WDR5

  • Official Full Name

    WD repeat domain 5

  • Overview

    This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
  • Synonyms

    WDR5; WD repeat domain 5; SWD3; BIG-3; WD repeat-containing protein 5; WD-repeat protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Others
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • MYC
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human WDR5-2734H Recombinant Human WD Repeat Domain 5, His-tagged E.coli His
Human WDR5-3718H Recombinant Human WDR5, GST-tagged E.coli GST 1-334aa
Human WDR5-244H Recombinant Human WDR5 Protein, His-tagged E.coli His
Human WDR5-31543TH Recombinant Human WDR5, His-tagged E.coli His 334 amino acids
Human WDR5-343HCL Recombinant Human WDR5 293 Cell Lysate HEK293 N/A
Human WDR5-344HCL Recombinant Human WDR5 293 Cell Lysate HEK293 N/A
Human WDR5-6871HF Recombinant Full Length Human WDR5 Protein, GST-tagged In Vitro Cell Free System GST 334 amino acids
Human WDR5-007H Recombinant Human WDR5 Protein E.coli 2-334
Human WDR5-3719H Recombinant Human WDR5 Protein, GST-tagged Wheat Germ GST
Human WDR5-3760H Recombinant Human WDR5 protein, His-SUMO-tagged E.coli His-SUMO 2-334aa
Human WDR5-5590H Recombinant Human WDR5 Protein (Met1-Lys120), N-His tagged E.coli N-His Met1-Lys120
Mouse Wdr5-1016M Recombinant Mouse Wdr5 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat WDR5-6569R Recombinant Rat WDR5 Protein Mammalian Cell His
Rat WDR5-6225R Recombinant Rat WDR5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat WDR5-6225R-B Recombinant Rat WDR5 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish WDR5-12323Z Recombinant Zebrafish WDR5 Mammalian Cell His
Chicken WDR5-1347C Recombinant Chicken WDR5 Mammalian Cell His
CBCRY09 WD-repeat protein 5 E.coli N/A
  • Other Resource

WDR5 involved in several pathways and played different roles in them. We selected most pathways WDR5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

WDR5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by WDR5 itself. We selected most functions WDR5 had, and list some proteins which have the same functions with WDR5. You can find most of the proteins on our site.

Function Related Protein

WDR5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR5 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR5.

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can WDR5 play a role in non-cancerous diseases? 03/25/2023

Yes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.

How does WDR5 affect neurodevelopment? 11/09/2021

WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.

How can WDR5 be used as a diagnostic marker for cancer? 03/02/2019

Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.

Are there any clinical trials involving WDR5-targeted therapies? 02/25/2018

Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.

Is there a connection between WDR5 and autoimmune diseases? 03/29/2017

Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.

Customer Reviews (3)

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Reviews
11/25/2020

    Their ability to accommodate the requirements of large-scale experiments and guarantee a reliable supply streamlines my research operations, eliminating any concerns related to potential shortages.

    10/10/2020

      I am confident that the protein will reliably perform in my assays, providing accurate and reproducible results.

      09/25/2017

        the manufacturer's supply management capabilities assure a seamless and continuous provision of the WDR5 protein.

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