Recombinant Human WDR5 Protein, GST-tagged
Cat.No. : | WDR5-3719H |
Product Overview : | Human WDR5 full-length ORF ( NP_060058.1, 1 a.a. - 334 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ. |
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Description : | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 63 kDa |
AA Sequence : | MATEEKKPETEAARAQPTPSSSATQ SKPTPVKPNYALKFTLAGHTKAVSS VKFSPNGEWLASSSADKLIKIWGAY DGKFEKTISGHKLGISDVAWSSDSN LLVSASDDKTLKIWDVSSGKCLKTL KGHSNYVFCCNFNPQSNLIVSGSFD ESVRIWDVKTGKCLKTLPAHSDPVS AVHFNRDGSLIVSSSYDGLCRIWDT ASGQCLKTLIDDDNPPVSFVKFSPN GKYILAATLDNTLKLWDYSKGKCLK TYTGHKNEKYCIFANFSVTGGKWIV SGSEDNLVYIWNLQTKEIVQKLQGH TDVVISTACHPTENIIASAALENDK TIKLWKSDC |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | WDR5 WD repeat domain 5 [ Homo sapiens (human) ] |
Official Symbol : | WDR5 |
Synonyms : | WDR5; WD repeat domain 5; SWD3; BIG-3; CFAP89; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; cilia and flagella associated protein 89 |
Gene ID : | 11091 |
mRNA Refseq : | NM_017588 |
Protein Refseq : | NP_060058 |
MIM : | 609012 |
UniProt ID : | P61964 |
Products Types
◆ Recombinant Protein | ||
WDR5-007H | Recombinant Human WDR5 Protein | +Inquiry |
Wdr5-1016M | Recombinant Mouse Wdr5 Protein, MYC/DDK-tagged | +Inquiry |
WDR5-6225R | Recombinant Rat WDR5 Protein, His (Fc)-Avi-tagged | +Inquiry |
WDR5-31543TH | Recombinant Human WDR5, His-tagged | +Inquiry |
WDR5-6569R | Recombinant Rat WDR5 Protein | +Inquiry |
◆ Lysates | ||
WDR5-343HCL | Recombinant Human WDR5 293 Cell Lysate | +Inquiry |
WDR5-344HCL | Recombinant Human WDR5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewTheir ability to accommodate the requirements of large-scale experiments and guarantee a reliable supply streamlines my research operations, eliminating any concerns related to potential shortages.
I am confident that the protein will reliably perform in my assays, providing accurate and reproducible results.
the manufacturer's supply management capabilities assure a seamless and continuous provision of the WDR5 protein.
Q&As (5)
Ask a questionYes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.
WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.
Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.
Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.
Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.
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