aacs
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  • Official Full Name
  • acetoacetyl-CoA synthetase
  • Background
  • activates acetoacetate to its CoA ester.
  • Synonyms
  • AACS; acetoacetyl-CoA synthetase; ACSF1; acyl CoA synthetase family member 1; FLJ12389; SUR 5; Acetoacetate CoA ligase; ACSF 1; FLJ41251; Homolog of C. elegans supressor of ras 5; Protein sur 5 homolog; SUR5; protein sur-5 homolog; acetoacetate-CoA ligase; acyl-CoA synthetase family member 1; homolog of C. elegans supressor of ras 5 (sur-5); SUR-5
Cat.#:AACS-008HTag:GST
Source (Host):Wheat Germ (in vitro)Species:Human
Product nameRecombinant Human AACS Protein, GST-tagged
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Cat.#:AACS-3338HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human AACS, His tagged
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Cat.#:AACS-1055MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse AACS Protein
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Cat.#:AACS-380RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat AACS Protein
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Cat.#:AACS-257CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus AACS Protein, His-tagged
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Cat.#:AACS-1333CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AACS
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Cat.#:AACS-11242ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish AACS
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Cat.#:AACS-679HCLTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human AACS cell lysate
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Involved Pathway

AACS involved in several pathways and played different roles in them. We selected most pathways AACS participated on our site, such as Valine, leucine and isoleucine degradation, Butanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AACS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Valine, leucine and isoleucine degradation
AOX2P; HIBADH; ACADM; OXCT2; AOX4; HSD17B10; ALDH2.1; ALDH2.2; HIBCH; ALDH3A2
Butanoate metabolism
EHHADH; ACAT1; OXCT2B; ACSM2; HADHAB; ACSM2B; OXCT1; ACAT2; OXCT2; ACSM5

Protein Function

AACS has several biochemical functions, for example, ATP binding, acetoacetate-CoA ligase activity, butyrate-CoA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AACS itself. We selected most functions AACS had, and list some proteins which have the same functions with AACS. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein HSPA1L; MARK1; PRKDC; CSNK1G2B; TOR2A; STRADA; DYRK2; PRKAA2; UBA3; RTCB
Function acetoacetate-CoA ligase activity
Related Protein AACS
Function butyrate-CoA ligase activity
Related Protein Acsm2a; ACSM1; ACSM2; PPP1CA; ACSM2B; ACSM5; ACSM4; ACSM3; AACS
Function protein binding
Related Protein BNIP1; GCET2; UBE4A; EVI5L; TNP1; LCE4A; LY6H; NDUFA13; TMEM106B; S100A13

Interacting Protein

AACS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AACS here. Most of them are supplied by our site. Hope this information will be useful for your research of AACS.
CMTM5