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ACPT

  • Official Full Name

    acid phosphatase, testicular

  • Overview

    Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
  • Synonyms

    ACPT; acid phosphatase, testicular; testicular acid phosphatase; Acid phosphatase testicular;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACPT-186H Recombinant Human ACPT Protein, GST-Tagged Wheat Germ GST
Human ACPT-16HCL Recombinant Human ACPT cell lysate N/A
Human ACPT-241H Recombinant Human ACPT protein, His-tagged E. coli His 146-367 aa
Human ACPT-809HF Recombinant Full Length Human ACPT Protein, GST-tagged In Vitro Cell Free System GST 426 amino acids
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ACPT Related Articles

ACPT involved in several pathways and played different roles in them. We selected most pathways ACPT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACPT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ACPT has several biochemical functions, for example, acid phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACPT itself. We selected most functions ACPT had, and list some proteins which have the same functions with ACPT. You can find most of the proteins on our site.

Function Related Protein
acid phosphatase activityMINPP1B;ACP5;PPIP5K2;ACPL2;ACPT;ACP1;ACP5A;ACPP;PAPL

ACPT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACPT here. Most of them are supplied by our site. Hope this information will be useful for your research of ACPT.

Stachowicz, K; Chojnacka-Wojcik, E; et al. Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent. NEUROPHARMACOLOGY 52:306-312(2007).
  • Q&As
  • Reviews

Q&As (10)

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What is the catalytic mechanism of ACPT? 03/10/2022

The catalytic mechanism of ACPT involves the activation of a serine residue, which acts as a nucleophile to cleave phosphate ester bonds.

What is the role of post-translational modifications in ACPT function? 02/20/2022

Post-translational modifications such as phosphorylation and glycosylation have been shown to regulate the activity of ACPT.

Are there any therapeutic implications of ACPT? 02/19/2022

The ACPT protein has been investigated as a potential therapeutic target for the treatment of prostate cancer, as well as for the development of male contraceptives. However, further research is needed to determine the clinical utility of targeting ACPT.

What is the tissue-specific expression pattern of the ACPT gene? 11/15/2021

The ACPT gene is primarily expressed in the testis, with lower levels of expression observed in the prostate gland.

What is the significance of the ACPT gene in cancer? 07/16/2021

ACPT has been shown to be overexpressed in certain types of cancer, such as prostate cancer and breast cancer, and may play a role in cancer cell growth and survival.

What is the function of the ACPT gene? 09/13/2020

The ACPT gene is primarily expressed in the testis and plays a role in the regulation of spermatogenesis.

What is the protein product of the ACPT gene? 04/12/2020

The protein product of the ACPT gene is the acid phosphatase, testicular isoform, which is an enzyme that hydrolyzes phosphomonoesters at an acidic pH.

What is the promoter region of the ACPT gene? 07/10/2019

The promoter region of the ACPT gene is a sequence of DNA that regulates the transcription of the gene by binding to transcription factors.

Are there any known drugs that target the ACPT gene? 09/11/2018

There are currently no known drugs that target the ACPT gene. However, further research into the function and regulation of the ACPT gene could lead to the development of novel therapeutic interventions in the future.

What are the genetic variations that affect the ACPT gene? 04/12/2018

Genetic variations such as single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) have been identified in the ACPT gene and may contribute to variations in enzyme activity and disease susceptibility.

Customer Reviews (3)

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Reviews
08/15/2022

    A great shopping experience!

    08/07/2022

      Great performance with the lab equipments.

      06/11/2021

        Fast delivery, love it.

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