| Official Full Name | ADAM metallopeptidase domain 23 |
| Background | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. |
| Synonyms | ADAM23; ADAM metallopeptidase domain 23; a disintegrin and metalloproteinase domain 23; disintegrin and metalloproteinase domain-containing protein 23; MDC3; MDC-3; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
ADAM23 involved in several pathways and played different roles in them. We selected most pathways ADAM23 participated on our site, such as Developmental Biology, LGI-ADAM interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | KCNQ2; EPHA2; PAQR3B; SMAD3B; KBTBD7; NTN1B; EPHA4A; COL6A3; MED21; MYOG |
| LGI-ADAM interactions | ADAM22; CACNG8A; LGI2A; STX1B; LGI1A; LGI4; LGI1B; LGI3; LGI2; LGI1 |
ADAM23 has several biochemical functions, for example, integrin binding, metalloendopeptidase activity, metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM23 itself. We selected most functions ADAM23 had, and list some proteins which have the same functions with ADAM23. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| integrin binding | LAMB2; CYR61L1; S1PR2; CALR; ACTN2; ESM1; NISCH; ITGA3; TSPAN4; ADAM23 |
| metalloendopeptidase activity | UQCRC2B; ADAMTS15; MEP1A.2; BMP1; ADAM32; BMP1A; ECE2; PHEX; MMP2; UQCRC2A |
| metallopeptidase activity | TMEM27; NPEPPS; ACY1; MMP25; PAPPA2; DPEP3; ADAM20; ADAM15; C6AST3; CPD |
| protein binding | MED16; RBM8A; ZFPM2; SATB1; TTC17; DOHH; HIC1; HYPM; TRPC7; HSPB1 |
| zinc ion binding | MLL1; ZFP326; TAF3; TTF2; ZCRB1; PPARAB; ERAP2; DTX2; S100B; RYBPA |
ADAM23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM23 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM23.
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