actb
Share
  • Official Full Name
  • actin, beta
  • Background
  • This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]
  • Synonyms
  • ACTB; actin, beta; BRWS1; PS1TP5BP1; actin, cytoplasmic 1; beta cytoskeletal actin; PS1TP5-binding protein 1;
Cat.#:ACTB-2433CTag:His/Myc
Source (Host):YeastSpecies:Cricetulus Griseus
Product nameRecombinant Cricetulus Griseus ACTB Protein (1-375 aa), His-Myc-tagged
+Inquiry
Cat.#:ACTB-2449CTag:His
Source (Host):E. coliSpecies:Cricetulus Griseus
Product nameRecombinant Cricetulus Griseus ACTB Protein (1-375 aa), His-tagged
+Inquiry
Cat.#:ACTB-1025HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ACTB Protein, MYC/DDK-tagged
+Inquiry
Cat.#:ACTB-1520HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human ACTB, GST-tagged
+Inquiry
Cat.#:ACTB-133HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human ACTB
+Inquiry
Cat.#:ACTB-225HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ACTB protein, His-tagged
+Inquiry
Cat.#:ACTB-3030HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Actin, Beta, His-tagged
+Inquiry
Cat.#:Actb-3093MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Actb, His-tagged
+Inquiry
Cat.#:ACTB-478RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ACTB Protein
+Inquiry
Cat.#:ACTB-269CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ACTB Protein, His-tagged
+Inquiry
Cat.#:ACTB-221RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ACTB Protein, His-tagged
+Inquiry
Cat.#:ACTB-7067CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ACTB
+Inquiry
Cat.#:ACTB-325HTag:N/A
Source (Host):Human PlateletsSpecies:Human
Product nameNative Human ACTB
+Inquiry
Cat.#:ACTB-882PTag:
Source (Host):Porcine brainSpecies:Porcine
Product nameNative Porcine ACTB Protein
+Inquiry
Cat.#:ACTB-20HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ACTB cell lysate
+Inquiry

Involved Pathway

ACTB involved in several pathways and played different roles in them. We selected most pathways ACTB participated on our site, such as Rap signaling pathway, Phagosome, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACTB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Rap signaling pathway
Adcy4; PIK3R5; MAPK11; INS; PLCB4; RALB; SKAP1; PLCE1; GNAI3; CALM2
Phagosome
FAM49BA; M6PR; ATP6V1H; CANX; cgr2b; CD14; H2-Q10; TLR2-1; HLA-DRB5; MHC1UEA
Hippo signaling pathway
CTNNA3; PPP2CA; SNAI2; TGFBR2; PPP2R2C; LLGL1; WNT9B; AJUBA; WNT7A; LLGL2
Focal adhesion
PIK3CD; SEPP1; RAP1B; ITGA2; ZYX; TESK2; CAV3; PIK3CB; ITGB7; ITGAV
Adherens junction
RAC1A; TGFBR1B; RHOA; Fert2; MAPK1; CDH1; MAPK3; WASF1; PVRL1B; FYN
Tight junction
RHOAC; CLDN11B; CLDN15; CLDN3; ACTN2B; MYL9A; EXOC4; MYH9; PARD3; CSNK2A2A
Platelet activation
GNAI2; PPP1CC; SYK; MAPK1; FCER1G; Adcy4; PIK3R5; FCGR2A; FGA; FGB
Leukocyte transendothelial migration
ACTN3; ACTN1; RAP1B; PLCG2; MYL12B; ACTG1; VCL; MSN; CYBA; NCF1
Regulation of actin cytoskeleton
MOS; PAK2A; MAPK6; MAP2K2A; RDX; MYLPFB; MYL2B; PIK3CB; PDGFC; BRAF
Thyroid hormone signaling pathway
NCOA1; MED4; KRAS; ATP1A3; HDAC1; STAT1; MED14; SLCO1C1; PDPK1; HDAC2
Oxytocin signaling pathway
MEF2C; RAF1; CALM3; CAMK2B; MYLK3; PPP3CC; PRKACG; PLCB1; CAMK1D; PPP3R2
Gastric acid secretion
KCNK2; CAMK2B; CAMK2D; SST; PRKCA; GNAQ; CAMK2G; KCNK10; CALM3; ATP1B1
Bacterial invasion of epithelial cells
ITGB1; ACTB; CAV3; BCAR1; ARPC5; SEPT9; MET; HCLS1; CTNNA1; CDH1
Vibrio cholerae infection
KDELR1; ACTG1; ATP6V1E2; ATP6V0D2; ERO1L; PDIA4; ATP6AP1; ATP6V1G1; ATP6V0E1; ATP6V1D
Pathogenic Escherichia coli infection
TUBA3D; HCLS1; ARHGEF2; NCK2; PRKCA; TUBA1C; TUBAL3; YWHAZ; WAS; TUBB
Shigellosis
MAPK8; RIPK2; MAD2L2; RAC1; WASF1; MAPK9; IL-8; UBE2D2; ITGB1; MAPK10
Salmonella infection
PFN2L; MAPK13; ARPC5LA; WASLB; TLR5; MAPK14B; MAPK14A; KLC2; CDC42L; TJP1
Influenza A
TNFRSF10D; IL6; KPNA1; RAF1; HSPA1L; HLA-DRB3; PRSS2; FURIN; KPNA2; HSPA6
Proteoglycans in cancer
ERBB2; WNT1; PPP1CC; MAPK3; CBLB; MMP9; FZD9; SLC9A1; FLNC; WNT4
Hypertrophic cardiomyopathy (HCM)
ITGA3; MYH7; ITGA1; ITGA5; TTN; PRKAG2; SGCD; MYL2; ITGB6; SLC8A1
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ACTB; ITGB1; ACTG1; DES; ITGA7; DAG1; TCF7; EMD; SGCD; CACNG6
Dilated cardiomyopathy
ITGB7; TNNC1; Adcy4; TGFB2; ITGA2; PRKACA; TPM2; ITGA1; CACNG1; CACNG6
Viral myocarditis
CD40; BID; ICAM1; HLA-DRB1; ABL2; CYCS; CD86; EIF4G3; HLA-DMA; HLA-DQA2

