Recombinant Human WDR5 293 Cell Lysate
Cat.No. : | WDR5-343HCL |
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Description : | Antigen standard for WD repeat domain 5 (WDR5), transcript variant 2 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Tag : | Non |
Gene Name : | WDR5 WD repeat domain 5 [ Homo sapiens ] |
Official Symbol : | WDR5 |
Synonyms : | WDR5; WD repeat domain 5; WD repeat-containing protein 5; SWD3; Set1c WD40 repeat protein; homolog (S. cerevisiae); WD-repeat protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; BIG-3; |
Gene ID : | 11091 |
mRNA Refseq : | NM_052821 |
Protein Refseq : | ?NP_438172 |
MIM : | 609012 |
UniProt ID : | P61964 |
Chromosome Location : | 9q34 |
Pathway : | Circadian rhythm pathway, organism-specific biosystem; |
Products Types
◆ Recombinant Protein | ||
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Wdr5-1016M | Recombinant Mouse Wdr5 Protein, MYC/DDK-tagged | +Inquiry |
WDR5-6225R | Recombinant Rat WDR5 Protein, His (Fc)-Avi-tagged | +Inquiry |
WDR5-3719H | Recombinant Human WDR5 Protein, GST-tagged | +Inquiry |
WDR5-1347C | Recombinant Chicken WDR5 | +Inquiry |
◆ Lysates | ||
WDR5-344HCL | Recombinant Human WDR5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewTheir ability to accommodate the requirements of large-scale experiments and guarantee a reliable supply streamlines my research operations, eliminating any concerns related to potential shortages.
I am confident that the protein will reliably perform in my assays, providing accurate and reproducible results.
the manufacturer's supply management capabilities assure a seamless and continuous provision of the WDR5 protein.
Q&As (5)
Ask a questionYes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.
WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.
Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.
Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.
Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.
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