Recombinant Human ACTB Protein Pre-coupled Magnetic Beads

Cat.No. : ACTB-267H-B
Product Overview : The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.
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Source : HEK293
Species : Human
Form : Solution
Particle size : ~2 μm
Beads Surface : Hydrophilic
Capacity : > 200 pmol rabbit IgG/ mg beads
Applications : Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
Stability : Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
Storage : 2-8℃. Do not to freeze thaw the Beads
Concentration : 10mg beads/mL
Storage Buffer : PBS buffer
Gene Name : ACTB actin beta [ Homo sapiens (human) ]
Official Symbol : ACTB
Synonyms : BRWS1; PS1TP5BP1
Gene ID : 60
mRNA Refseq : NM_001101.5
Protein Refseq : NP_001092.1
MIM : 102630
UniProt ID : P60709

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (5)

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Reviews
08/19/2022

    I could trust the product's precision, ensuring reliable data generation

    08/15/2021

      The protein product had an impressive shelf life, maintaining its quality and functionality over an extended period

      03/04/2021

        The protein product seamlessly integrated with various experimental techniques, enhancing its versatility

        02/23/2020

          The protein product underwent rigorous safety testing, ensuring its reliability and suitability for experimentation

          06/19/2018

            The protein product line offered a wide variety of options for different research need

            Q&As (20)

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            Which biological process GO terms were identified through the PPI analysis? 12/12/2022

             The PPI analysis identified several biological process GO terms such as "Actin cytoskeleton organization," "Box C/D snoRNP assembly," "Actin filament depolymerization," "Cell junction assembly," and "DNA repair."

             What was the focus of the current study mentioned? 01/25/2022

            The current study aimed to analyze the diagnostic value of ACTB and predict its independent prognostic factor in distinct cancer subtypes using detailed in silico analysis.

            How could ACTB potentially serve as a biomarker in LIHC, HNSC, and LUAD? 11/23/2021

            The findings suggest that due to its elevated expression, association with poorer survival and metastasis, and correlation with important parameters such as immune infiltration and tumor purity, ACTB has the potential to be a candidate biomarker for LIHC, HNSC, and LUAD.

            How is ACTB related to the metastasis of different cancers? 07/30/2021

            The dysregulation and polymerization of ACTB have been revealed to be associated with the metastasis of different cancer types.

            Which drugs were found to reduce the expression level of ACTB? 05/19/2021

            Warfarin and aflatoxin B1 were found to potentially reduce the expression level of ACTB.

            How many highly significant transcription factors (TFs) were identified as potential regulators of ACTB expression? 04/01/2021

            Ten highly significant TFs were identified as potential regulators of ACTB expression. They are AATF, WWTR1, GFI1, NR3C1, MYC, GFI1, STAT3, ING1, MAX, and POU4F1.

            What do the results suggest about the regulation of ACTB expression? 11/25/2020

            The results indicate that a variety of different regulators, including miRNAs and TFs, are involved in the regulation of ACTB expression.

            What analytical method was used to identify potential regulators of ACTB expression? 12/18/2019

            Enrichr analysis was used to identify potential regulators of ACTB expression.

            What molecular functions were associated with the ACTB-associated genes? 07/08/2019

            The molecular functions associated with the ACTB-associated genes included "Actin monomer binding," "ATPase activity," "Leucine zipper domain binding," and "DNA helicase activity."

            Which drugs were found to elevate the expression level of ACTB? 06/07/2019

            Valporic acid and metribolone were found to potentially elevate the expression level of ACTB.

            What is the significance of ACTB (eta-actin) as a housekeeping gene? 01/01/2019

            ACTB serves as a housekeeping gene commonly used as a control in measuring gene expression in various diseases.

            How many miRNAs were found to have the potential to change ACTB expression? 09/24/2018

            Ten miRNAs were identified as potential regulators of ACTB expression. They are hsa-miR-1908, hsa-miR-663, hsa-miR-744, hsa-miR-4745-3p, hsa-miR-1538, hsa-miR-3960, hsa-miR-4749-5p, hsa-miR-4706, hsa-miR-4743, and hsa-miR-3180-3p.

            In which specific cancers was elevated ACTB expression associated with poorer survival and metastasis? 06/10/2018

            Elevated ACTB expression was associated with poorer survival and metastasis specifically in liver hepatocellular carcinoma (LIHC), head and neck squamous cancer (HNSC), and lung adenocarcinoma (LUAD).

            What did the protein-protein interaction (PPI) analysis reveal about ACTB-associated genes? 07/06/2017

            The PPI analysis revealed a set of ten ACTB-associated genes that are involved in various biological processes, including "Actin cytoskeleton organization," "Box C/D snoRNP assembly," "Actin filament depolymerization," "Cell junction assembly," and "DNA repair."

            What analytical approach was used in the study? 06/21/2017

            The study utilized in silico analysis to assess the diagnostic value and independent prognostic factor of ACTB in different cancer subtypes.

            How was ACTB expression influenced through CTD analysis? 06/17/2017

            Through CTD analysis, it was observed that ACTB expression can potentially be influenced by a number of drugs.

            Which cancers have been found to have a close association with ACTB expression? 05/22/2017

             ACTB expression has been found to be closely related to various cancers, including liver, pancreatic, renal, colorectal, melanoma, prostate, esophageal, lung, gastric, breast, and ovarian cancers.

            How was ACTB-associated expression regulated in the study? 10/26/2016

            The study explored ACTB-associated clinically important expression regulators, including TFs (transcription factors), miRNAs, and different chemotherapeutic drugs.

            What was observed regarding ACTB expression in major human cancer tissues compared to normal samples? 05/21/2016

            ACTB expression was found to be remarkably higher in 24 major human cancer tissues compared to normal samples.

            What other parameters did ACTB up-regulation show interesting correlations with? 01/23/2016

            ACTB up-regulation showed interesting correlations with immune infiltration of CD4+ T and CD8+ T cells, tumor purity, mutant genes, and other important parameters.

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