actb
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  • Official Full Name
  • actin, beta
  • Background
  • This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]
  • Synonyms
  • ACTB; actin, beta; BRWS1; PS1TP5BP1; actin, cytoplasmic 1; beta cytoskeletal actin; PS1TP5-binding protein 1;
Cat.#:ACTB-1025HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ACTB Protein, MYC/DDK-tagged
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Cat.#:ACTB-1520HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human ACTB, GST-tagged
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Cat.#:ACTB-133HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human ACTB
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Cat.#:ACTB-225HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ACTB protein, His-tagged
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Cat.#:ACTB-3030HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Actin, Beta, His-tagged
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Cat.#:Actb-3093MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Actb, His-tagged
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Cat.#:ACTB-478RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ACTB Protein
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Cat.#:ACTB-269CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ACTB Protein, His-tagged
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Cat.#:ACTB-221RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ACTB Protein, His-tagged
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Cat.#:ACTB-7067CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ACTB
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Cat.#:ACTB-325HTag:N/A
Source (Host):Human PlateletsSpecies:Human
Product nameNative Human ACTB
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Cat.#:ACTB-882PTag:
Source (Host):Porcine brainSpecies:Porcine
Product nameNative Porcine ACTB Protein
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Cat.#:ACTB-20HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ACTB cell lysate
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Involved Pathway

ACTB involved in several pathways and played different roles in them. We selected most pathways ACTB participated on our site, such as Rap signaling pathway, Phagosome, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACTB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Rap signaling pathway
RAP1B; INSR; FLT1; GRIN2A; IGF1; SIPA1L2; GNAI3; MLLT4; RALGDS; VEGFC
Phagosome
TUBB2; ATP6V0A2B; ATP6V0A1B; HLA-DRA; TLR2; HLA-DRB4; TUBA8L3; MARCO; ATP6AP1B; ITGB3
Hippo signaling pathway
BMP6; SOX2; MOB1A; SAV1; TEAD2; MPP5; LIMD1; NF2; TGFBR2; ID2
Focal adhesion
ITGB8; MYL10; TLN2A; DIAP1; MYL12.1; RAC3A; PIK3R1; MYL12A; VWF; LAMB1A
Adherens junction
PTPRJ; FYNB; ACTN3B; LMO7; MLLT4; YES1; FER; BAIAP2; BAIAP2A; EP300
Tight junction
PPP2R2CA; PRKCBA; HCLS1; CLDN7B; VMHCL; TJP2; MYLPFA; MYH3; CLDN14; RHOAB
Platelet activation
PIK3R3; MAPK1; MYL12B; TBXAS1; SNAP23; FCER1G; MYLK3; MAPK3; F2RL3; FYN
Leukocyte transendothelial migration
CD99; CLDN2; ACTG1; GNAI1; PIK3CG; NCF4; MLLT4; MYL9; ACTN1; ITGB1
Regulation of actin cytoskeleton
ACTB1; ARHGEF12; ITGA6; MYLK3; ROCK2A; SCIN; FGD3; FGF13B; ITGB1; ITGA2
Thyroid hormone signaling pathway
ATP1A2; MED1; PIK3CB; BAD; KAT2B; MED12L; RCAN1; PLCZ1; NOTCH4; DIO2
Oxytocin signaling pathway
NRAS; CACNA2D2; CALM2; MAPK3; KCNJ14; GNAS; PRKAB2; ITPR1; RYR1; PLA2G4D
Gastric acid secretion
CALML3; PRKACB; ATP1B4; ATP4A; PRKCG; ATP1B1; CAMK2D; CAMK2A; SLC26A7; MYLK
Bacterial invasion of epithelial cells
ARPC3; PXN; CTNNA1; CRK; CTNNA3; CD2AP; RAC1; PIK3R3; CTTN; SHC2
Vibrio cholerae infection
PRKCA; ATP6V1D; ATP6V0A2; PRKACG; ATP6V1G2; TJP1; ATP6V1E2; ATP6V0E1; ATP6V1F; GNAS
Pathogenic Escherichia coli infection
TUBB6; HCLS1; CD14; TUBB1; PRKCA; CDH1; CDC42; WASL; LY96; TUBA1A
Shigellosis
FBXW11; U2AF1L4; IL-8; MAPK13; PFN1; IKBKB; MAPK9; MAPK10; ATG5; WASF1
Salmonella infection
IFNG1-2; FLNC; CXCL3; MAPK11; MAPK8; RAC1; CCL4; KLC4; LBP; NFKB1
Influenza A
PABPN1L; CCL5; IFNGR1; NFKB1; TYK2; HLA-DRB4; TLR3; LOC100033925; IFNGR2; DNAJB1
Proteoglycans in cancer
CAMK2B; MMP2; HPSE; RPS6KB2; WNT9A; PDPK1; CAV3; FZD3; PPP1R12A; ERBB4
Hypertrophic cardiomyopathy (HCM)
TGFB3; ITGA8; SGCB; ITGA1; ITGA2; ITGA2B; ITGA6; ITGAV; TTN; LAMA2
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GJA1; ITGAV; DES; DSG2; ITGA10; ACTN3; ITGA8; SGCA; ITGB3; CDH2
Dilated cardiomyopathy
DMD; SGCD; DAG1; TGFB3; CACNG2; ITGB6; ITGA3; CACNB3; ACTB; CACNG8
Viral myocarditis
EIF4G3; HLA-G; CD80; LAMA2; ACTG1; EIF4G2; HLA-DMA; HLA-DRB4; RAC3; CYCS

