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Recombinant Human ACPT Protein, GST-Tagged

Cat.No. : ACPT-186H
Product Overview : Human ACPT full-length ORF ( AAI46507.1, 1 a.a. - 426 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 73.81 kDa
AA Sequence : MAGLGFWGHPAGPLLLLLLLVLPPR ALPEGPLVFVALVFRHGDRAPLASY PMDPHKEVASTLWPRGLGQLTTEGV RQQLELGRFLRSRYEAFLSPEYRRE EVYIRSTDFDRTLESAQANLAGLFP EAAPGSPEARWRPIPVHTVPVAEDK LLRFPMRSCPRYHELLREATEAAEY QEALEGWTGFLSRLENFTGLSLVGE PLRRAWKVLDTLMCQQAHGLPLPAW ASPDVLRTLAQISALDIGAHVGPPR AAEKAQLTGGILLNAILANFSRVQR LGLPLKMVMYSAHDSTLLALQGALG LYDGHTPPYAACLGFEFRKHLGNPA KDGGNVTVSLFYRNDSAHLPLPLSL PGCPAPCPLGRFYQLTAPARPPAHG VSCHGPYEAAIPPAPVVPLLAGAVA VLVALSLGLGLLAWRPGCLRALGGP V
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ACPT acid phosphatase, testicular [ Homo sapiens ]
Official Symbol : ACPT
Synonyms : ACPT; acid phosphatase, testicular; testicular acid phosphatase;
Gene ID : 93650
mRNA Refseq : NM_033068
Protein Refseq : NP_149059
MIM : 606362
UniProt ID : Q9BZG2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What is the catalytic mechanism of ACPT? 03/10/2022

The catalytic mechanism of ACPT involves the activation of a serine residue, which acts as a nucleophile to cleave phosphate ester bonds.

What is the role of post-translational modifications in ACPT function? 02/20/2022

Post-translational modifications such as phosphorylation and glycosylation have been shown to regulate the activity of ACPT.

Are there any therapeutic implications of ACPT? 02/19/2022

The ACPT protein has been investigated as a potential therapeutic target for the treatment of prostate cancer, as well as for the development of male contraceptives. However, further research is needed to determine the clinical utility of targeting ACPT.

What is the tissue-specific expression pattern of the ACPT gene? 11/15/2021

The ACPT gene is primarily expressed in the testis, with lower levels of expression observed in the prostate gland.

What is the significance of the ACPT gene in cancer? 07/16/2021

ACPT has been shown to be overexpressed in certain types of cancer, such as prostate cancer and breast cancer, and may play a role in cancer cell growth and survival.

What is the function of the ACPT gene? 09/13/2020

The ACPT gene is primarily expressed in the testis and plays a role in the regulation of spermatogenesis.

What is the protein product of the ACPT gene? 04/12/2020

The protein product of the ACPT gene is the acid phosphatase, testicular isoform, which is an enzyme that hydrolyzes phosphomonoesters at an acidic pH.

What is the promoter region of the ACPT gene? 07/10/2019

The promoter region of the ACPT gene is a sequence of DNA that regulates the transcription of the gene by binding to transcription factors.

Are there any known drugs that target the ACPT gene? 09/11/2018

There are currently no known drugs that target the ACPT gene. However, further research into the function and regulation of the ACPT gene could lead to the development of novel therapeutic interventions in the future.

What are the genetic variations that affect the ACPT gene? 04/12/2018

Genetic variations such as single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) have been identified in the ACPT gene and may contribute to variations in enzyme activity and disease susceptibility.

Customer Reviews (3)

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Reviews
08/15/2022

    A great shopping experience!

    08/07/2022

      Great performance with the lab equipments.

      06/11/2021

        Fast delivery, love it.

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