Recombinant Human WDR5 protein, His-SUMO-tagged

Cat.No. : WDR5-3760H
Product Overview : Recombinant Human WDR5 protein(P61964)(2-334aa), fused to N-terminal His-SUMO tag, was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : His-SUMO
Form : If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Molecular Mass : 52.5 kDa
Protein length : 2-334aa
AA Sequence : ATEEKKPETEAARAQPTPSSSATQS KPTPVKPNYALKFTLAGHTKAVSSV KFSPNGEWLASSSADKLIKIWGAYD GKFEKTISGHKLGISDVAWSSDSNL LVSASDDKTLKIWDVSSGKCLKTLK GHSNYVFCCNFNPQSNLIVSGSFDE SVRIWDVKTGKCLKTLPAHSDPVSA VHFNRDGSLIVSSSYDGLCRIWDTA SGQCLKTLIDDDNPPVSFVKFSPNG KYILAATLDNTLKLWDYSKGKCLKT YTGHKNEKYCIFANFSVTGGKWIVS GSEDNLVYIWNLQTKEIVQKLQGHT DVVISTACHPTENIIASAALENDKT IKLWKSDC
Purity : Greater than 90% as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.
Gene Name : WDR5 WD repeat domain 5 [ Homo sapiens ]
Official Symbol : WDR5
Synonyms : WDR5; WD repeat domain 5; WD repeat-containing protein 5; SWD3; Set1c WD40 repeat protein; homolog (S. cerevisiae); WD-repeat protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; BIG-3;
Gene ID : 11091
mRNA Refseq : NM_017588
Protein Refseq : NP_060058
MIM : 609012
UniProt ID : P61964

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
11/25/2020

    Their ability to accommodate the requirements of large-scale experiments and guarantee a reliable supply streamlines my research operations, eliminating any concerns related to potential shortages.

    10/10/2020

      I am confident that the protein will reliably perform in my assays, providing accurate and reproducible results.

      09/25/2017

        the manufacturer's supply management capabilities assure a seamless and continuous provision of the WDR5 protein.

        Q&As (5)

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        Can WDR5 play a role in non-cancerous diseases? 03/25/2023

        Yes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.

        How does WDR5 affect neurodevelopment? 11/09/2021

        WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.

        How can WDR5 be used as a diagnostic marker for cancer? 03/02/2019

        Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.

        Are there any clinical trials involving WDR5-targeted therapies? 02/25/2018

        Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.

        Is there a connection between WDR5 and autoimmune diseases? 03/29/2017

        Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.

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