Protein Function

ACTB has several biochemical functions, for example, ATP binding, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding, contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACTB itself. We selected most functions ACTB had, and list some proteins which have the same functions with ACTB. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ACSS3; PLK3; IDH3G; DHX15; KIF12; ACTA1B; PI4KB; BMPR1A; ROR2; TTLL5
Function contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein SMARCB1; RBBP4; ACTB; SMARCE1; ACTL6A; SMARCC2; CHD4; MBD3; SMARCC1; HDAC1
Function contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding
Related Protein SMARCA4; SMARCB1; ACTL6A; CHD4; ACTB; SMARCC2; SMARCC1; HDAC1; HDAC2; GATAD2B
Function Tat protein binding
Related Protein DLL1; ACTB; NPM1; GABARAPL1; TRIM32; MDFIC; SMARCA4; SMARCB1
Function identical protein binding
Related Protein RASSF3; KDM6A; ZHX2; AGXT2; NDC80; CAV1; TP63; SERPINA1D; SMAD1; PLIN5
Function kinesin binding
Related Protein MAPK8IP2; KIFAP3; KTN1; SPAG9A; TOR1A; NEFH; ACTB; CD36; PLEKHM2; PIFO
Function nitric-oxide synthase binding
Related Protein CALM1; CAV3; SCN5A; ATP2B4; SNTA1; CALM2; CD74; CDH2; DNM2; CAV1
Function contributes_to nucleosomal DNA binding
Related Protein SMARCC2; HDAC1; SMARCA4; RBBP4; MTA2; SMARCE1; SMARCC1; ACTB; SMARCB1; GATAD2B
Function protein binding
Related Protein APAF1; TRIP10; CBLN3; NSMCE2; NLRC4; HENMT1; BLOC1S2A; C3orf15; CLN5; PKM
Function structural constituent of cytoskeleton
Related Protein NEFH; EPB41L3; ARPC1B; NEFL; KRT17; ACTB; ARPC2; TUBA1A; TUBB6; TUBB1

Interacting Protein

ACTB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACTB here. Most of them are supplied by our site. Hope this information will be useful for your research of ACTB.
ACTG1; CFL1; DSTN; ESR1

ACTB Related Articles

Bonnans, C; Lohela, M; et al. Real-time Imaging of Myeloid Cells Dynamics in Apc(Min/+) Intestinal Tumors by Spinning Disk Confocal Microscopy. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS :-(2014).
Matsumoto, C; Ito, M; et al. Preparation of thyroid follicular cells for mRNA quantification after fluorescence-activated cell sorting. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION 73:245-252(2013).