Recombinant Human WDR5 Protein, GST-tagged

Cat.No. : WDR5-3719H
Product Overview : Human WDR5 full-length ORF ( NP_060058.1, 1 a.a. - 334 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ.
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Description : This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 63 kDa
AA Sequence : MATEEKKPETEAARAQPTPSSSATQ SKPTPVKPNYALKFTLAGHTKAVSS VKFSPNGEWLASSSADKLIKIWGAY DGKFEKTISGHKLGISDVAWSSDSN LLVSASDDKTLKIWDVSSGKCLKTL KGHSNYVFCCNFNPQSNLIVSGSFD ESVRIWDVKTGKCLKTLPAHSDPVS AVHFNRDGSLIVSSSYDGLCRIWDT ASGQCLKTLIDDDNPPVSFVKFSPN GKYILAATLDNTLKLWDYSKGKCLK TYTGHKNEKYCIFANFSVTGGKWIV SGSEDNLVYIWNLQTKEIVQKLQGH TDVVISTACHPTENIIASAALENDK TIKLWKSDC
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : WDR5 WD repeat domain 5 [ Homo sapiens (human) ]
Official Symbol : WDR5
Synonyms : WDR5; WD repeat domain 5; SWD3; BIG-3; CFAP89; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; cilia and flagella associated protein 89
Gene ID : 11091
mRNA Refseq : NM_017588
Protein Refseq : NP_060058
MIM : 609012
UniProt ID : P61964

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can WDR5 play a role in non-cancerous diseases? 03/25/2023

Yes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.

How does WDR5 affect neurodevelopment? 11/09/2021

WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.

How can WDR5 be used as a diagnostic marker for cancer? 03/02/2019

Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.

Are there any clinical trials involving WDR5-targeted therapies? 02/25/2018

Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.

Is there a connection between WDR5 and autoimmune diseases? 03/29/2017

Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.

Customer Reviews (3)

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Reviews
11/25/2020

    Their ability to accommodate the requirements of large-scale experiments and guarantee a reliable supply streamlines my research operations, eliminating any concerns related to potential shortages.

    10/10/2020

      I am confident that the protein will reliably perform in my assays, providing accurate and reproducible results.

      09/25/2017

        the manufacturer's supply management capabilities assure a seamless and continuous provision of the WDR5 protein.

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