Protein Function

ACTB has several biochemical functions, for example, ATP binding, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding, contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACTB itself. We selected most functions ACTB had, and list some proteins which have the same functions with ACTB. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein SRPK1B; STK3; OLA1; CKM; PMELA; DGKQ; UBE2I; MAP3K6; ZNF143B; CAMK1G
Function contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein GATAD2B; SMARCE1; SMARCC2; ACTB; MBD3; SMARCA4; SMARCC1; ACTL6A; HDAC2; SMARCB1
Function contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding
Related Protein GATAD2B; HDAC1; RBBP4; SMARCE1; SMARCA4; SMARCC1; SMARCB1; CHD4; SMARCC2; MTA2
Function Tat protein binding
Related Protein SMARCB1; SMARCA4; DLL1; NPM1; GABARAPL1; ACTB; TRIM32; MDFIC
Function identical protein binding
Related Protein VIM; CASC3; RBM10; ROBO1; TRIP13; DAPK1; SDF4; ATG101; TOPBP1; SELK
Function kinesin binding
Related Protein MAPK8IP2; ARPC2; PIFO; IFT88; PPIAL4A; SPAG9; KIFAP3; DISC1; KIAA1279; SERPINB1A
Function nitric-oxide synthase binding
Related Protein CAMK2D; CALM3; DNM3; SNTA1; CD74; DNM2; DMD; SCN5A; CAV1; CAV3
Function contributes_to nucleosomal DNA binding
Related Protein MTA2; SMARCB1; HDAC2; GATAD2B; ACTL6A; SMARCC1; HDAC1; CHD4; ACTB; SMARCC2
Function protein binding
Related Protein STOML1; LUC7L; SNX1; RBL2; MIS12; MST1R; CTPS2; RPSA; TGFBR2; STAMBP
Function structural constituent of cytoskeleton
Related Protein TUBB4A; TNNT2A; ARPC5; TUBB2B; KRT17; KRT15; ARPC2; TLN2A; BFSP2; MAPT

Interacting Protein

ACTB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACTB here. Most of them are supplied by our site. Hope this information will be useful for your research of ACTB.
ACTG1; CFL1; DSTN; ESR1

ACTB Related Articles

Bonnans, C; Lohela, M; et al. Real-time Imaging of Myeloid Cells Dynamics in Apc(Min/+) Intestinal Tumors by Spinning Disk Confocal Microscopy. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS :-(2014).
Matsumoto, C; Ito, M; et al. Preparation of thyroid follicular cells for mRNA quantification after fluorescence-activated cell sorting. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION 73:245-252(2013).