 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Chicken	VPS41-2078C	Recombinant Chicken VPS41	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

VPS41 involved in several pathways and played different roles in them. We selected most pathways VPS41 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

VPS41 has several biochemical functions, for example, GTPase binding, identical protein binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS41 itself. We selected most functions VPS41 had, and list some proteins which have the same functions with VPS41. You can find most of the proteins on our site.

Function	Related Protein
GTPase binding	RASA1;GOLGA4;LCP1;YBX1;RAB3D;AIMP1;PTPRN;SH3GL1;ENO1
identical protein binding	KHDC1A;ZHX2;IGF2R;ANXA4;OMG;CEP170L;NME1;SRI;FAS
microtubule binding	KIF5AA;TUBGCP5;KATNB1;KIF3B;KLC3;DPYSL5A;WDR81;MAP1LC3C;KIFC3
molecular_function	CPNE9;SPRR2A2;GLIPR2L;MORC4;EMC10;GRINAA;REEP5;ARRDC2;CFC1
protein binding	POP1;MED20;LMO4;CLIC1;ACP1;C4orf33;PGAP2;OPRD1;STAM
zinc ion binding	BTR06;USP45;PHF17;ADAMTS18;RNF222;ADAM19;CA13;RNF11A;SP140L

VPS41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS41 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS41.

VIPAS39; RILP; VPS18; HSP90AB1; MON1B; UBE2U; ZNF512B; Max; KDM5C; ESR2

Research Area

Ibarrola-Villava, M; Kumar, R; et al. Genes involved in the WNT and vesicular trafficking pathways are associated with melanoma predisposition. INTERNATIONAL JOURNAL OF CANCER 136:2109-2119(2015).

Lin, XS; Yang, T; et al. RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking. SCIENTIFIC REPORTS 4:-(2014).