Recombinant Human WDR5 Protein, GST-tagged

• Cat.No.: WDR5-3719H
• Product Overview: Human WDR5 full-length ORF ( NP_060058.1, 1 a.a. - 334 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 63 kDa
• AA Sequence: MATEEKKPETEAARAQPTPSSSATQ SKPTPVKPNYALKFTLAGHTKAVSS VKFSPNGEWLASSSADKLIKIWGAY DGKFEKTISGHKLGISDVAWSSDSN LLVSASDDKTLKIWDVSSGKCLKTL KGHSNYVFCCNFNPQSNLIVSGSFD ESVRIWDVKTGKCLKTLPAHSDPVS AVHFNRDGSLIVSSSYDGLCRIWDT ASGQCLKTLIDDDNPPVSFVKFSPN GKYILAATLDNTLKLWDYSKGKCLK TYTGHKNEKYCIFANFSVTGGKWIV SGSEDNLVYIWNLQTKEIVQKLQGH TDVVISTACHPTENIIASAALENDK TIKLWKSDC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: WDR5 WD repeat domain 5 [ Homo sapiens (human) ]
• Official Symbol: WDR5
• Synonyms: WDR5; WD repeat domain 5; SWD3; BIG-3; CFAP89; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; cilia and flagella associated protein 89
• Gene ID: 11091
• mRNA Refseq: NM_017588
• Protein Refseq: NP_060058
• MIM: 609012
• UniProt ID: P61964